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Why So Many Cross-Reactive Foods? Is There Any End To This? And Do We Know Why We Are Becoming 'allergic' To So Many Other Foods?


Evangeline

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Evangeline Explorer

After reading the Celiac message board and plenty of Celiac medical articles, I know now that it is almost "normal" for Celiacs to be cross-reactive to corn, soy, rice, potatoes (or all nightshade plants), coffee, chocolate, sesame seeds and probably 100 other foods.

I myself have finally discovered I am corn, soy, dairy and nightshade intolerant. I also notice I experience a little inflammation and diarrhea on rice, avocados, onions, you name it. I also now seem to be allergic to most healthy greens (kale, spinach, broccoli, cauliflower, mustard greens, bok choi, and 20 others) because they make me feel EXTREMELY FATIGUED For 3 days after eating them.

I see many people are told to start rotational diets. I have been told this as well.

I understand the concept of intestinal permeability and why Celiacs are more prone to these sensitivities. I'm just wondering if we know WHY Celiacs who have been gluten-free for 10 years are still discovering they cannot eat rice, etc? Is it because almost half of Celiacs are soy, dairy and corn intolerant in the first place? And because they never removed those foods as they did the gluten, the intestinal permeability bacame worse causing more sensitivities?

Are these people ever able to eat broccoli and spinach again? Or do they forever have a reaction?

Or is the research about this disease still basically in its infancy and we really don't know if these people can ever eat rice or greens again?


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Evangeline Explorer

For example: Perhaps half of Celiacs can't eat ANY GRAINS? And because they keep all grains except for gluten in their diet, they become sensitive to other foods?

What is the cause behind all of these food sensitivities??

mushroom Proficient

Well, I am a believer in the leaky gut syndrome. As long as quantities of other foods are make their way into the blood stream in only a partially digested form, the body is going to recognize them as non-self and mount an attack on them as foreign invaders. Until your gut is healed this will continue, especially with continual exposure to these foods (and new ones as well) if you eat too much of them. And it is a bit of a vicious catch-22 cycle, because as we eliminate more foods our diets become more limited. We have to constantly look for different foods to add to our diet so that we don't become stuck on a mono-diet. But hey, new foods are fun, and some of them are yum. :) I almost bought some taro root yesterday, but then decided I am too busy this week to figure out what to do with it. Maybe next week :P

knf Newbie

The details are different, but this is exactly what I am dealing with lately too.

I have also become a huge believer that a leaking gut can change everything up. For me, I think this explains why I am suddenly sensitive to so many things that were ok for the first 10 years of being gluten free.

What have people done to successfully heal guts? I know I need to identify and avoid the offending foods. I think probiotics are helping me a lot. I have heard fermented foods can help, but could use some advice there. Without dairy or soy, I don't have the options of yogurt or miso.

Anything else I should try?

mushroom Proficient

The truly fermented cabbage is supposed to be good, not just the sauerkraut in a can. I think you can get it from a health food store. Other posters on here have touted the benefits of L-glutamine in healing the gut. You also need to make sure all your nutrients are at optimal levels - it may be a while since you had these tested.

Evangeline Explorer

I used to believe that we needed to add supplements to our diets to heal the leaky gut syndrome, but I now believe there is an underlying reason why the intestines and bodies of Celiacs are not healing by itself like any other injury - efficiently and quickly. Obviously, there is a problem that everyone is over looking. As I research the topic, it is obvious that most Celiacs learn they are intolerant (not sensitive!) to corn and soy. There are so many medical articles that state that many Celiacs still have intestinal damage after adhering to a 10-year gluten free diet according to biopsies. I am beginning to wonder if Celiacs should not only avoid gluten, but also most or all grain? There is a reason people are still developing allergies and dealing with leaky gut many years after removing gluten.

Some theories:

Grains were only brought into our diet ten thousand years ago, that was ~300 generations ago. They weren't intended by nature to be eaten in such huge quantities or even in moderate quantities. The seeds are too tiny to spend all day picking up a shaft to eat the seeds all day. It would have been much more efficient to fill the diet with tubers (yams, squash, sweet potatoes, etc.) I am wondering if in the end, researchers will suggest that Celiacs avoid grains entirely?

