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Biopsy


lemonade

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lemonade Enthusiast

If someone has been on a Gluten free diet for say 1-2 weeks and they have a biopsy, clould this dramatically change their results?

L


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trents Grand Master
If someone has been on a Gluten free diet for say 1-2 weeks and they have a biopsy, clould this dramatically change their results?

L

The docs don't want you to start the gluten free diet before the biopsy but if you have been a Celiac for sometime there probably is enough damage done to the villi that it would take more than a couple of weeks to repair. They say it takes 6 months to 2 years for healing to be complete. Better inform your doctor, however, that you have already been on the gluten free diet.

DavidB Apprentice

I was just diagnosed, however I still haven't gotten the official results of the biopsy.

I was feeling bad for about a year and my sister told me she had Celiac Spu. I had no idea what it was and said "so.... I got a fake tree for christmas" :D

My blood work came back positive and my family doctor told me to start the diet right away. After two weeks I felt better than I ever did in the last year. Then my GI specialist called and said do not stay on the diet until after the biopsy because it could come up negative.

I hope we can learn together. This site is great!!

Rachel--24 Collaborator
I was feeling bad for about a year and my sister told me she had Celiac Spu. I had no idea what it was and said "so.... I got a fake tree for christmas" :D

LOL....thats funny. :lol:

Glad you got diagnosed. Welcome to the board! :)

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    • trents
      Let me hasten to add that if you will be undergoing an endoscopy/biopsy, it is critical that you do not begin efforts to reduce gluten beforehand. Doing so will render the results invalid as it will allow the small bowel lining to heal and, therefore, obscure the damage done by celiac disease which is what the biopsy is looking for.
    • Scott Adams
      This article, and the comments below it, may be helpful:    
    • Scott Adams
      That’s a really tough situation. A few key points: as mentioned, a gluten challenge does require daily gluten for several weeks to make blood tests meaningful, but negative tests after limited exposure aren’t reliable. Dermatitis herpetiformis can also be tricky to diagnose unless the biopsy is taken from normal-looking skin next to a lesion. Some people with celiac or DH don’t react every time they’re exposed, so lack of symptoms doesn’t rule it out. Given your history and family cancer risk, this is something I’d strongly discuss with a celiac-experienced gastroenterologist or dermatologist before attempting a challenge on your own, so risks and benefits are clearly weighed.
    • Greymo
      https://celiac.org/glutenexposuremarkers/    yes, two hours after accidents ingesting gluten I am vomiting and then diarrhea- then exhaustion and a headache. see the article above- There is research that shows our reactions.
    • trents
      Concerning the EMA positive result, the EMA was the original blood test developed to detect celiac disease and has largely been replaced by the tTG-IGA which has a similar reliability confidence but is much less expensive to run. Yes, a positive EMA is very strong evidence of celiac disease but not foolproof. In the UK, a tTG-IGA score that is 10x normal or greater will often result in foregoing the endoscopy/biopsy. Weaker positives on the tTG-IGA still trigger the endoscopy/biopsy. That protocol is being considered in the US but is not yet in place.
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