Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Son's Prometheus Test Results

bayba792

Recommended Posts

bayba792 Rookie
bayba792
Posted

I have posted on here several times and you all have been so kind and patient with me. I just received my son's Prometheus test results and would like some clarification.

 

This is my son's test results:

 

DGP IgG 0.4 EU/ml - <4.9 EU/ml

DGP IgA 1.7 EU/ml - <6.1 EU/ml

TTG IgA 0.6 U/ml - <10.3 U/ml

EMA IgA NEGATIVE - NEGATIVE

TOTAL IgA 209 mg/dl   41-395 mg/dl

 

CELIAC RISK HAPLOTYPE DETECTED:

 

DQ2.2 (HLA DQA1*0201:DQB1*0202) AND DQ8 (HLA DQA1*03:DQB1*0302)

 

CATEGORY #       DQ GENOTYPE     INCREASED RISK    RELATIVE RISK

        6                      DQ2/DQ8                    14X                      VERY HIGH

 

My son has been gluten-free for 5 months before this test was done so the Dr said that she would expect the serological markers to be negative.

 

This was my husband's results to the same test:

 

Deamidated Gliadin Peptide Antibody,
IgG (DGP IgG) 9.2 EU/ml + <4.9 EU/ml
Deamidated Gliadin Peptide Antibody,
IgA (DGP IgA) 15.0 EU/ml + <6.1 EU/ml
Anti-Human Tissue
Transglutaminase IgA (TTG IgA) 2.3 U/ml - <10.3 U/ml
Anti-Endomysial IgA IFA (EMA IgA) Negative Negative
Total Serum IgA
By Nephelometry (TOTAL IgA) 308 mg/dl <3 Yrs: 8-220 mg/dl
3-13 Yrs: 41-395 mg/dl
>13 Yrs to adult: 44-441 mg/dl
Celiac Risk Haplotype: DQ8(HLADQA1*03:DQB1*0302)AND OTHER NON-RISK
ALLELES.
Category # DQ Genotype Increased Risk Over General Population Relative Risk
------------------------------------------------------------------------------
3 DQ8 HETEROZYGOUS 2X MODERATE
------------------------------------------------------------------------------
 
sorry so long but from what I understand is that I carry DQ2 and that is why my son has both? Do I need to be tested and also my 5 year old son? We have no GI problems when we eat gluten but we are completely gluten-free in the house and I do not cheat because I have noticed improvements other than GI clear up on gluten-free diet but I notice that if my youngest son eats gluten at school (cupcakes when it's someone's birthday) he gets a rash on his butt cheeks and under his testicles, could this be related?
 
Thank you!!!!
<3 <3 <3
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Lock Newbie
Lock
Posted

Whether you get yourself and your son tested is up to whether you want to spend the money and go through the trouble but yes, the gluten sensitive/celiac genes are in your family and it is probably good for all of you that you are gluten free. For your 5 year old, from my perspective with my children now in their twenties, I no longer have any control over their health. Looking back, if they had had the gene tests back when they were little I would have got them so that they would maybe take being gluten free more seriously.

 

From my interpretation of the test results, which I am an amateur by the way, it does seem you have the DQ2 gene and your husband has the DQ8 but heterogenous which means he also has a non-gluten gene. IF you also have one gluten gene and one non gluten gene then your 5 year old has a 1/4 chance of having NO gluten genes, if that makes sense. But that also means he has a 75% chance of having at least one. So if you don't get him gene tested, it would be good to watch him for symptoms. Also, living in a gluten free home could potentially protect him from getting sick later. However, you will rapidly lose control as he grows, goes to school, etc.

 

I don't think it would be worth it to go on gluten to try to tease out a diagnosis, but in my opinion, getting the test and having the information to give your child is a good idea. Then as he becomes an adult and has to make his own food choices he will at least know if he is at risk of celiac disease or gluten related problems.

w8in4dave Community Regular
w8in4dave
Posted

I agree with Lock. I think having them tested does make for better choices in the future. 

nvsmom Community Regular
nvsmom
Posted

Yes, you and your 5 year old should be tested, your son especially and his test should be repeated every few years if it is negative.

I hope your husband is going gluten-free after those positive tests.

bayba792 Rookie
bayba792
Posted
  • Author

Thank you so much for responding. I will get my 5 year old son tested, I was under the impression that he would have both like my oldest so it would be good to find out. I called my son's doctor and made an appointment for the testing.

 

nvsmom, my husband was gluten free for 3 months before this test so the GI specialist is keeping a close eye on him because of his numbers. He wants to see my husband in 3 months to see if his numbers come down more. He is feeling excellent now that he is gluten free. 

nvsmom Community Regular
nvsmom
Posted

Glad he is feeling good. It takes a while for those numbers to come down, doesn't it?

Good luck with all the testing. :)

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. Mari
      - Mari replied to KathyR37's topic in Coping with Celiac Disease
      5

      New here

      Hi Katht - I sympathize with your struggles in following a gluten-free diet and lifestyle. I found out that I had Celiac Disease a few months before I turned 70. I just turned 89 and it has taken me almost 20 years to attain a fairly normal intestinal function. I also lost a lot of weight, down to 100 lb. down from about 140 lb. What Trents wrote you was...
    2. Colleen H
      - Colleen H replied to Colleen H's topic in Gluten-Free Foods, Products, Shopping & Medications
      15

      Ibuprofen

      Yes thyroid was tested.. negative Iron ...I'm. Not sure ... Would that fall under red blood count? If so I was ok Thank you for the detailed response..☺️
    3. Colleen H
      - Colleen H posted a topic in Coping with Celiac Disease
      0

      Methylprednisone treatment for inflammation?

