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Alba Therapeutics

happygirl

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happygirl Collaborator
happygirl
Posted

Although I live in Virginia Beach, I went to the Richmond GIG group meeting last night to hear Dr. Blake Paterson, the CEO and co-founder of Alba Therapeutics, speak about their new drug and the role of zonulin.

We have all heard about the drug study that is going on for "AT-1001" and that it has been deemed a "Fast Track" drug by the FDA because there is currently no treatment or cure for Celiac.

Dr. Paterson said that on Monday, a press release will be issued, stating the SUCCESS of Phase 1 Testing!!!!!!!!!

Needless to say, everyone in the room was thrilled. He said there were minimal side effects, and that their hypothesis was fully supported. (i.e., that zonulin is over expressed in Celiacs.....this overexpression leads to the "opening" of the gates 'tight junctions' between cells....and this is what allows gluten to permeate the gut).

He said based on their research, a drug for Celiacs to take before a meal (if they think there will be gluten in it) will be available in 2-5 years. There is also much hope for this drug to treat other autoimmune disorders like Type 1 diabetes, MS, RA, etc. They have done research on Type 1 diabetes and have discovered the importance of leaky gut/zonulin/tight junctions in this as well.

The presentation last night was fascinating to me. He really shed light on how the autoimmune reaction occurs, and the role of zonulin and tight junctions.

I asked if it was ok to post on this board about his presentation and he said it was ok with him. I just had to share this with everyone :D

Way to go, Dr. Fassano and Dr. Paterson!!!!!!!!!!!!!

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Canadian Karen Community Regular
Canadian Karen
Posted

Wow! That sounds like really promising news!!!!!

Thanks!

Karen

jerseyangel Proficient
jerseyangel
Posted

Laura--Thanks for letting us know! That was very interesting :)

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