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Pathology Report


BellaBella

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BellaBella Rookie

A couple of days ago I posted a thread about my biopsy results.

One member suggested getting the pathology report and posting that here so that's what I'm doing now:

Material submitted:

Part A: second part duodenum

Diagnosis:

Normal duodenal mucosa. No abnormalities seen. No evidence of sprue is seen.

Gross description:

A) Received in a 10% neutral buffered formalin filled bottle labeled "second part duodenum" with patient's name and an accession number are multiple irregular fragments of soft tan tissue ranging in size from 0.3 x 0.2 x 0.2 cm to 0.5 x 0.2 x 0.1cm. All fragments are totally submitted in one cassette.

A: Sections show duodenal mucosa with intact villous architecture. No evidence of neoplasia and no significant inflammatory infiltrates. No infectious organisms are seen. There is no evidence of sprue.


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Bubba's Mom Enthusiast

It means they aren't seeing any damage or inflamation in the biopsies that were taken. They appear normal.

carecare Enthusiast

My biopsy came back clear too. I'm not bummed though...I'm still going to live gluten free because I know it makes me feel best. Good luck to you!

nora-n Rookie

So they did not count the IEL

BellaBella Rookie

So they did not count the IEL

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    • trents
      Let me hasten to add that if you will be undergoing an endoscopy/biopsy, it is critical that you do not begin efforts to reduce gluten beforehand. Doing so will render the results invalid as it will allow the small bowel lining to heal and, therefore, obscure the damage done by celiac disease which is what the biopsy is looking for.
    • Scott Adams
      This article, and the comments below it, may be helpful:    
    • Scott Adams
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    • Greymo
      https://celiac.org/glutenexposuremarkers/    yes, two hours after accidents ingesting gluten I am vomiting and then diarrhea- then exhaustion and a headache. see the article above- There is research that shows our reactions.
    • trents
      Concerning the EMA positive result, the EMA was the original blood test developed to detect celiac disease and has largely been replaced by the tTG-IGA which has a similar reliability confidence but is much less expensive to run. Yes, a positive EMA is very strong evidence of celiac disease but not foolproof. In the UK, a tTG-IGA score that is 10x normal or greater will often result in foregoing the endoscopy/biopsy. Weaker positives on the tTG-IGA still trigger the endoscopy/biopsy. That protocol is being considered in the US but is not yet in place.
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