Also, I also read that the Genetically Modified foods (foods where scientists have changed the DNA structure of a grain in a laboratory) definitely increase allergies and leaky gut syndrome. Villages where genetically modified crops were exclusively grown by Monsanto experienced a 500% increase in allergies during the grains pollination season. These genetically modified crops have increased to almost 60% of our foods in the last 10 years. Some researchers have warned that people with immune disorders and intestinal disorders, such as Celiac Disease, might be even more at risk by being affected by GM foods. These foods are so far gluten, corn, soy, sugar and some zucchinis and yellow squash. GM ingredients are basically ubiquitous. They are in vitamins, supplements, ingredients like "citric acid" and "ascorbic acid."

So I am trying to think of REASONS why the Celiacs ARE NOT HEALING. Is it the GM foods? Is it because humans were not originally designed to eat grains? Hmmm...

ilikepie Apprentice

I don't have any answers to these questions. But it makes me feel SO much better knowing that other people are suffering through the same problems I am. I have been to so many doctor appointments, and not any kind of specialist can find (or is willing/interested in finding out)what is wrong with me. I feel like soon I won't be able to tolerate ANY foods.

I hope we all find our answers soon.


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Evangeline Explorer

I don't have any answers to these questions. But it makes me feel SO much better knowing that other people are suffering through the same problems I am. I have been to so many doctor appointments, and not any kind of specialist can find (or is willing/interested in finding out)what is wrong with me. I feel like soon I won't be able to tolerate ANY foods.

I hope we all find our answers soon.

I just read about Dr. Osborne's truly gluten-free diet. He claims that we react to the gluten in ALL the grains, not just the gliadin in wheat, barley, rye. If you are desperate, I would google for more info. So far I know he says that Celiacs can't have any grains in any products or animal products from grain-fed animals. I also found a blog by a really sick Celiac who tried his diet and took blood tests throughout the diet to monitor inflammation levels. His inflammation levels went from 33 to 2. Check out his grain-free diet result:

Open Original Shared Link

GFinDC Veteran

I saw a research article not long ago where they said babies who are milk intolerant and then switched to soy formula have a tendency to develop more food intolerances or allergies. So it seems like the soy causes a problem.

Evangeline Explorer

I read a study where calves were given soy formula and their intestinal villi were completely destroyed. I know many Celiacs who are soy intolerant, including myself. Also, soy helps cause a lot of depression for many Celiacs.

