Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Confused With Gene Test Results

Luisa2552

Recommended Posts

Luisa2552 Apprentice
Luisa2552
Posted

I got my HLA DQ2 and DQ8 tests and I'm not sure what they mean. I do have an appt. with my GI doc. next week but I thought I'd ask here first.

Even though DQ2 and DQ8 were requested, the tests listed say HLA-DQB1 02 (DQ2)

HLA-DQB1 05 (DQ5)

Both have a * after them which indicates 'out of range'. There is no range given.

What is that ? I've waited 3 weeks for this?

I'm guessing I don't have either gene so it didn't register on their test??

Anyone else get results like this? These tests were blood tests pulled at a local lab and run by Quest Diagnostics in VA.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


EBsMom Apprentice
EBsMom
Posted
Even though DQ2 and DQ8 were requested, the tests listed say HLA-DQB1 02 (DQ2)

HLA-DQB1 05 (DQ5)

It appears as though you have the DQ2 (a celiac gene) and DQ5 (a/k/a DQ1, subtype 5.) The DQ1 is not one of the main genes predisposing to celiac disease, but many here have it (or have 2.) Enterolab calls DQ1 a "gluten sensitivity" gene. There is no "range" for gene results. They just tell you which 2 copies you have, as above.

Rho

neesee Apprentice
neesee
Posted

I found this in Dr Green's book.

HLA-DQ2 is encoded by alleles DQA1*05 and DQB*02.

DQ8 is encoded by alleles DQB1*0302 and DQA1*03.

I hope this helps.

neesee

mftnchn Explorer
mftnchn
Posted

Are you saying these were the results or the tests requested?

Luisa2552 Apprentice
Luisa2552
Posted
  • Author
Are you saying these were the results or the tests requested?

Those were the results. I've done a bunch of reading and I guess I have the DQ2 and DQ5. I know the DQ2 is for Celiac and I'm not sure what the DQ5 is about. Don't you have to have BOTH DQ2 and DQ8 to be celiac disease? It's all so confusing :(

And by the way, my total IgA was normal......

Darn210 Enthusiast
Darn210
Posted

No, you only need one and there are a small percentage that don't even need one. DQ2 is the more common one and just because you have it, doesn't mean that you have (or will get) Celiac Disease. It means you are genetically at risk - but so is about 39% of the population (based on my son's gene test).

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      130,051
    • Most Online (within 30 mins)
      7,748
    levizagepro
    Newest Member
    levizagepro
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Scott Adams
      Pepsid alternative

      By Scott Adams · Posted

      It seems crazy to me that even when you call a manufacturer they can't, in this day and age, answer the simple question about what exactly is in their product!!
    • Stephanie Wakeman
      Is it common to develop a wheat allergy in addition to Celiac Disease?

      By Stephanie Wakeman · Posted

      Thank you so much for your response! It's been a challenging journey with this condition! 
    • milana
      Pepsid alternative

      By milana · Posted

      Thank you very much for your response. Since I got this advice I called Pepsid manufacturer and they could not give a definite answer. Basically,  there is no final testing and they do not guarantee anything. So I went and got farmotidine from Wagmans that was marked gluten-free and also our pediatrician gave us a prescription for farmotidine that was also gluten-free. So there are other options there thankfully. In case someone will come across of this dilemma.
    • Diana Swales
      Recently qualified Nutritionist looking for support

      By Diana Swales · Posted

      A nutritionist typically focuses on general wellness, lifestyle guidance, and preventative health. A dietician allowed to provide medical nutrition therapy. When i was diagnosed there was zero support and few dieticians and Dr understood celiac disease.  I typically guide a newly diagnosed celiac to a whole food diet to easily transition to the gluten free lifestyle  
    • Scott Adams
      gluten-free self diagnosed journey so far as well as what triggers. Eye crying like peeling onions?

      By Scott Adams · Posted

      Your gluten-free journey sounds like a lot of trial and error—especially working in a deli where gluten exposure is constant! The eye-watering issue could be an airborne gluten sensitivity (like flour dust irritating your eyes) or even a mild wheat allergy, since you’re around it daily. A daily antihistamine (like Claritin or Zyrtec) might help if it’s allergy-related, but avoiding airborne gluten as much as possible (masking, washing hands/face often) is key. It’s great you’re tracking triggers—high-fiber foods and certain gluten-free substitutes (like those tortillas or PB pretzels) can sometimes cause similar symptoms due to additives or digestive adjustments. For travel, pack safe snacks (protein bars, nuts) and research gluten-free translation cards for Aruba. On flights, opt for packaged gluten-free meals or eat beforehand. Many gluten-free foods and baking mixes contain xanthan gum or other gums like guar gum. Although they are both gluten-free, they may cause IBS-type issues in some people with celiac disease or gluten sensitivity:   You’re doing all the right prep—trust your research and enjoy your trips! 
×
×
  • Create New...