Ttg iga 67.7 range 0<20

[Dawn s D]

Hi.i have just had my biopsy results through.says all normal.during colonoscopy they said bilary gastritis and what looks like h pylori due to inflammation present?the biopsy says no histological evidence of inflammation infection or celiac?what happens next?he said the findings are contradicts the bloods.he is advising his colleague and handing me back to  gp?what next?

[Dawn s D]

22 minutes ago, Dawn s D said:

Hi.i have just had my biopsy results through.says all normal.during colonoscopy they said bilary gastritis and what looks like h pylori due to inflammation present?the biopsy says no histological evidence of inflammation infection or celiac?what happens next?he said the findings are contradicts the bloods.he is advising his colleague and handing me back to  gp?what next?

He discharging me from colorectal Consultant and handing me back to gastrologist.i didn't make that quite clear in above post

[Scott Adams]

Since you have a positive blood test for celiac disease (I believe), you could still have it, or non-celiac gluten sensitivity, which around 10% of people have but there are not tests yet for it. I would try out a gluten-free diet for a few months to see if any of your symptoms go away, and if so, perhaps just stay gluten-free.

[Dawn s D]

Thanx for ur reply.could certain medications raise ttg iga?a nurse said it was possible?would non celiac gluten sensitivity raise ttg iga?the colorectal surgeon said he could see 2 separate areas of inflammation but biopsy said non found?he also said to continue on gluten until told otherwise which I don't know how long til I see gastroenteritis.I don't have much confidence in nhs no more due to previous issues.

[Scott Adams]

tTG tests are very specific for celiac disease, and I doubt your levels would be high due to anything else other than either non-celiac gluten sensitivity or celiac disease. Did they say how long it will take before you get an endoscopy? Normally you need to be eating around 2 slices of wheat bread daily before an endoscopy. 

[Dawn s D]

Hi Scott.i had gastroscopy and colonoscopy.the biopsies they took was 2 from stomach and 4 from D2.they came back as showing nothing.not even inflammation that was seen on camera?he said looks like h pylori and bilary gastritis but nothing shown on biopsy.i had coloscopy as had faecal calprotectin level of 775 <50 normal range.the colorectal surgeon took biopsies while doing the colonoscopy.he said in report that he doesn't know why my bloods are showing ttg iga but nothing on biopsy.he said he not expert in that area and handing me back to gastroenteritis and my gp for faecal calprotectin levels??I got to wait now for gastroenteritis which is wks away.the  nurse said it could be medication that's raised my ttg iga?

[Scott Adams]

Did your nurse say that any medications you are currently taking could cause a positive tTG test result? If so, which medication? 

Again, the tTG test is very specific for celiac disease, and it is unfortunate that they did not also take biopsies for celiac disease when you did your upper GI.

You may want to discuss with your doctor whether you could go on a gluten-free diet now, but start eating 2 slices of wheat bread daily at least 2 weeks prior to your endoscopy. It's possible that you might see your symptoms go away while gluten-free, and if so, that would be another indicator that you have celiac disease or NCGS.

More info about the diet:

 

[Dawn s D]

She never said.tried to Google but not coming up with anything about certain  medications.The biopsies that they took before of stomach an D2 sufficient for celiac?my gp not much use.he said wait til I see gastroenteritis as hes not an expert on it.

[Scott Adams]

The biopsies for celiac disease would need to have been done in your duodenum and not your stomach, and only they could answer whether or not they did this, but it sounds like they did not since they mentioned the need to do this.

[Holycow]

On 2/8/2023 at 8:13 AM, Dawn s D said:

Hi.i have just had my biopsy results through.says all normal.during colonoscopy they said bilary gastritis and what looks like h pylori due to inflammation present?the biopsy says no histological evidence of inflammation infection or celiac?what happens next?he said the findings are contradicts the bloods.he is advising his colleague and handing me back to  gp?what next?

Many things can cause of a falsely elevated TTG IGA including other autoimmune disease and infection.  Celiac blood tests are good but not perfect, so the assesment of no active celiac at this time is probably accurate.

[Scott Adams]

Actually TTG IGA tests, when done according to protocol, are about 98% accurate at diagnosing celiac disease.