      Hi all !! Did anyone ever get prescribed methylprednisone steroids for inflammation of stomach and intestines? Did it work ?? Thank you !!
    4. cristiana
      - cristiana replied to Colleen H's topic in Gluten-Free Foods, Products, Shopping & Medications
      15

      Ibuprofen

      Hi Colleen Are you supplementing B12/having injections? I have learned recently that sometimes when you start addressing a B12 deficiency, it can temporarily make your symptoms worse. But it is important not to stop the treatment. Regarding your problems with anxiety, again that is another symptom of a B12 deficiency. I didn't know...
    5. Jmartes71
      - Jmartes71 posted a topic in Coping with Celiac Disease
      0

      My only proof

      Hello still dancing around my celiac disease and not getting medically backed up considering Ive been glutenfree since 1994.All my ailments are the core issue of my ghost disease aka celiac disease. Im angery because the "celiac specialist " basically lightly dismissed me.Im extremely angery and fighting for a new primary care physician which is hard to do...
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,877
    • Most Online (within 30 mins)
      7,748
    Christian Konig
    Newest Member
    Christian Konig
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Mari
      New here

      By Mari · Posted

      Hi Katht -  I sympathize with your struggles in following a gluten-free diet and lifestyle. I found out that I had Celiac Disease a few months before I turned 70. I just turned 89 and it has taken me almost 20 years to attain a fairly normal intestinal  function. I also lost a lot of weight, down to 100 lb. down from about 140 lb. What Trents wrote you was very true for me. I am still elimination foods from my diet. One person suggested you keep a food diary and that is a good idea but it is probably best just to do an elimination diet. There are several ne and maybe one for celiacs. I used one for a while and started with plain rice and zucchini and then added back other foods to see if I reacted or not. That helped a great deal but what I did not realise that it would only very small amounts of some foods to cause inflammation in my intestine. Within the last few years I have stopped eating any trace amounts of hot peppers, corn and soy(mostly in supplements) and nuts, (the corn in Tylenol was giving me stomach aches and the nuts were causing foot pains). Starting an elimination diet with white rice is better than brown rice that has some natural toxins. In addition it is very important to drink sufficient plain water. You can find out how much to drink for your height and weight online. I do have difficulty drinking 48 ounces of water but just recently have found an electrolyte supplement that helps me stay well hydrated, Adding the water and electrolytes may reduce muscle cramps and gag spams you wrote about. . Also buy some anti-gluten enzyme capsules to take with meals. I use GliadinX advertised here. These are a lot of things to do at one time as they reflect my 20 years of experience. I hope you do what you can manage to do over time. Good luck and take care.
    • Colleen H
      Ibuprofen

      By Colleen H · Posted

      Yes thyroid was tested.. negative  Iron ...I'm. Not sure ... Would that fall under red blood count?  If so I was ok  Thank you for the detailed response..☺️
    • Colleen H
      Methylprednisone treatment for inflammation?

      By Colleen H · Posted

      Hi all !! Did anyone ever get prescribed methylprednisone steroids for inflammation of stomach and intestines?  Did it work ??  Thank you !! 
    • cristiana
      Ibuprofen

      By cristiana · Posted

      Hi Colleen Are you supplementing B12/having injections? I have learned recently that sometimes when you start addressing a B12 deficiency, it can temporarily make your symptoms worse.  But it is important not to stop the treatment.  Regarding your problems with anxiety, again that is another symptom of a B12 deficiency.   I didn't know what anxiety was until it hit me like a train several months before gastrointestinal issues began, so I can certainly relate.   Two books which helped me hugely were At Last A Life by Paul David (there is a website you can look up) and The Depression Cure: The Six-Step Programme to Beat Depression Without Drugs by Dr Steve Llardi.  Although his book is aimed at people who have depression, following the principals he sets out was so helpful in lessening my anxiety.  Llardi suggests we need to focus on getting enough: - physical exercise - omega-3 fatty acids - natural sunlight exposure - restorative sleep - social connectedness - meaningful, engaging activity   ... and we should feel a lot better. That is not to stay you must stop taking medication for depression or anxiety if you have been prescribed it, but adopting the changes Dr Llardi sets out in the book should really help. Can I just ask two more questions:  1) you say that you are B12 deficient, did they test your iron levels too?  If not, you really ought to be checked for deficiency and, 2) did they check your thyroid function, as an overactive thyroid can be cause rapid heartbeat and a lot of coeliacs have thyroid issues? Cristiana        
    • Jmartes71
      My only proof

      By Jmartes71 · Posted

      Hello still dancing around my celiac disease and not getting medically backed up considering Ive been glutenfree since 1994.All my ailments are the core issue of my ghost disease aka celiac disease. Im angery because the "celiac specialist " basically lightly dismissed me.Im extremely angery and fighting for a new primary care physician which is hard to do in Northern Cali.So currently without and looking.Im angery that its lightly taken when its extremely serious to the one who has it.My only evidence is a brochure back in the days when I got news letters when I lived at my parents.It was published in 1998.I was diagnosed before any foods eliminated from my diet. Angery doctors don't take seriously when Im clearly speaking.I did write to the medicine of congress and have case number.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.