Results Of Blood Work

[tera200]

My family doctor ran a Celiac blood screen on my 6 year old daughter. The specialist said that the test were no longer used. She order another. The second was from a different lab on a different day. Should I have them run another test based on these results:

Tissue transglutaimin ases ab, IgA .3 (<7 Negative)

Gliadin Peptide Ab, IgG 21 (>10 Positive)

Gliadin Poptide Ab, IgA 1.4 (<7 Neg.)

(this lab put a paragraph about IgA deficiency and it stats and recommendations, but they did not specifically way she was dificient.)

The GI specialist said ignore the positive IgG and order this and we had to go to another lab:

IGG A, QN, S 189 (27-195 mg/dL)

In summary, 1-Is it best to test on the same day? 2-Does it seem like she might be IgA deficient? 3-Could the result indicated a non-celiac sensitivity?

Thanks

[lizard00]

I don't see where they did a total serum IgA test, which would indicate a deficiency or not. Am I missing it? Perhaps they ran it with the new panel?

[tera200]

I don't see where they did a total serum IgA test, which would indicate a deficiency or not. Am I missing it? Perhaps they ran it with the new panel?

This is all new to me. The first test was IgA...but I don't know how to tell if it total IgA. The full name of the last test was Immunoglobulin A, QN, Serum(ordered IGG A, QN Serum). I guess with one Positive, I wanted to explore if it could possibly mean anything. I was told not to worry about it, but I want to be thorough. Those are all the result I have with the names of each specific test done. Thanks for reading.

[lizard00]

The full name of the last test was Immunoglobulin A, QN, Serum(ordered IGG A, QN Serum).

If this is the total IgA serum, then it looks like there is no IgA deficiency.

[ravenwoodglass]

While the IGA was negative the IGG wasn't. After all testing is done a good strict trial of the diet would be a good thing as false negatives are common but false positives are not.

[tera200]

After reading reading information, I am finally starting to get it. I read that with only high IGG levels, it is likely that she is Gluten intolerant, and not Celiac. But I also read that the typical GI Dr will not think the results are significant, like her GI.

I have to have a doctor support a trial Gluten free diet becuase I am sure her father will not support the Gluten free diet with the urging of a docter because it is too hard. Even then, I just don't think he wll be able to do it. He can't even handle the diet and medication for her constipation.

My girl is on about 6 adult doses of laxatives a day...and even then, she is still constipated. It seems only to get worse over years of treatment, instead of better. (just a little vent over my frustration with the situation)

[ravenwoodglass]

After reading reading information, I am finally starting to get it. I read that with only high IGG levels, it is likely that she is Gluten intolerant, and not Celiac. But I also read that the typical GI Dr will not think the results are significant, like her GI.

I have to have a doctor support a trial Gluten free diet becuase I am sure her father will not support the Gluten free diet with the urging of a docter because it is too hard. Even then, I just don't think he wll be able to do it. He can't even handle the diet and medication for her constipation.

My girl is on about 6 adult doses of laxatives a day...and even then, she is still constipated. It seems only to get worse over years of treatment, instead of better. (just a little vent over my frustration with the situation)

That is a lot of laxatives for a little girl. You may want to seek a second opinion from another GI doctor or talk to her ped and see if you can get a 'doctors slip' for the need to try the diet. Chronic C is not unusual for us to deal with, I had it for years before the more typically thought of D set in. If she needs that much laxatives she is at a risk for impaction which is really not a pleasent thing to go through.

The diet isn't as hard as many think it is and most food in it's whole state is gluten free. Eggs, meats, chicken, rice, veggies and fruits etc would be examples. I hope you are able to talk her father into letting you do a trial of the gluten-free diet as she could be headed for some serious issues down the road if she needs to be on the diet and isn't. It is also possible that her tests are a false negative as that is even more common in children than adults. It took a long time for me to get diagnosed because I show false negatives on blood tests. You can see by my signature what can happen to someone when celiac or gluten intolerance are ignored.

[nicolebeth]

So sorry to hear about all that constipation! Aside from going gluten-free, I would recommend going dairy-free. I know of other kids who've had constipation issues and they've cleared up after dairy is eliminated. (My daughter, to a much milder extent, has constipation from dairy, most likely lactose intolerance--and we've know this since she first had cheese and yogurt as a baby.)

Good luck!