Need Experiences/opinions

[momof2sn]

Hello All,

Everyone here has always been such a great help so I have some more questions.

My daughter is the only celiac in the family. My hubby carries the HLA-DQ8 gene, but has a negative panel test. My son who is NOT celiac had an endoscopy for EE. The esophagus was better, but the intestine had red bumps all over. She said it could be possible celiac. Well, he had a negative panel a couple of months ago. ( he was suppose to have the celiac genetic test and our lab messed up AGAIN!) She did a biopsy of the area. He has no vomitting, diarrhea or constipation. She also wants to do an endoscopy on my hubby now. He has no symptoms either and as I said a negative panel. He does have alot of mucous production during eating and has to blow his nose often. Sometimes that is followed up by sneezing. The doctor said this could be his only symptom. Any thoughts?? Can someone have celiac with no symptoms and a negative panel. Can the doc tell if is celiac with a biopsy??

I appreciate any help!!

momof2sn

[happygirl]

Hello All,

Can someone have celiac with no symptoms and a negative panel.

Yes. What blood tests were done?

Silent Celiac is now believed to be MORE common than "classic" (i.e., symptomatic) Celiac. Presence or absence of symptoms, unfortunately, can't rule in/rule out Celiac alone.

Can the doc tell if is celiac with a biopsy??

Usually. The purpose of the biopsy is to rule in/rule out Celiac. It is recommended that multiple biopsies (4-6+) are taken from multiple locations to increase the accuracy rate, as Celiac can be a patchy disease.

[momof2sn]

Yes. What blood tests were done?

Silent Celiac is now believed to be MORE common than "classic" (i.e., symptomatic) Celiac. Presence or absence of symptoms, unfortunately, can't rule in/rule out Celiac alone.

Usually. The purpose of the biopsy is to rule in/rule out Celiac. It is recommended that multiple biopsies (4-6+) are taken from multiple locations to increase the accuracy rate, as Celiac can be a patchy disease.

The celiac genetic testing was done. His pulmonoligist and allergist ordered nearly every food and enviromental blood test as well as immune definicy. I think the GI also does a nutrition test. They took 9 tubes out of the poor guy....they couldn't do it while he was under either. The GI doc mentioned she may have to check his panel every 6 months for awhile. I am concerned about the biopsy because, my daughter the silly, her biopsy was negative!!! Her intestine was visually inflammed and no red bumps like my sons.

momof2sn