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Help with test result


Wendy1994

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Wendy1994 Rookie

I am hoping for some assistance in interpreting these results.  Have had symptoms for years.  I used to experience lots of bloating and abdominal pain, thought it was dairy.  In the last year or more I have experienced pain in joints, feet pain, low vitamin D, teeth cracking, burning sensations throughout body, sleep issues, and diarrhea.  Was negative for RA, Lupus, Lyme, B12 and B6 deficiency, MS, and lots of other tests. Started on the road of testing for Celiac.  My biopsy was negative for celiac.  However, my doctor recommended I go gluten free.  I was just reviewing some of my past test results and see I was slightly elevated on one of the tests while I was eating gluten (see attached).  I don’t see my doctor until middle of May and wondering if anyone can help me interpret.  I had seen this was slightly high previously but really didn’t understand much and so much info was given to me that my head was exploding. Any help is greatly appreciated.  Thanks!
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RMJ Mentor

Immunoglobulin A just looks at your total IgA antibody.  It is run because if low, the IgA test for celiac disease may not be valid.

Your total IgA is a little bit high but probably close enough to the normal range to not worry about it being high.

The celiac test is the Tissue Transglutaminase IgA and it is negative for celiac disease.

Hope this helps.

Wendy1994 Rookie

Thank you so much!  Your explanation makes a lot of sense.  I do have a follow up question, what testing is done for gluten sensitivity?  Is there a specific name for the test (who knows, I may have had it since I have had so many tests).  Thanks!

RMJ Mentor

There is no test generally recognized by scientists for non-celiac gluten sensitivity.

Scott Adams Grand Master

Yes, unfortunately this test result does not exclude NCGS, which around 10% of people have, while only ~1% have celiac disease. If you have unexplained symptoms that seem to be associated with gluten consumption, you may still want to go gluten-free for a while to see if you get relief.

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      Hi @Atl222 As @trents points out, there could be many reasons for this biopsy result.  I am interested to know, is your gastroenterologist concerned?  Also, are your blood tests showing steady improvement over the years? I remember when I had my last biopsy, several years after diagnosis, mine came back with with raised lymphocytes but no villous damage, too! In my own case, my consultant wasn't remotely concerned - in fact, he said I might still get this result even if all I ever did was eat nothing but rice and water.   My coeliac blood tests were still steadily improving, albeit slowly, which was reassuring.
    • trents
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      This is a solid, well-reasoned approach. You’re right that “koji” by itself doesn’t indicate gluten status, and the risk really does come down to which grain is used to culture it. The fact that you directly contacted Eden Foods and received a clear statement that their koji is made from rice only, with no wheat or barley, is meaningful due diligence—especially since Eden has a long-standing reputation for transparency. While the lack of gluten labeling can understandably give pause, manufacturer confirmation like this is often what people rely on for traditionally fermented products. As always, trusting your body after trying it is reasonable, but based on the information you gathered, your conclusion makes sense.
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