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Celiac Disease And Small Intestine Bacterial Overgrowth (Sibo)


willabec

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willabec Contributor

just checking to see who out there has both, celiac disease and sibo and which one was diagnosed first?? thanks!

  • 1 month later...

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Luv2Run Newbie

As part of a work-up for chronic diarrhea, I was diagnosed with SIBO. Symptoms did not improve following a couple of different courses of antibiotics, and a second breath test also showed SIBO. Another round of antibiotics was started, but no improvement. Despite having had 2 previous small bowel biopsies 10-12 years ago which showed severe villous atrophy (at that time my only symptom was severe anemia), I've been told by 4 different physicians that I do not have celiac disease since my blood tests are all normal. However, I recently consulted with celiac specialist (although he only treats children) and told that I do indeed have celiac disease. Started the gluten-free diet and in 4 weeks, GI symptoms cleared, only to return 3-4 weeks later despite close adherance to the gluten-free diet. Now I'm wondering if the SIBO has returned, or if I have pancreatic insufficiency. Perhaps the reason I didn't respond to antibiotics at that time was that I was consuming gluten, not realizing that I had celiac disease. This is such a complex disease!

  • 1 year later...
Gutsy Girl Rookie

Was diagnosed with Celiac 2010 (had started gluten-free diet 100 percent strict in mid-2009), and in 2011 was diagnosed with SIBO. Lived almost all my life with chronic diarrhea until several months after going gluten-free. Then after a few months, I had my first run-ins with constipation which was a new animal to me altogether. Its gotten worse and worse and now i have full-blown SIBO with methane producing bacteria (constipation-causing type...hydrogen producing bacteria causes diarrhea usually). celiac disease opens you up to getting SIBO. Yes, its very complex.

peeptoad Apprentice

I need to preface this by saying that I am not a diagnosed celiac. I have a definite sensitivity to gluten though.

I was diagnosed with SIBO a few years ago, took rifaximin (the typically prescribed antibiotic) and the overgrowth went away. Then it came back and I did not have the same improvement with the AB course. And then it came back again, and I began to investigate other possible causes for my problems.

One of the predisposing factors for SIBO is autoimmune disease, so people with diabetes, Hashimoto's, celiac, etc. are more likely to wind up with an overgrowth at some point.

ArtNest Newbie

I have been positively diagnosed with SIBO via hydrogen breath test & endoscopy. Biopsy also showed positive results for celiac but blood tests are negative due to IgA deficiency- I have a rare case of having no IgA at all; classified as an auto-immune disease that can lead to celiac. My doctor believes I have both Celiac & SIBO and I agree- I can not tolerate any gluten whatsoever !

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    • trents
      Let me hasten to add that if you will be undergoing an endoscopy/biopsy, it is critical that you do not begin efforts to reduce gluten beforehand. Doing so will render the results invalid as it will allow the small bowel lining to heal and, therefore, obscure the damage done by celiac disease which is what the biopsy is looking for.
    • Scott Adams
      This article, and the comments below it, may be helpful:    
    • Scott Adams
      That’s a really tough situation. A few key points: as mentioned, a gluten challenge does require daily gluten for several weeks to make blood tests meaningful, but negative tests after limited exposure aren’t reliable. Dermatitis herpetiformis can also be tricky to diagnose unless the biopsy is taken from normal-looking skin next to a lesion. Some people with celiac or DH don’t react every time they’re exposed, so lack of symptoms doesn’t rule it out. Given your history and family cancer risk, this is something I’d strongly discuss with a celiac-experienced gastroenterologist or dermatologist before attempting a challenge on your own, so risks and benefits are clearly weighed.
    • Greymo
      https://celiac.org/glutenexposuremarkers/    yes, two hours after accidents ingesting gluten I am vomiting and then diarrhea- then exhaustion and a headache. see the article above- There is research that shows our reactions.
    • trents
      Concerning the EMA positive result, the EMA was the original blood test developed to detect celiac disease and has largely been replaced by the tTG-IGA which has a similar reliability confidence but is much less expensive to run. Yes, a positive EMA is very strong evidence of celiac disease but not foolproof. In the UK, a tTG-IGA score that is 10x normal or greater will often result in foregoing the endoscopy/biopsy. Weaker positives on the tTG-IGA still trigger the endoscopy/biopsy. That protocol is being considered in the US but is not yet in place.
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