Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Just got my test results back, not sure how to interpret


morsey

Recommended Posts

morsey Newbie
(edited)

Hello all first time poster here.

Since it's early where I am, I have to wait a bit until I get an e-mail from my doctor, so I will ask you all in the meantime your opinions. I took the tTG-IgA test yesterday and got my results just this morning on my iPhone:

"

TTG IGA ANTIBODY 4.7   <20  
TTG IGA INTERPRETATION Negative   Negative

A negative result indicates no tTG IgA antibody or the 
antibody concentration is below the negative cut-off
of the assay."

So I know it's saying negative, but the comment is throwing me off for some reason. Worth to point out that on the mayo clinic's website they have 4.0-10.0 range as "weak positive."

Additionally, they also took an IgA test (not sure the purpose of this test), and my IgA Serum is higher than the normal range. The normal range, according to my hospitals website, is 82 - 453 mg/dL, mine is 516 mg/dL and is flagged as high in my test report.

I do also have to point out, every work day I would spend most of the day "gluten-free" (paleo) but would eat gluten after work when I get home. I did this because I would develop unpleasant symptoms whenever I ate a gluten product, like a sandwich at lunch, and would try to avoid that as much as possible since I was at work. I don't know if this may have had contributed to possibly giving a false negative. At any rate, look forward to your thoughts.

Edited by morsey

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



kareng Grand Master
1 hour ago, morsey said:

Hello all first time poster here.

Since it's early where I am, I have to wait a bit until I get an e-mail from my doctor, so I will ask you all in the meantime your opinions. I took the tTG-IgA test yesterday and got my results just this morning on my iPhone:

"

TTG IGA ANTIBODY 4.7   <20  
TTG IGA INTERPRETATION Negative   Negative

A negative result indicates no tTG IgA antibody or the 
antibody concentration is below the negative cut-off
of the assay."

So I know it's saying negative, but the comment is throwing me off for some reason. Worth to point out that on the mayo clinic's website they have 4.0-10.0 range as "weak positive."

Additionally, they also took an IgA test (not sure the purpose of this test), and my IgA Serum is higher than the normal range. The normal range, according to my hospitals website, is 82 - 453 mg/dL, mine is 516 mg/dL and is flagged as high in my test report.

I do also have to point out, every work day I would spend most of the day "gluten-free" (paleo) but would eat gluten after work when I get home. I did this because I would develop unpleasant symptoms whenever I ate a gluten product, like a sandwich at lunch, and would try to avoid that as much as possible since I was at work. I don't know if this may have had contributed to possibly giving a false negative. At any rate, look forward to your thoughts.

Sometimes, the different labs have a slightly different test or testing equipment.  So the ranges for this type of test can be slightly different. 

The total IGA test is done to validate the ttg IGA test.  A simple explanation is that it tests to see if you are able to make enough IGAs to do a ttg IGA test.  A few people do not make them , so they would need a different test.  

cyclinglady Grand Master

Hi!  Some celiacs, like ME, never get a positive on the TTG IgA, even when given repeatedly.  I only test positive to the DGP IgA.  I am biopsy-confirmed and have healed based on repeat biopsies.  I also have an elevated IgA which is attributed to autoimmune disease or other rare things that I personally do not worry about.  

You could have been gluten light.  You might see if you can get the entire celiac panel.  Do you have other autoimmune disorders or biomarkers like anemia that caused you to to suspect celiac disease?  I ask because I think my doctor ordered a complete panel because I had anemia and was already diagnosed with autoimmune thyroiditis and I did not suffer from GI issues at the time.   Thank goodness he did!  

RMJ Mentor

Each manufacturer of the TTG IgA test sets their own units and their own range - so your result was negative.  However, some people who have celiac disease are negative on the TTG but positive on the DGP (deamidated gliadin peptide) antibody test.  Since you get symptoms you might ask your doctor for that one too.

morsey Newbie
(edited)
9 minutes ago, cyclinglady said:

Hi!  Some celiacs, like ME, never get a positive on the TTG IgA, even when given repeatedly.  I only test positive to the DGP IgA.  I am biopsy-confirmed and have healed based on repeat biopsies.  I also have an elevated IgA which is attributed to autoimmune disease or other rare things that I personally do not worry about.  

You could have been gluten light.  You might see if you can get the entire celiac panel.  Do you have other autoimmune disorders or biomarkers like anemia that caused you to to suspect celiac disease?  I ask because I think my doctor ordered a complete panel because I had anemia and was already diagnosed with autoimmune thyroiditis and I did not suffer from GI issues at the time.   Thank goodness he did!  

I do have anemia, but that it due to my thalessmia. It is interesting to know whether or not my genetic thalessimia could be concealing thalessimia due to celiac? And what do you mean by gluten light? As in I didn't eat enough gluten before the test? I think I ate a pretty reasonable amount, especially on the weekends. As far as I know, I don't have any autoimmune issues that I am aware of. My primary symptoms have been digestion related, with joint pain (knees), and brain fog as secondary.