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    • Mmoc
      Thank you kindly for your response. I have since gotten the other type of bloods done and am awaiting results. 
    • Aretaeus Cappadocia
      I wanted to respond to your post as much for other people who read this later on (I'm not trying to contradict your experience or decisions) > Kirkland Signature Super Extra-Large Peanuts, 2.5 lbs, are labeled "gluten free" in the Calif Costcos I've been in. If they are selling non-gluten-free in your store, I suggest talking to customer service to see if they can get you the gluten-free version (they are tasty) > This past week I bought "Sliced Raw Almonds, Baking Nuts, 5 lbs Item 1495072 Best if used by Jun-10-26 W-261-6-L1A 12:47" at Costco. The package has the standard warning that it was made on machinery that <may> have processed wheat. Based on that alone, I would not eat these. However, I contacted customer service and asked them "are Costco's Sliced Almonds gluten free?" Within a day I got this response:  "This is [xyz] with the Costco Member Service Resolutions Team. I am happy to let you know we got a reply back from our Kirkland Signature team. Here is their response:  This item does not have a risk of cross contamination with gluten, barley or rye." Based on this, I will eat them. Based on experience, I believe they will be fine. Sometimes, for other products, the answer has been "they really do have cross-contamination risk" (eg, Kirkland Signature Dry Roasted Macadamia Nuts, Salted, 1.5 lbs Item 1195303). When they give me that answer I return them for cash. You might reasonably ask, "Why would Costco use that label if they actually are safe?" I can't speak for Costco but I've worked in Corporate America and I've seen this kind of thing first hand and up close. (1) This kind of regulatory label represents risk/cost to the company. What if they are mistaken? In one direction, the cost is loss of maybe 1% of sales (if celiacs don't buy when they would have). In the other direction, the risk is reputational damage and open-ended litigation (bad reviews and celiacs suing them). Expect them to play it safe. (2) There is a team tasked with getting each product out to market quickly and cheaply, and there is also a committee tasked with reviewing the packaging before it is released. If the team chooses the simplest, safest, pre-approved label, this becomes a quick check box. On the other hand, if they choose something else, it has to be carefully scrutinized through a long process. It's more efficient for the team to say there <could> be risk. (3) There is probably some plug and play in production. Some lots of the very same product could be made in a safe facility while others are made in an unsafe facility. Uniform packaging (saying there is risk) for all packages regardless of gluten risk is easier, cheaper, and safer (for Costco). Everything I wrote here is about my Costco experience, but the principles will be true at other vendors, particularly if they have extensive quality control infrastructure. The first hurdle of gluten-free diet is to remove/replace all the labeled gluten ingredients. The second, more difficult hurdle is to remove/replace all the hidden gluten. Each of us have to assess gray zones and make judgement calls knowing there is a penalty for being wrong. One penalty would be getting glutened but the other penalty could be eating an unnecessarily boring or malnourishing diet.
    • trents
      Thanks for the thoughtful reply and links, Wheatwacked. Definitely some food for thought. However, I would point out that your linked articles refer to gliadin in human breast milk, not cow's milk. And although it might seem reasonable to conclude it would work the same way in cows, that is not necessarily the case. Studies seem to indicate otherwise. Studies also indicate the amount of gliadin in human breast milk is miniscule and unlikely to cause reactions:  https://www.glutenfreewatchdog.org/news/gluten-peptides-in-human-breast-milk-implications-for-cows-milk/ I would also point out that Dr. Peter Osborne's doctorate is in chiropractic medicine, though he also has studied and, I believe, holds some sort of certifications in nutritional science. To put it plainly, he is considered by many qualified medical and nutritional professionals to be on the fringe of quackery. But he has a dedicated and rabid following, nonetheless.
    • Scott Adams
      I'd be very cautious about accepting these claims without robust evidence. The hypothesis requires a chain of biologically unlikely events: Gluten/gliadin survives the cow's rumen and entire digestive system intact. It is then absorbed whole into the cow's bloodstream. It bypasses the cow's immune system and liver. It is then secreted, still intact and immunogenic, into the milk. The cow's digestive system is designed to break down proteins, not transfer them whole into milk. This is not a recognized pathway in veterinary science. The provided backup shifts from cow's milk to human breastmilk, which is a classic bait-and-switch. While the transfer of food proteins in human breastmilk is a valid area of study, it doesn't validate the initial claim about commercial dairy. The use of a Dr. Osborne video is a major red flag. His entire platform is based on the idea that all grains are toxic, a view that far exceeds the established science on Celiac Disease and non-celiac gluten sensitivity. Extraordinary claims require extraordinary evidence, and a YouTube video from a known ideological source is not that evidence."  
    • Wheatwacked
      Some backup to my statement about gluten and milk. Some background.  When my son was born in 1976 he was colicky from the beginning.  When he transitioned to formula it got really bad.  That's when we found the only pediactric gastroenterologist (in a population of 6 million that dealt with Celiac Disease (and he only had 14 patients with celiac disease), who dianosed by biopsy and started him on Nutramegen.  Recovery was quick. The portion of gluten that passes through to breastmilk is called gliadin. It is the component of gluten that causes celiac disease or gluten intolerance. What are the Effects of Gluten in Breastmilk? Gliaden, a component of gluten which is typically responsible for the intestinal reaction of gluten, DOES pass through breast milk.  This is because gliaden (as one of many food proteins) passes through the lining of your small intestine into your blood. Can gluten transmit through breast milk?  
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