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Test Results Back


sharese28

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sharese28 Apprentice

I went to the gastro today and got my test results back iga Total Serum 369.61 Tissue Transglutaminase TTG IgG 39 my biopsy was negative but he told me that he's confident it's celiac go on  the gluten free diet for three months and see how i feel they will test me again in three months to check for antibodies feedback please on my test results :D  :D  :D


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mushroom Proficient

You don't give the ranges on your results but I'm assuming that everything over 30 on your tTG IgG was a positive, and I'm assuming that your IgA total serum fell within the normal range.  Doctors prefer to have the IgA result be positive if you make normal quantities of IgA, but you can certainly be celiac with a high IgG too.  It sounds like your doctor is willing to diagnose you as celiac positive even though the biopsy was negative, if you improve on the diet and your tTG IgG score goes down.

 

I hope this is an accurate result and that you start feeling better soon. :)

sharese28 Apprentice

yes my iga total serum was within normal range can you be gluten sensitive with a high ttg igg

mushroom Proficient

You can read up a bit here about the meanings of test results:

 

MEANINGS OF TESTS
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beachbirdie Contributor

It's not as common to be diagnosed with celiac if only the Ttg IgG is positive.  Especially with negative biopsy.  Your doc is good to have you go gluten free anyway.

 

Did you get a copy of your biopsy report?  Do you know how many samples they took?  If they took only a small sampling, they might have missed damage.

 

Also, did your doc make sure to rule out other conditions that might also raise the IgG...like Crohn's disease and other autoimmune conditions.

 

Just to be sure.  Hopefully the diet will help and you'll be on your way to feeling great!

GottaSki Mentor

I think it very wise to remove all gluten at this point -- three months is good - six is better to monitor for symptom improvement and re-test -- the tTG IgG should go down once gluten has been removed -- this can take time.  All of my celiac antibodies were reduced at three months, but weren't at their lowest levels until six months gluten-free.  

 

Here is hoping you will know quickly if gluten is the problem -- good luck with the transition -- it can be tough....reading as much as you can and asking questions really does speed up the process.

 

Good Luck to you :)

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      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
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      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
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