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mrna vaccines reduce bifidobacteria in gut


Megawisdumb

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Megawisdumb Apprentice

Locally, since Covid it seems to me a larger portion of the population has celiac.   Getting a loaf of Schar bread at Publix is like winning the lotto.   Yesterday, I read the article below and it seemed to connect the dots.  Prior to my two shots, I had zero gut issues and got along great with beer and pop-tarts.  Maybe coincidence, maybe not but it might have been the trigger for me in my late 50's.  Might try to load up on bifidobacteria for a few months and see if I can restore my gut bio to see what happens down the road.   I can dream. 

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Scott Adams Grand Master

Best to link to the actual study, which isn't about the vaccine, but is about SARS-CoV-2 PCR-positive patients...a big difference. It's important to get information about vaccines from a good source, and not a bad one. This study does not show that the vaccine causes this, but may happen in those with covid-19, and the more severe the case of covid-19, the lower the levels of Bifidobacterium.

https://bmjopengastro.bmj.com/content/9/1/e000871 

Quote

Results Compared with controls (n=20), severely symptomatic SARS-CoV-2-infected patients (n=28) had significantly less bacterial diversity (Shannon Index, p=0.0499; Simpson Index, p=0.0581), and positive patients overall had lower relative abundances of Bifidobacterium (p<0.0001), Faecalibacterium (p=0.0077) and Roseburium (p=0.0327), while having increased Bacteroides (p=0.0075). Interestingly, there was an inverse association between disease severity and abundance of the same bacteria.

Conclusion We hypothesise that low bacterial diversity and depletion of Bifidobacterium genera either before or after infection led to reduced proimmune function, thereby allowing SARS-CoV-2 infection to become symptomatic. This particular dysbiosis pattern may be a susceptibility marker for symptomatic severity from SARS-CoV-2 infection and may be amenable to preinfection, intrainfection or postinfection intervention.

 

Megawisdumb Apprentice

Thank you for the clarity.  Vaccine and virus both man-made imo.  If the virus lowered the bacteria level instead of the vaccine it would still account for a bump.  I’ve attempted to see if ICD10 celiac or DH jumped post outbreak but have not seen any high level metrics.

Scott Adams Grand Master

The vaccine is definitely man made, but the source of the virus is being debated by scientists. Regardless of the source, the science is clear that those who are vaccinated have less serious disease, and less risk of death from it, and if they have less serious disease it means they are less likely to suffer from the lower the levels of Bifidobacterium in the gut which can cause many other negative health issues.

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    • Scott Adams
      This is a very common question, and the most important thing to know is that no, Guinness is not considered safe for individuals with coeliac disease. While it's fascinating to hear anecdotes from other coeliacs who can drink it without immediate issues, this is a risky exception rather than the rule. The core issue is that Guinness is brewed from barley, which contains gluten, and the standard brewing process does not remove the gluten protein to a level safe for coeliacs (below 20ppm). For someone like you who experiences dermatitis herpetiformis, the reaction is particularly significant. DH is triggered by gluten ingestion, even without immediate gastrointestinal symptoms. So, while you may not feel an instant stomach upset, drinking a gluten-containing beer like Guinness could very well provoke a flare-up of your skin condition days later. It would be a gamble with a potentially uncomfortable and long-lasting consequence. Fortunately, there are excellent, certified gluten-free stouts available now that can provide a safe and satisfying alternative without the risk.
    • MogwaiStripe
      Interestingly, this thought occurred to me last night. I did find that there are studies investigating whether vitamin D deficiency can actually trigger celiac disease.  Source: National Institutes of Health https://pmc.ncbi.nlm.nih.gov/articles/PMC7231074/ 
    • Butch68
      Before being diagnosed coeliac I used to love Guinness. Being made from barley it should be something a coeliac shouldn’t drink. But taking to another coeliac and they can drink it with no ill effects and have heard of others who can drink it too.  is this everyone’s experience?  Can I drink it?  I get dermatitis herpetiformis and don’t get instant reactions to gluten so can’t try it to see for myself. 
    • trents
      NCGS does not cause damage to the small bowel villi so, if indeed you were not skimping on gluten when you had the antibody blood testing done, it is likely you have celiac disease.
    • Scott Adams
      I will assume you did the gluten challenge properly and were eating a lot of gluten daily for 6-8 weeks before your test, but if not, that could be the issue. You can still have celiac disease with negative blood test results, although it's not as common:  Clinical and genetic profile of patients with seronegative coeliac disease: the natural history and response to gluten-free diet: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606118/  Seronegative Celiac Disease - A Challenging Case: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441776/  Enteropathies with villous atrophy but negative coeliac serology in adults: current issues: https://pubmed.ncbi.nlm.nih.gov/34764141/  Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.
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