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If Your Body Is Making Anti-Gliadin Antibodies, Doesn't That Mean You're Gluten Sensitive?

Seeking2012

By Seeking2012
in Related Issues & Disorders

Recommended Posts

gatita Enthusiast
gatita
Posted

Hi Gatita,

You may want to check with your lab to see what they mean by anti-gliadin antibodies....my recent labs were done through LabCorp through my M.D.s office and the results which were reported as anti-gliadin antibodies were actually DGP antibodies (as if things weren't confusing enough at baseline). So, perhaps you did actually have the right tests done.

Alas, no, it was not DGP...

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GottaSki Mentor
GottaSki
Posted

Not to worry - I cannot recall your serology - but I think you have improved gluten-free? Blood data is good to have - yet is not the end of the equation.

Hang in - it does get better :)

dilettantesteph Collaborator
dilettantesteph
Posted

My own theory is that celiac disease is just one form of gluten intolerance :D

Mine too.

plumbago Experienced
plumbago
Posted

Mine too.

Then what are the other forms of celiac disease? And, what is celiac disease?

Plumbago

GottaSki Mentor
GottaSki
Posted

Then what are the other forms of celiac disease? And, what is celiac disease?

Plumbago

I think Mushroom means there are many forms of Gluten Intolerance -- one being Celiac Disease and I agree.

  • 8 months later...
Seeking2012 Contributor
Seeking2012
Posted
  • Author

I'm posting this because my understanding on the topic has evolved and I wanted to post an update. I've been thinking about autoimmunity for some time. I've had this question floating around in my head: "If you're body makes any autoantibodies at all, doesn't that mean there is an antigen somewhere in your diet or environment that you need to be avoiding? Doesn't it mean that your immune response is confused? Is it true that the body should not make any autoantibodies at all? Is there any reason why the body should need to make them?"

 

The answer to this seems intuitive. Autoantibodies are antibodies that kill off your own body's cells. Well, someone somewhere (I thought it was this thread but I guess I was wrong) made a statement. He/she said: "I think that autoantibodoes are part of the body cleaning out dead cells."

That made some sense to me for a while, until I looked further into it today. It turns out that the "cleaning out of dead cells" in the body is called apoptosis and is done by phagoycites. I read this on wikipedia: "The removal of dying cells by phagocytes occurs in an orderly manner without eliciting an inflammatory response."

 

So this means that the body's immune response is not activated or involved in "cleaning out the body's dead cells (housecleaning)." This implies that autoantibodies are not produced for the purpose of housecleaning.

 

Is there any reason that the body would need to produce autoantibodies? Or does any (no matter how small) amount of production of autoantibodies mean that the immune system is confused?

 

And is there a way to "fix" the confused immune system so that it can once again tell the difference between self cells and non-self cells?

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    • knitty kitty
      Son's legs shaking

      By knitty kitty · Posted

      Blood tests for thiamine are unreliable.  The nutrients from your food get absorbed into the bloodstream and travel around the body.  So, a steak dinner can falsely raise thiamine blood levels in the following days.  Besides, thiamine is utilized inside cells where stores of thiamine are impossible to measure. A better test to ask for is the Erythrocyte Transketolace Activity test.  But even that test has been questioned as to accuracy.  It is expensive and takes time to do.   Because of the discrepancies with thiamine tests and urgency with correcting thiamine deficiency, the World Health Organization recommends giving thiamine for several weeks and looking for health improvement.  Thiamine is water soluble, safe and nontoxic even in high doses.   Many doctors are not given sufficient education in nutrition and deficiency symptoms, and may not be familiar with how often they occur in Celiac disease.  B12 and Vitamin D can be stored for as long as a year in the liver, so not having deficiencies in these two vitamins is not a good indicator of the status of the other seven water soluble B vitamins.  It is possible to have deficiency symptoms BEFORE there's changes in the blood levels.   Ask your doctor about Benfotiamine, a form of thiamine that is better absorbed than Thiamine Mononitrate.  Thiamine Mononitrate is used in many vitamins because it is shelf-stable, a form of thiamine that won't break down sitting around on a store shelf.  This form is difficult for the body to turn into a usable form.  Only thirty percent is absorbed in the intestine, and less is actually used.   Thiamine interacts with all of the other B vitamins, so they should all be supplemented together.  Magnesium is needed to make life sustaining enzymes with thiamine, so a magnesium supplement should be added if magnesium levels are low.   Thiamine is water soluble, safe and nontoxic even in high doses.  There's no harm in trying.
    • lizzie42
      Son's legs shaking

      By lizzie42 · Posted

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    • lizzie42
      Son's legs shaking

      By lizzie42 · Posted

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