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- trents replied to mike101020's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms3EMA Result
Let me hasten to add that if you will be undergoing an endoscopy/biopsy, it is critical that you do not begin efforts to reduce gluten beforehand. Doing so will render the results invalid as it will allow the small bowel lining to heal and, therefore, obscure the damage done by celiac disease which is what the biopsy is looking for. -
- Scott Adams replied to Mary D63's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease21Violent reaction to gluten after going gluten-free?
This article, and the comments below it, may be helpful: -
- Scott Adams replied to JudyLou's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms12
Seeking advice on potential gluten challenge
That’s a really tough situation. A few key points: as mentioned, a gluten challenge does require daily gluten for several weeks to make blood tests meaningful, but negative tests after limited exposure aren’t reliable. Dermatitis herpetiformis can also be tricky to diagnose unless the biopsy is taken from normal-looking skin next to a lesion. Some people wit... -
- Lotte18 commented on Scott Adams's article in Diagnosis, Testing & Treatment6A Future Beyond the Gluten-Free Diet? Scientists Test a New Cell Therapy for Celiac Disease (+Video)
Hi Scott, Can you let us know where this study was done? Is it a private pharma study? A university study? Was it done here in the US or abroad? I'm not a subscriber to Science.org so I don't think I can access that info. Many thanks.- celiac disease
- cell therapy
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- Greymo replied to Mary D63's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease21Violent reaction to gluten after going gluten-free?
https://celiac.org/glutenexposuremarkers/ yes, two hours after accidents ingesting gluten I am vomiting and then diarrhea- then exhaustion and a headache. see the article above- There is research that shows our reactions.- 1
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By Scott Adams · Posted
That’s a really tough situation. A few key points: as mentioned, a gluten challenge does require daily gluten for several weeks to make blood tests meaningful, but negative tests after limited exposure aren’t reliable. Dermatitis herpetiformis can also be tricky to diagnose unless the biopsy is taken from normal-looking skin next to a lesion. Some people with celiac or DH don’t react every time they’re exposed, so lack of symptoms doesn’t rule it out. Given your history and family cancer risk, this is something I’d strongly discuss with a celiac-experienced gastroenterologist or dermatologist before attempting a challenge on your own, so risks and benefits are clearly weighed. -
https://celiac.org/glutenexposuremarkers/ yes, two hours after accidents ingesting gluten I am vomiting and then diarrhea- then exhaustion and a headache. see the article above- There is research that shows our reactions.
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Concerning the EMA positive result, the EMA was the original blood test developed to detect celiac disease and has largely been replaced by the tTG-IGA which has a similar reliability confidence but is much less expensive to run. Yes, a positive EMA is very strong evidence of celiac disease but not foolproof. In the UK, a tTG-IGA score that is 10x normal or greater will often result in foregoing the endoscopy/biopsy. Weaker positives on the tTG-IGA still trigger the endoscopy/biopsy. That protocol is being considered in the US but is not yet in place.
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Welcome to the celiac.com community, @mike101020! First, what was the reference range for the ttg-iga blood test? Can't tell much from the raw score you gave because different labs use different reference ranges. Second, there are some non celiac medical conditions, some medications and even some non-gluten food proteins that can cause elevated celiac blood antibodies in some individuals. The most likely explanation is celiac disease but it is not quite a slam dunk. The endoscopy/biopsy is considered the gold standard for celiac disease diagnosis and serves as confirmation of elevated blood antibody levels from the blood testing.
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By Wheatwacked · Posted
Vitamin D status in the UK is even worse than the US. vitamin D is essential for fighting bone loss and dental health and resistance to infection. Mental health and depression can also be affected by vitamin D deficiency. Perhaps low D is the reason that some suffer from multiple autoimmune diseases. In studies, low D is a factor in almost all of the autoimmune diseases that it has been studied in. Even while searching for your diagnosis, testing your 25(OH)D status and improving it my help your general wellness. Vitamin D Deficiency Affects 60% in Britain: How to Fix It?
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