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Gluten-free Diet Helpful in Reducing Gastroesophageal Reflux Disease-related Symptoms

Celiac.com 11/21/2008 - Not much is known about what effects, if any, a gluten-free diet might have upon gastroesophageal reflux disease-related symptoms (GERD-rs) in people with celiac disease. A team of researchers recently set out to assess the recurrence of GERD-rs, in celiac patients with nonerosive reflux disease (NERD).

Out of a total of 105 adult patients with celiac disease, the team found 29 with celiac disease who presented with the NERD. Those 29 were enrolled in the study, and compared against a control group of thirty non-celiac patients with NERD.

After 8 weeks of PPI treatment the team found that 25 (86.2%) celiac patients saw GERD-rs resolve, compared to just 20 (66.7%) control subjects. The team used clinical means to assess recurrence of GERD-rs at 6, 12, 18, and 24-month intervals after initial proton-pump inhibitor (PPI) treatment were withdrawn for 8 weeks.

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In the celiac disease group, just five patients (20%) had a recurrence of GERD-rs at 6 months, but none had recurrence at 12, 18, and 24 months, while the control group showed recurrence in six of 20 controls (30%) at 6 months, in another six (12/20, 60%) at 12 months, in another three (15/20, 75%) at 18 months, and in another two (17/20, 85%) at 24 months.

This is the first study to evaluate the effect of a gluten free diet in the nonerosive form of GERD in patients with celiac disease, via a clinical long-term follow-up, and the results suggest that a gluten free diet could be helpful reducing GERD symptoms and in preventing of their recurrence.

J Gastroenterol Hepatol.  2008;23(9):1368-1372.

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5 Responses:

 
Anne
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said this on
22 Nov 2008 5:56:20 AM PDT
I would like to see a study where they people with GERD but no celiac disease on a gluten free diet. Even though they don't have celiac disease, I bet a large number of these people would have resolution in symptoms.

I do not have biopsy proven celiac disease and all my GERD disappeared 5 years ago with the start of a gluten free life. I was able to throw away my acid blockers and remove the blocks elevating the head of my bed.

 
Jan
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said this on
02 Dec 2008 10:02:39 AM PDT
I found this very interesting. My son was diagnosed with gluten-intolerance, and like Anne, we did not have him biopsied, just began the diet. We decided to make our household gluten-free, and the only time I ever have 'heartburn' is when I go out and eat gluten!

 
michelle
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said this on
08 Dec 2008 8:20:17 PM PDT
I am very confused. I am still new to this disease, but it is my understanding that to control it you must have a gluten free diet to begin with. How can they test the effects of a gluten free diet on people with celiac, when to control their disease they have to be gluten free? Am I reading this wrong? Also Anne they did test the gluten free diet on non celiac patients? They were the control group. 20 out of 29 were helped.

 
Jami R.
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said this on
15 Dec 2008 2:08:04 PM PDT
I found that eating mostly regular-gluten free table foods (meat veggies, fruits) helps relieve me of my GERD, but not completely. A Gastro Physician prescribed a prescription pill from my gut.

 
mike
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said this on
10 Oct 2011 2:06:49 PM PDT
I have had GERD for years and recently became intolerant of ppi's. I might have to try the gluten thing as I am definitely struggling right now.




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