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Poll: How Many Had Elevated Liver Enzymes?


trents

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trents Grand Master

How many of you had elevated liver enzymes as one of your presenting medical issues before Celiac diagnosis?


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Jenn2005 Contributor

My husband has elevated liver enzymes. His weren't elevated before dx or even right after but they were at this last visit. He was dx last August. His doctor tested him for Hepatitis and he had Ultra Sounds and CT Scans to check for other things going on and since everything else was negative he said its from the Celiac and he'll monitor the levels and they should go down once he's healed more.

Jennifer

Guest Robbin

Count me in on that crazy symptom, too. Have had this off and on for ten years and was tested for hepatitis, and was told it was fatty liver disease common in diabetes, but I don't HAVE diabetes, so the drs. are stumped (of course) :)

angielackner Contributor

my liver enzymes are slightly high...i had them tested when i was being tested for PCOS (which I have)...they had to test me before i could do any kind of fertility treatment...and we have not been able to figure out why they were slightly elevated...celiac had never occured to me...i dont have an "official" diagnosis of celiac...but i do most likely have it...or at least for sure a gluten intolerance...i'll have to bring this up with my GI doc when i see him next.

angie

Bonnie Explorer

I kept waking up in the morning with a yellow face and eyes. Also incredibly nauseous. Had bloods tests which revealed I have very high billirubin (liver enzymes). Doctor says that I have Gilbert's Syndrome. Have I? Who knows - these quacks talk a lot of rubbish.

Yvonne

zakismom Newbie

Before diagnosis my liver enzymes were all over the place, some were too high others were too low. My GP sent me to a liver specialist gastroenterologist- who of course checked for everything else first.

ravenwoodglass Mentor
How many of you had elevated liver enzymes as one of your presenting medical issues before Celiac diagnosis?

Mine were slightly elevated at times. My twin however had his liver deteriorating since birth. We have no way to know if this was celiac related as he passed away at 15, at that time his liver had been totally destroyed. Please be aware that you should not drink or take tylenol if your enzymes are elevated. Especially if you are young and still growing liver damage can be greatly accelerated.


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pturse Apprentice

My liver enzymes were elevated too. It was not the case my entire life though, only during a certain period. Went on the diet when first diagnosed (after the whole Hepatitis testing blah blah). Liver was okay after that. Went OFF the diet for a period of 6-8 months and felt absolutely fine but I ran a marathon and I guess that was too much for my body to take and my liver started acting up again and I lost some weight and the color in my face. Started back on the diet in Feb. 06 and have gained a bunch of weight back (ugh), have the color back in my face and I think my enzymes are fine. We shall see, I am donating platelets this weekend and I can ususally tell how my levels are doing by my iron tests during the donation period. I know that isn't a "scientific" way of judging but is a good indication for me.

jenvan Collaborator

pturse-

Why did you end up going off the diet?

plantime Contributor

My liver enzymes were in the very low end of the normal range last time they were tested. Doc said it was perfectly normal, but I started taking herbs to treat sluggish liver, and I feel much better!

  • 2 weeks later...
Guest snowy
How many of you had elevated liver enzymes as one of your presenting medical issues before Celiac diagnosis?

I was diagnosed with Gilbert's syndrome about 10 years ago. My bilirubin was 3x higher than normal.

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      Currently, there are no tests for NCGS. Celiac disease must first be ruled out and we do have testing for celiac disease. There are two primary test modalities for diagnosing celiac disease. One involves checking for antibodies in the blood. For the person with celiac disease, when gluten is ingested, it produces an autoimmune response in the lining of the small bowel which generates specific kinds of antibodies. Some people are IGA deficient and such that the IGA antibody tests done for celiac disease will have skewed results and cannot be trusted. In that case, there are IGG tests that can be ordered though, they aren't quite as specific for celiac disease as the IGA tests. But the possibility of IGA deficiency is why a "total IGA" test should always be ordered along with the TTG-IGA. The other modality is an endoscopy (scoping of the upper GI track) with a biopsy of the small bowel lining. The aforementioned autoimmune response produces inflammation in the small bowel lining which, over time, damages the structure of the lining. The biopsy is sent to a lab and microscopically analyzed for signs of this damage. If the damage is severe enough, it can often be spotted during the scoping itself. The endoscopy/biopsy is used as confirmation when the antibody results are positive, since there is a small chance that elevated antibody test scores can be caused by things other than celiac disease, particularly when the antibody test numbers are not particularly high. If the antibody test numbers are 10x normal or higher, physicians will sometimes declare an official diagnosis of celiac disease without an endoscopy/biopsy, particularly in the U.K. Some practitioners use stool tests to detect celiac disease but this modality is not widely recognized in the medical community as valid. Both celiac testing modalities outlined above require that you have been consuming generous amounts of gluten for weeks/months ahead of time. Many people make the mistake of experimenting with the gluten free diet or even reducing their gluten intake prior to testing. By doing so, they invalidate the testing because antibodies stop being produced, disappear from the blood and the lining of the small bowel begins to heal. So, then they are stuck in no man's land, wondering if they have celiac disease or NCGS. To resume gluten consumption, i.e., to undertake a "gluten challenge" is out of the question because their reaction to gluten is so strong that it would endanger their health. The lining of the small bowel is the place where all of the nutrition in the food we consume is absorbed. This lining is made up of billions of microscopically tiny fingerlike projections that create a tremendous nutrient absorption surface area. The inflammation caused by celiac disease wears down these fingers and greatly reduces the surface area needed for nutrient absorption. Thus, people with celiac disease often develop iron deficiency anemia and a host of other vitamin and mineral deficiencies. It is likely that many more people who have issues with gluten suffer from NCGS than from celiac disease. We actually know much more about the mechanism of celiac disease than we do about NCGS but some experts believe NCGS can transition into celiac disease.
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      Thank you for the clarification and for taking the time to explain the terminology so clearly. I really appreciate your insight, especially the distinction between celiac disease and NCGS and how anemia can point more toward celiac. This was very helpful for me.
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