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Iga Antibodies And Negative Test Results

cindylou7

By cindylou7
in Dermatitis Herpetiformis

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cindylou7 Apprentice
cindylou7
Posted

Can low (still within normal) IgA antibodies affect blood test and skin biopsies?

On another note, I've been faithful to gluten-free diet and haven't had any noticeable GI symptoms that would indicate accidental glutening, but I had a breakout of DH on my skin on my arm and a return of what I always thought of as acne on my neck. It's sort of like a cyst and similar to the ones on my bottom. The only thing different in my diet is an increase in pickles/pickle juice, and I recently gave blood. Iodine? I've never noticed a connection for me.

I still have tons of questions about gluten intolerance.

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squirmingitch Veteran
squirmingitch
Posted

Yes, low IgA antibodies can affect blood tests & skin biopsies. But the question is moot b/c you have been gluten free for quite some time now. Cindylou, nothing you do short of eating gluten for some time will give you any positive test results now ---- NOTHING.

DH can break out at any time EVEN though you have been eating gluten free for up to 2 years & EVEN longer --- some texts say up to 10 years.

cindylou7 Apprentice
cindylou7
Posted
  • Author

Yes, low IgA antibodies can affect blood tests & skin biopsies. But the question is moot b/c you have been gluten free for quite some time now. Cindylou, nothing you do short of eating gluten for some time will give you any positive test results now ---- NOTHING.

DH can break out at any time EVEN though you have been eating gluten free for up to 2 years & EVEN longer --- some texts say up to 10 years.

Thanks...

I wasn't wondering so I could test again, I had an "ah ha" moment and was looking for clarification. My IgA test results were in the low normal range and my tests have all been negative but I know I react to gluten and have improved bloodwork as a result of gluten-free diet.

I'm not certain that the cyst type acne is DH but I suspect it is. I have scarring from previous bumps and they don't have any pigmentation. The other blister type (herpes looking) bumps are easy to identify as different from other skin problems, but these are similar to acne. I thought it was unusual and suspect that they all popped out at once. Of course I looked for a cause...

squirmingitch Veteran
squirmingitch
Posted

We can have other skin problems in conjunction with the dh which can make figuring things out tricky. And from my own personal experience as well as what has been related on here by others as well as medical texts--- the darn dh can take so many forms. I had blisters, blisters, blisters & the bite kind of dh ---- now I'm in a spell where I'm not getting any blisters but the bite kind are prevalent as well as some that seem deep under the skin & they appear as red, inflamed bumps & they still itch like crazy but also sting & burn & they get really deep down sore --- hurts to touch them the least bit. I almost get bruising from them very faintly.

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    • knitty kitty
      My only proof

      By knitty kitty · Posted

      You're right, doctors usually only test Vitamin D and B12.  Both are really important, but they're not good indicators of deficiencies in the other B vitamins.  Our bodies are able to store Vitamin B12 and Vitamin D in the liver for up to a year or longer.  The other B vitamins can only be stored for much shorter periods of time.  Pyridoxine B 6 can be stored for several months, but the others only a month or two at the longest.  Thiamine stores can be depleted in as little as three days.  There's no correlation between B12 levels and the other B vitamins' levels.  Blood tests can't measure the amount of vitamins stored inside cells where they are used.  There's disagreement as to what optimal vitamin levels are.  The Recommended Daily Allowance is based on the minimum daily amount needed to prevent disease set back in the forties when people ate a totally different diet and gruesome experiments were done on people.  Folate  requirements had to be updated in the nineties after spina bifida increased and synthetic folic acid was mandated to be added to grain products.  Vitamin D requirements have been updated only in the past few years.   Doctors aren't required to take as many hours of nutritional education as in the past.  They're educated in learning institutions funded by pharmaceutical corporations.  Natural substances like vitamins can't be patented, so there's more money to be made prescribing pharmaceuticals than vitamins.   Also, look into the Autoimmune Protocol Diet, developed by Dr. Sarah Ballantyne, a Celiac herself.  Her book The Paleo Approach has been most helpful to me.  You're very welcome.  I'm glad I can help you around some stumbling blocks while on this journey.    Keep me posted on your progress!  Best wishes! P.S.  interesting reading: Thiamine, gastrointestinal beriberi and acetylcholine signaling https://pmc.ncbi.nlm.nih.gov/articles/PMC12014454/
    • NanceK
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    • knitty kitty
      Has anyone had terrible TMJ/ Jaw Pain from undiagnosed Celiac?

      By knitty kitty · Posted

      Segments of the protein Casein are the same as segments of the protein strands of gluten, the 33-mer segment.   The cow's body builds that Casein protein.  It doesn't come from wheat.   Casein can trigger the same reaction as being exposed to gluten in some people.   This is not a dairy allergy (IGE mediated response).  It is not lactose intolerance.  
    • trents
      Has anyone had terrible TMJ/ Jaw Pain from undiagnosed Celiac?

      By trents · Posted

      Wheatwacked, what exactly did you intend when you stated that wheat is incorporated into the milk of cows fed wheat? Obviously, the gluten would be broken down by digestion and is too large a molecule anyway to cross the intestinal membrane and get into the bloodstream of the cow. What is it from the wheat that you are saying becomes incorporated into the milk protein?
    • Scott Adams
      Has anyone had terrible TMJ/ Jaw Pain from undiagnosed Celiac?

      By Scott Adams · Posted

      Wheat in cow feed would not equal gluten in the milk, @Wheatwacked, please back up extraordinary claims like this with some scientific backing, as I've never heard that cow's milk could contain gluten due to what the cow eats.
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