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Need Help With Blood Results


.byrdie

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.byrdie Newbie

I know that based on my results from my Celiac Blood Panel that I am negative for Celiac Disease, but I was curious if my results could mean that I am "gluten sensitive"...

 

Any help is appreciated

 

Results:

 

Tissue Transglutaminase AB, IGA - 1     <4 No anitobody detected

                                                                > or = 4 antibody detected

 

Immunoglobulin A - 306                            81 - 463 mg/dL

 

 

Gliadin (Deamidated) AB (IGA) - 7          <20 antibody not detected

                                                                 > or = 20 antibody detected

 

 

I have a lot of the symptoms for gluten sensitivity, such as: bloating, gas, fatigue, joint pain, getting full quickly, irritable, anxiety, loose stools, migraines, ear infections, etc...

 

Thanks in advanced to whomever answers :)


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nvsmom Community Regular

Your symptoms would certainly point to non-celiac gluten intolerance (NCGI) - those gluten migraines are killers! Celiac blood tests do not indicate NCGI if they are low. Celiac blood tests are largely in response to the damage being done to the intestines, and NCGI patients do not have dmagae to the intestines (although they appear to have every other horrible symptom). Your tests are negative, so I would guess you don't have celiac; you could always request the EMA IgA, DGP iGG, AGA IgG and AGA IgA, and tTG iGG for further blood testing, or even the biopsy if you really think it's celiac (based on family history or other info).

 

If you can't do further testing, I would advise you to go gluten-free for at least 4-6 months. You have some pretty classic symptoms that will probably disappear over time on the gluten-free diet.

 

Good luck!

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      Thanks for the reply. 
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      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
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