Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Second Biopsy To Show Improvement?


hjkmatthews

Recommended Posts

hjkmatthews Apprentice

Hi everyone. Well, it has been 6 months since my daughter was dx with Celiac, and she has a check up with her GI doctor next Friday. I was just wondering if she will be having another endoscopic procedure and biopsy scheduled to determine whether or not the gluten-free diet is helping her intestines to heal. If it is normal to have a second biopsy, when and how often? Thanks for any info you have!


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



lisabarella Apprentice

I have heard 6 months to a year for the 2nd one. I had the first July 18 03 and the second May 25th 04. It is helpful since they can see if the gluten free diet is working. I am not an expert, but that is what my dr advised.

Lisa

JsBaby-G Newbie

After my initial biopsy I had two more, one a year later and the other 2 years later. They just wanted to make sure I wasn't inadvertantly ingesting gluten.

Hope that helps!!

  • 2 weeks later...
Guest shar4

Hi all, I haven't been here in a while, but I had a 2nd biopsy yesterday, and I was told this morning that there are still findings of inflammation consistent with sprue. I was very disappointed, since I am as gluten free as I know how to be, but I am thinking that this still may be an improvement, since the first EGD showed a tremendous amount of damage. I was told at that time, that everything she touched with the instrument caused me to bleed.

I know, I know, all this damage didn't occur in a day, so I guess I should have expected this, but I am feeling so much better, that I had assumed that I was all healed inside.

Anyway, more details as they become available.

And thanks for listening to me whine.

Sharon ;)

lovegrov Collaborator

More and more the standard is to avoid the second endoscopy. Negative or improved follow-up blood tests and improvement on the diet are now considered proof you're getting better and the villi have healed. If you DO have the second one, it should be more like a year after starting, but I personally wouldn't do it.

richard

celiac3270 Collaborator

Two celiac friends (not on board) have not had second biopsies......I've heard no mention of one for me.

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      131,685
    • Most Online (within 30 mins)
      7,748

    tdouglas2901
    Newest Member
    tdouglas2901
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Scott Adams
      I'd go with a vodka tonic, but that's just me😉
    • Rejoicephd
      That and my nutritionist also said that drinking cider is one of the worst drink choices for me, given that I have candida overgrowth.  She said the combination of the alcohol and sugar would be very likely to worsen my candida problem.  She suggested that if I drink, I go for clear vodka, either neat or with a splash of cranberry.   So in summary, I am giving ciders a rest.  Whether it's a gluten risk or sugars and yeast overgrowth, its just not worth it.
    • Inkie
      Thank you for the information ill will definitely bring it into practice .
    • Scott Adams
      While plain, pure tea leaves (black, green, or white) are naturally gluten-free, the issue often lies not with the tea itself but with other ingredients or processing. Many flavored teas use barley malt or other gluten-containing grains as a flavoring agent, which would be clearly listed on the ingredient label. Cross-contamination is another possibility, either in the facility where the tea is processed or, surprisingly, from the tea bag material itself—some tea bags are sealed with a wheat-based glue. Furthermore, it's important to consider that your reaction could be to other substances in tea, such as high levels of tannins, which can be hard on the stomach, or to natural histamines or other compounds that can cause a non-celiac immune response. The best way to investigate is to carefully read labels for hidden ingredients, try switching to a certified gluten-free tea brand that uses whole leaf or pyramid-style bags, and see if the reaction persists.
    • Scott Adams
      This is a challenging and confusing situation. The combination of a positive EMA—which is a highly specific marker rarely yielding false positives—alongside strongly elevated TTG on two separate occasions, years apart, is profoundly suggestive of celiac disease, even in the absence of biopsy damage. This pattern strongly aligns with what is known as "potential celiac disease," where the immune system is clearly activated, but intestinal damage has not yet become visible under the microscope. Your concern about the long-term risk of continued gluten consumption is valid, especially given your family's experience with the consequences of delayed diagnosis. Since your daughter is now at an age where her buy-in is essential for a gluten-free lifestyle, obtaining a definitive answer is crucial for her long-term adherence and health. Given that she is asymptomatic yet serologically positive, a third biopsy now, after a proper 12-week challenge, offers the best chance to capture any microscopic damage that may have developed, providing the concrete evidence needed to justify the dietary change. This isn't about wanting her to have celiac; it's about wanting to prevent the insidious damage that can occur while waiting for symptoms to appear, and ultimately giving her the unambiguous "why" she needs to accept and commit to the necessary treatment. This article might be helpful. It breaks down each type of test, and what a positive results means in terms of the probability that you might have celiac disease. One test that always needs to be done is the IgA Levels/Deficiency Test (often called "Total IGA") because some people are naturally IGA deficient, and if this is the case, then certain blood tests for celiac disease might be false-negative, and other types of tests need to be done to make an accurate diagnosis. The article includes the "Mayo Clinic Protocol," which is the best overall protocol for results to be ~98% accurate.    
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.