Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Dna Test Advice

ChristineSelhi

By ChristineSelhi
in Doctors

Recommended Posts

ChristineSelhi Rookie
ChristineSelhi
Posted

Hi All,

I got a DNA test back in 2004 that told me I was nonceliac. I just called to get the test results to really understand what the diagnosis was, because I have been gluten free ever since, and have had a number of nurses and doctors tell me that I still exhibit symptoms of the disease.

I tested negative for DQ2 and DQ8. Does this mean I do not have celiac? Also, I have heard a couple of different things about the percentage of people with celiac disease who have these genes. I have heard anything from 85%-99%. Any words of wisdom?

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


cassP Contributor
cassP
Posted

DQ2s and DQ8s make up the majority from what ive read, they're considered the "classic" genes... but just because you dont have those 2, doesnt mean you cant have celiac!

there's members on this forum with celiac and different genes. from what ive read, there's like 27 DQ genes that are linked to gluten sensitivity/intolerance. and it seems as tho doctors in Europe are ahead of the game as far as recognizing other DQ genes in Celiac.

but also, too, the genes are only part of it-

did you also get any antibodies tests?? or just the genes?

Kay DH Apprentice
Kay DH
Posted

I have a different issue. I have the HLA-DQ8 genetic marker, and oodles of symptoms that went away once I went gluten-free last fall. My celiac panel and endoscopy biopsy were negative for celiac, although the tests were flawed. Not all people diagnosed with celiac have HLA-DQ2 or DQ8; as the previous poster indicated, there are other probable genetic markers. There is very little research that has been conducted on celiac and gluten sensitivity. The symptoms are so varied and complex that it is very likely the genetic imprint is as well. It is frustrating not having a diagnosis, but it is important to trust how your body feels. The FDA just approved a new test for celiac that hopefully is more accurate than most of the current ones, especially for those of us that are gluten-free and will not do the gluten challenge.

ChristineSelhi Rookie
ChristineSelhi
Posted
  • Author

I had already started the gluten free diet by the time I could have any antibody tests done. I am so sensitive that I break out from just crumbs on a stick of butter, and I get sick for days from small CC, so I wasn't willing to go back on. So, I guess I have to live with what I got. Either way, I don't eat gluten. Thanks for your reply!

Coconut's mom Newbie
Coconut's mom
Posted

Can someone tell me where to get this DNA test?

Skylark Collaborator
Skylark
Posted

Can someone tell me where to get this DNA test?

If your insurance covers it your doctor can order it, but please understand that the genetic test is not diagnostic for celiac. It also does not rule it out. We don't know enough about the genetics yet, or what triggers celiac in people with the genes we think are involved. All that's known is that certain HLA-DQ alleles confer somewhat more risk for celiac disease than others.

Open Original Shared Link offers testing as does Open Original Shared Link I think you can also order it from Kimball. Open Original Shared Link They test for different subsets of the celiac genes, so you might read up some on the tests and decide what you want to know before you order.

  • 2 months later...
salexander421 Enthusiast
salexander421
Posted

The FDA just approved a new test for celiac that hopefully is more accurate than most of the current ones, especially for those of us that are gluten-free and will not do the gluten challenge.

What is this test called??

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,542
    • Most Online (within 30 mins)
      7,748
    Carol Zimmer
    Newest Member
    Carol Zimmer
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Jsingh
      Protein or fat?

      By Jsingh · Posted

      Hi,  I care for my seven year old daughter with Celiac. After watching her for months, I have figured out that she has problem with two kinds of fats- animal fat and cooking oils. It basically makes her intestine sore enough that she feels spasms when she is upset. It only happens on days when she has eaten more fat than her usual every day diet. (Her usual diet has chia seeds, flaxseeds, and avocado/ pumpkin seeds for fat and an occasional chicken breast.) I stopped using cooking oils last year, and when I reintroduced eggs and dairy, both of which I had held off for a few months thinking it was an issue of the protein like some Celiac patients habe mentioned to be the case, she has reacted in the same fashion as she does with excess fats. So now I wonder if her reaction to dairy and eggs is not really because of protein but fat.   I don't really have a question, just wondering if anyone finds this familiar and if it gets better with time.  Thank you. 
    • Chanda Richard
      High Cost of Gluten-Free Foods

      By Chanda Richard · Posted

      Hello, My name is Chanda and you are not the only one that gose through the same things. I have found that what's easiest for me is finding a few meals each week that last. I have such severe reactions to gluten that it shuts my entire body down. I struggle everyday with i can't eat enough it feels like, when I eat more I lose more weight. Make sure that you look at medication, vitamins and shampoo and conditioner also. They have different things that are less expensive at Walmart. 
    • petitojou
      Frequent nausea after gluten-free diet

      By petitojou · Posted

      Thank you so much! I saw some tips around the forum to make a food diary and now that I know that the community also struggles with corn, egg and soy, the puzzle pieces came together! Just yesterday I tried eating eggs and yes, he’s guilty and charged. Those there are my 3 combo nausea troublemakers. I’m going to adjust my diet ☺️ Also thank you for the information about MCAS! I’m from South America and little it’s talked about it in here. It’s honestly such a game changer now for treatment and recovery. I know I’m free from SIBO and Candida since I’ve been tested for it, but I’m still going to make a endoscopy to test for H. Pylori and Eosinophilic esophagitis (EoE). Thank you again!! Have a blessed weekend 🤍
    • knitty kitty
      Unusual bright yellow but odourless discharge

      By knitty kitty · Posted

      Yes, I, too, have osteoporosis from years of malabsorption, too.  Thiamine and magnesium are what keep the calcium in place in the bones.  If one is low in magnesium, boron, selenium, zinc, copper, and other trace minerals, ones bone heath can suffer.  We need more than just calcium and Vitamin D for strong bones.  Riboflavin B 2, Folate B 9 and Pyridoxine B 6 also contribute to bone formation and strength.   Have you had your thyroid checked?  The thyroid is important to bone health as well.  The thyroid uses lots of thiamine, so a poorly functioning thyroid will affect bone heath.  
    • Celiac50
      Unusual bright yellow but odourless discharge

      By Celiac50 · Posted

      That sounds so very likely in my case! I will absolutely ask my doctor on my next bone check coming up in March... Thanks a lot! 
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.