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Dq2 Heterozygote


enolah

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enolah Rookie

My daughter's saliva test from Prometheus came back yesterday. Her brief trial of gluten free (6 weeks) helped her pain but not her diarrhea. She has since gone back to a regular diet with one more month to go until her endoscopy. The GI doc wanted her to be back on gluten 2-3 months before the scope.

Dh asks why we're proceeding with the scope. I think we need to look for non-celiac causes to her symptoms.

In brief, her symptoms are: lots of gas and tummy rumbling

morning abdominal cramps and diarrhea

morning nausea but rarely vomiting

acid reflux improved on omeprazole

greasy, frothy stools with 2 abnormal fecal fat tests

endomysial antibody test negative 18 months ago and not repeated

weight loss

Feel free to weigh in with your opinions/advice.


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It's always a good idea to rule out non-celiac causes of symptoms with negative blood tests, especially if the diarrhea didn't go away. It is possible she was still getting gluten somewhere or needed longer to heal. She does have a lot of signs of celiac.

The genetic tests are not diagnostic, only an assessment of risk. Celiac is more likely in someone with DQ2 than the other inflammatory bowel diseases.

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