Anyone Read This Book

[confused]

From "Gluten sensitivitiy as a neurological Illness" by M Hadjivassiliou, R A Grunewald, G A B Davies-Jones:

"Within the group of patients with neurological disease and gluten sensitivity (defined by the presence of anti-gliadin antibodies) we have found a similar HLA association to that seen in patients with celiac disease: 70% of patients have the HLA DQ2 (30% in the general population), 9% have the HLA DQ8, and the remainder have HLA DQ1. The finding of an additional HLA marker (DQ1) seen in the remaining 20% of our patients may represent an important difference between the genetic susceptibility of patients with neurological presentation to those with gastrointestinal presentation within the range of gluten sensitivity."

I just wanted to know if anyone read this book, I am really interested in what he has to say about all of this.

So is it possible one day that they will inclute DQ! as a gene for celiac i have found many other articles of people with DQ1 who test positive celiac in blook work or biopsy.

What does eveyone else think?

paula

[larry mac]

deleted/lm

[happygirl]

From "Gluten sensitivitiy as a neurological Illness" by M Hadjivassiliou, R A Grunewald, G A B Davies-Jones:

"Within the group of patients with neurological disease and gluten sensitivity (defined by the presence of anti-gliadin antibodies) we have found a similar HLA association to that seen in patients with celiac disease: 70% of patients have the HLA DQ2 (30% in the general population), 9% have the HLA DQ8, and the remainder have HLA DQ1. The finding of an additional HLA marker (DQ1) seen in the remaining 20% of our patients may represent an important difference between the genetic susceptibility of patients with neurological presentation to those with gastrointestinal presentation within the range of gluten sensitivity."

I just wanted to know if anyone read this book, I am really interested in what he has to say about all of this.

So is it possible one day that they will inclute DQ! as a gene for celiac i have found many other articles of people with DQ1 who test positive celiac in blook work or biopsy.

What does eveyone else think?

paula

Dr. H is one of the (if not THE) leading researcher in terms of gluten/neurological. His work is often cited by the other "big" Celiac researchers. There is evidence that there are gluten problems that don't cause GI damage, but instead 'damage' us neurologically (similar to how DH affects our skin).

Can you post the other articles you have found about DQ1 people? I would apprecaite it.

[confused]

Your confused? I can't even understand the authors name, much less what you said. And what does Dairy Queen have to do with Celiac?

best reagrds, lm

Sorry i meant DQ1 gene, some of my keys on my keyboard are stuck.

I was just saying do u think that someday there will be more genes that show celiac besides dq2 and dq8,

paula

[confused]

Dr. H is one of the (if not THE) leading researcher in terms of gluten/neurological. His work is often cited by the other "big" Celiac researchers. There is evidence that there are gluten problems that don't cause GI damage, but instead 'damage' us neurologically (similar to how DH affects our skin).

Can you post the other articles you have found about DQ1 people? I would apprecaite it.

I will go threw all my articles i have saved tommorow and post them.

So have you read a lot of his work?

paula

[Nantzie]

This is actually not a book (that I know of anyway). It's an article in a medical journal, which you can usually look at a small excerpt of (an abstract) on www.pubmed.gov. Which is a neat site to look at if you're into medical stuff.

This one was published in the Journal of Neurology and Neurosurgery in May 2002. I was actually trying to look at this study a couple months ago on pubmed, but it's one of the ones they don't have an abstract for .

DQ1 seems to be one of the most common non-celiac genes around here. So that study saying that DQ1 may make up 20% of people with celiac, but just with different symptoms, makes SOOO much sense doesn't it? I have two copies of DQ1, subtype 6. I had GI symptoms for 18 years, and neuro symptoms for about three years.

It's frustrating that a study that came out almost five years ago hasn't seeped into the knowledge of the medical community. But then again, many of them don't know much about what to look for in classic cases either.

I think that's why message boards like this one are so important. Without regular people exchanging information, we'd all be sunk.

Edited:

I just did a search and found this site, which is by one of our members I believe -

Open Original Shared Link

On there, she has a link to the full text article of the study you mentioned

Open Original Shared Link

Here's the main page of her site - Open Original Shared Link

Very informative. Lots of information. I had come across her page a long time ago, but lost the bookmark.

Nancy

[confused]

This is actually not a book (that I know of anyway). It's an article in a medical journal, which you can usually look at a small excerpt of (an abstract) on www.pubmed.gov. Which is a neat site to look at if you're into medical stuff.

This one was published in the Journal of Neurology and Neurosurgery in May 2002. I was actually trying to look at this study a couple months ago on pubmed, but it's one of the ones they don't have an abstract for .

DQ1 seems to be one of the most common non-celiac genes around here. So that study saying that DQ1 may make up 20% of people with celiac, but just with different symptoms, makes SOOO much sense doesn't it? I have two copies of DQ1, subtype 6. I had GI symptoms for 18 years, and neuro symptoms for about three years.

It's frustrating that a study that came out almost five years ago hasn't seeped into the knowledge of the medical community. But then again, many of them don't know much about what to look for in classic cases either.

I think that's why message boards like this one are so important. Without regular people exchanging information, we'd all be sunk.

Edited:

I just did a search and found this site, which is by one of our members I believe -

Open Original Shared Link

On there, she has a link to the full text article of the study you mentioned

Open Original Shared Link

Here's the main page of her site - Open Original Shared Link

Very informative. Lots of information. I had come across her page a long time ago, but lost the bookmark.

Nancy

Nancy thank you so much for all that information. I found it very informative. If you ever find any other articles will you let me know. I want to learn as much on the medical side as I can. I took lots of psychology classes, and how the brain works and so forth in college, and it always fascinated me. It is sad to say i dont remember much from the classes over 10 years ago, and i doubt we even talked about celiac disease anyway. I was going to call one of my old professors today, we still talk from time to time and see if he knows of any articles.'

paula