SCARED: What Do These Test Results Mean?

[JustGemi]

I just got two test results from bloodwork I recently did. According to my numbers, it's looking like Celiac disease but I cannot see my doctor until next month. Can this be true? My numbers are so elevated this is ALARMING!

Tissue Transglutamine 120.9

Gliadin Antibody  IGA/IGC 62.1

Please shed some light on my numbers....

 

[Scott Adams]

Welcome to the forum! 

Could you also post the reference ranges for your test results, unfortunately each lab has a different range, so there is no way to interpret your results without that info.

[JustGemi]

Where would I locate the reference ranges?  I'll take a look at my results again....

[trents]

The reference ranges are usually included in the data but they may be cryptically expressed. Just type in everything from the results as it appears in the form you have it. Put it all in a new post window. We'll unpack it for you.

Edited March 28, 2024 by trents

[JustGemi]

The Tissue Transglutaminase Iga:

It says at the top of the page....Normal range: below <15.0 U/mL 

The numbers on the top/left of chart start at 123, 122.121.120.119

 

My Results 120.9 U/mL HIGH

___________________________________________________________________

The Gliadin AB Iga:

It says at the top of the page....Normal range: below <15.0 U/mL 

The numbers on the top/left of chart start at 64,63,62,61,60

My Results 62.1 U/mL HIGH

 

 

[Scott Adams]

So if the normal range for your tests is below 15.0 U/mL, and your results are 120.9 U/mL HIGH, it definitely looks like you could have celiac disease. Your doctor may want to schedule an endoscopy to confirm this, but with such high results it is also possible that the diagnosis might be made on your blood test results alone (more info on that is below).

This article might be helpful. It breaks down each type of test, and what a positive results means in terms of the probability that you might have celiac disease. 

In the Europe the new protocol for making a celiac disease diagnosis in children is if their tTg-IgA (tissue transglutaminase IgA) levels are 10 times or above the positive level for celiac disease.

According to the latest research, if the blood test results are at certain high levels that range between 5-10 times the reference range for a positive celiac disease diagnosis, it may not be necessary to confirm the results using an endoscopy/biopsy:

• Blood Test Alone Can Diagnose Celiac Disease in Most Children and Adults
• TGA-IgA at or Above Five Times Normal Limit in Kids Indicates Celiac Disease in Nearly All Cases
• No More Biopsies to Diagnose Celiac Disease in Children!

There are other things that may cause elevated tTg-IgA levels, but in general a reaction to gluten is the culprit:

 

 

[JustGemi]

Thank you! What do you recommend in the next 7 weeks until I see my Doctor?  Just start my Gluten free diet?

[trents]

No! Do not start the gluten free diet until you know whether or not you will be having an endoscopy/biopsy to verify the blood antibody test results. Starting gluten free eating ahead of either form of diagnostic testing can invalidate the results. You don't want to allow the villous lining of the small bowel to experience healing ahead of testing by removing gluten.

[JustGemi]

OK. Good to know. THANK YOU!