- Celiac Disease Research: Associated Diseases and Disorders
- Diabetes and Celiac Disease
- Wheat Protein-fed Mice Show Higher Incidence of Diabetes and Intestinal Damage Than Those on Gluten-Free Diet
- Safe Gluten-Free Food List (Safe Ingredients)
- Unsafe Gluten-Free Food List (Unsafe Ingredients)
- Gluten-Free Alcoholic Beverages
- Celiac Disease Symptoms
- The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free
- Interpretation of Celiac Disease Blood Test Results
- Is Buckwheat Flour Really Gluten-Free?
Wheat Protein-fed Mice Show Higher Incidence of Diabetes and Intestinal Damage Than Those on Gluten-Free Diet
In 1994 I was diagnosed with celiac disease, which led me to create Celiac.com in 1995. I created this site for a single purpose: To help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives. Celiac.com was the first site on the Internet dedicated solely to celiac disease. In 1998 I foundedÂ The Gluten-Free Mall, Your Special Diet Superstore!, and I am the co-author of the book Cereal Killers, and founder and publisher of Journal of Gluten Sensitivity.View all articles by Scott Adams
Diabetologia. 2005 Apr 14
Celiac.com 04/29/2005 – According to Italian researchers an improper immune response to wheat may play an important role in the pathogenesis of Type 1 diabetes. The researchers fed one group of female non-obese diabetic (NOD) mice a standard gluten-free diet, while another group of NOD mice was fed a standard gluten-free diet that also included wheat proteins. The researchers then evaluated the small intestinal architecture of the mice and found that the wheat-protein group "showed reduced villous height, increased intraepithelial infiltration by CD3(+) cells and enhanced expression of H2-IA and IFN-gamma mRNA when compared with mice on the gluten-free diet." After 43 weeks the cumulative incidence of diabetes was 65% in the gluten-free group, and 97% in the wheat-protein group. The researchers conclude that the mice that ate wheat proteins had a much higher incidence of diabetes and small intestinal enteropathy that included higher mucosal levels of pro-inflammatory cytokines.
As always, Celiac.com welcomes your comments (see below).
- Patients with Celiac Disease Have Lower Rates of Non–Insulin-Dependent Diabetes Mellitus and Metabolic Syndrome
- Anti-infectious and Autoimmune-associated Autoantibodies in Patients with Type I Diabetes Mellitus and Celiac Disease
- Beta-Cell Autoimmunity Screens Unwarranted in Celiac Children
- Celiac Disease 20 Times More Likely for Those with Type 1 Diabetes