Edited by morsey
morsey Newbie
3 minutes ago, RMJ said:

Each manufacturer of the TTG IgA test sets their own units and their own range - so your result was negative.  However, some people who have celiac disease are negative on the TTG but positive on the DGP (deamidated gliadin peptide) antibody test.  Since you get symptoms you might ask your doctor for that one too.

That's a good point, I wasn't aware of that. I don't know why, I get shy to keep making requests - like I'm a bother or they may feel like I'm transgressing my limits by telling them what tests to run when they didn't recommend it. But I will ask the doc. I want to make sure I am covered from all sides.

cyclinglady Grand Master
16 minutes ago, morsey said:

I do have anemia, but that it due to my thalessmia. It is interesting to know whether or not my genetic thalessimia could be concealing thalessimia due to celiac? And what do you mean by gluten light? As in I didn't eat enough gluten before the test? I think I ate a pretty reasonable amount, especially on the weekends. As far as I know, I don't have any autoimmune issues that I am aware of. My primary symptoms have been digestion related, with joint pain (knees), and brain fog as secondary.

Wow!  I also have Thalassemia which masked my iron-deficiency anemia (“oh, your hemoglobin is low because of your Thalassemia” or “your periods must be heavy”.  So, you can have more than one type of anemia.  Your doctor should check your iron levels (how you process iron) and iron stores (ferritin).  B-12 should be checked because despite your having tiny blood cells (B-12 deficiency usually cause large blood cells), you can be low in B-12.   Celiac disease usually damages the intestinal villi making it difficult to absorb nutrients like iron and vitamins. 

You only need to be consuming 1 to 2 slices of bread per day or equivalent.  

Your symptoms could be celiac disease or something else like Crohn’s.  Be sure to get throughly evaluated.  Be persistent.  Something is wrong!  


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



morsey Newbie
3 hours ago, cyclinglady said:

Wow!  I also have Thalassemia which masked my iron-deficiency anemia (“oh, your hemoglobin is low because of your Thalassemia” or “your periods must be heavy”.  So, you can have more than one type of anemia.  Your doctor should check your iron levels (how you process iron) and iron stores (ferritin).  B-12 should be checked because despite your having tiny blood cells (B-12 deficiency usually cause large blood cells), you can be low in B-12.   Celiac disease usually damages the intestinal villi making it difficult to absorb nutrients like iron and vitamins. 

You only need to be consuming 1 to 2 slices of bread per day or equivalent.  

Your symptoms could be celiac disease or something else like Crohn’s.  Be sure to get throughly evaluated.  Be persistent.  Something is wrong!  

Thank you! I will look into it!

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      131,847
    • Most Online (within 30 mins)
      7,748

    rossick11
    Newest Member
    rossick11
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Colleen H
      Do you or anyone know alot about ibuprofen  I wasn't sure if I was eating too much apple sauce.   Something is making my pain so much worse  I'm referring to the intense pins and needles in my feet and lower legs.  Jaw actually has tardive dystonia and muscle spasms throughout my back Almost like an opposite effect that a pain reliever would do. I'm fairly new to this. Whatever is going on seems to be worsening  Do people get a withdrawal effect from gluten?  It's extremely painful 😖  I'll post that question or research on the site  Thank you everyone for responding 
    • Colleen H
    • Colleen H
      I think I found a huge culprit for severe reactions to create worsening of my c symptoms. Do people with celiac have sensitivity and /or have opposite reaction to certain medications Where can I find a list ?  I'm new here I'm.wondering why I am getting worse when I take certain medicine...the burning feet.  Rebound muscle pain so intense  How many people get opposite effects or have a horrible attack after these meds
    • Colleen H
      Does anyone know if that includes scrambled eggs and healthy smart butter (,gluten free) I add a very tiny amount of margarine less than a teaspoon.  I did no't have any bread    It just seems like no matter what I eat my stomach and nerves over fire and here comes a host of horrible symptoms. My lower abdomen feels horrible, my right leg thigh muscle.. very odd. Jaw pain. Burning feet , joint pain , you name it  The anxiety just creeps up into brain fog. I don't think I could explain this to anyone who is unfamiliar.  Also,  I most likely will not remember posting this until I check it.  This is highly unusual for me because I have an excellent memory.  One weekend before I knew anything about celiac I lost an entire weekend from severe brain fog, confusion, pain, etc.  I honestly thought I was losing my mind. When I think back I recall eating a lot of PBJ sandwiches and turkey sandwiches.  Once again did not know about gluten.  I was just too sick to cook. Do people fast during attacks ?? It seems horrible to keep going through this. I hope I'm not causing my own problems... I wonder if I should fast because I'm not eating gluten .  Chicken ,  scrambled eggs no milk , canned carrots,  gluten free low sugar low fat Greek yogurt which I already posted about 😞 Any suggestions I am open... I am bedridden when this happens to me.  Thank you Celiac community. 🙏🏻❤️      
    • Juliane
      Yeah, that sounds super familiar. When inflammation levels are high — especially at the start of changing your diet — the body often develops a fructose and lactose intolerance. Unfortunately, the only thing that really helps is cutting out anything that isn’t lactose-free or that contains sugar. So basically, stick to meat, veggies, fish…
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.