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Celiac disease immunotherapy that would replace a gluten-free diet begins ... - MedCity News

Scott Adams

By Scott Adams
in Publications & Publicity

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Scott Adams Grand Master
Scott Adams
Posted

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MedCity News

The lead product from Cambridge, Massachusetts drug company ImmusanT is Nexvax2, an immunotherapy that uses a series of peptides to reprogram T cells triggered by gluten, a protein found in wheat, barley and rye, in patients with celiac disease.

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ravenwoodglass Mentor
ravenwoodglass
Posted

"Along with the drug, ImmusanT has developed a companion blood test to identify HLA-DQ2 celiac patients.

kittty Contributor
kittty
Posted

It sounds good, but the side effects from the early trials included nausea for almost half of the test subjects. I guess it's easy to live a full gluten lifestyle if you're too nauseous to eat anything.

pricklypear1971 Community Regular
pricklypear1971
Posted

"Along with the drug, ImmusanT has developed a companion blood test to identify HLA-DQ2 celiac patients.

GottaSki Mentor
GottaSki
Posted

Hmmm reprogramming my T cells so that I can "safely" ingest gluten -- interesting, but I'll stick with living gluten free.

Zonulin research to possibly aid in healing of our highly permeable small intestines along with research to produce enzymes that can aid in protecting our system from small amounts of gluten/CC while dining out are both more interesting to me than genetic manipulation for now.

My wish list for Celiac Disease research would include accurate testing for both Celiac Disease and Gluten Intolerance AND that those accurate tests be ordered by doctors in EVREY case that presents with gastrointestinal and autoimmune symptoms. It would have been very beneficial to have been diagnosed a few decades earlier. I remain hopeful that early diagnosis will come for others in the future -- of course prevention does not provide avenue for the production of new pharmaceutical products - so I may be waiting a very long time.

Guess I'll choose to focus on the fact that all research with regard to Celiac Disease adds some information to the puzzle and try to find a patience tree to pick some fruit off of - my supply seems to be running a bit low ;)

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    • trents
      how much gluten do I need to eat before blood tests?

      By trents · Posted

      I might suggest you consider buckwheat groats. https://www.amazon.com/Anthonys-Organic-Hulled-Buckwheat-Groats/dp/B0D15QDVW7/ref=sr_1_4_pp?crid=GOFG11A8ZUMU&dib=eyJ2IjoiMSJ9.bk-hCrXgLpHqKS8QJnfKJLKbKzm2BS9tIFv3P9HjJ5swL1-02C3V819UZ845_kAwnxTUM8Qa69hKl0DfHAucO827k_rh7ZclIOPtAA9KjvEEYtaeUV06FJQyCoi5dwcfXRt8dx3cJ6ctEn2VIPaaFd0nOye2TkASgSRtdtKgvXEEXknFVYURBjXen1Nc7EtAlJyJbU8EhB89ElCGFPRavEQkTFHv9V2Zh1EMAPRno7UajBpLCQ-1JfC5jKUyzfgsf7jN5L6yfZSgjhnwEbg6KKwWrKeghga8W_CAhEEw9N0.eDBrhYWsjgEFud6ZE03iun0-AEaGfNS1q4ILLjZz7Fs&dib_tag=se&keywords=buckwheat%2Bgroats&qid=1769980587&s=grocery&sprefix=buchwheat%2Bgroats%2Cgrocery%2C249&sr=1-4&th=1 Takes about 10 minutes to cook. Incidentally, I don't like quinoa either. Reminds me and smells to me like wet grass seed. When its not washed before cooking it makes me ill because of saponins in the seed coat. Yes, it can be difficult to get much dietary calcium without dairy. But in many cases, it's not the amount of calcium in the diet that is the problem but the poor uptake of it. And too much calcium supplementation can interfere with the absorption of vitamins and minerals in general because it raises gut pH.
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    • Scott Adams
      Question

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    • catnapt
      how much gluten do I need to eat before blood tests?

      By catnapt · Posted

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    • trents
      IBS-D vs Celiac

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      Welcome to the celiac.com community, @SilkieFairy! You could also have NCGS (Non Celiac Gluten Sensitivity) as opposed to celiac disease. They share many of the same symptoms, especially the GI ones. There is no test for NCGS. Celiac disease must first be ruled out.
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