Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Treating Celiac With Psychedelic Drugs?


poneelovesyou

Recommended Posts

poneelovesyou Newbie

So, I know what youre thinking, madness! BUT, after reading this paper recently, I started  to think a bit.

 

Open Original Shared Link

 

So recently I realized that gluten was the cause of my lifelong struggle with depression and anxiety. I also have some evidence that I may be a celiac, but I am not willing to do the gluten challenge in order to find out. Regardless of it I am or not, there are 2 things that have erradicated chemical depression and anxiety from my life: Psychedelic drugs and a gluten-free diet. So the paper above is really interesting because it talks about a psychedelic (DOI) that primarily operates through the 5HT2a receptor (as do the classical psychedelic drugs such as LSD, psilocybin, DMT, mescaline etc). So they observed that through this receptor acitivity specifically, anti-inflammatory effects were observed in specific tissues in the body. One of these areas was the small intestine.

 

Still following me? So, in theory, other 5HT2a agonist may also facilitate this same anti inflammatory effect in the small intestine. obviosuly inflammation of the gut is one of the things that plagues celiacs and NCGS people, so I'm wondering if perhaps psychedelics and a gluten-free diet were treating my depression through the same mechanism; reducing inflammation in the small intestine (and perhaps other areas in the gut?)

 

So now I'm wondering, could psychedelic drugs be a potential candidate to reduce the gut inflammation in celiac disease patients? It seems like these cascading inflammatory processis are what takes so long for the body to get under control even after removing gluten from the diet, and continue to do damage to the body. What do you guys think?


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



ravenwoodglass Mentor

The only way something like that would be feasible is if they were able to remove the psychedelic aspect of the drug. I don't think the general population would get much done during the day while they were watching the walls turn colors and their grasp on the reality around them was oozing away. Psychedelic drugs can also be dangerous for people with certain mental health issues. 

mommida Enthusiast

There would have to be many more years of research before I would trust be treated with psychedelic drug treatment.  I have seen LSD proposed as possible treatment for other disorders an health conditions.

 

I hope you are taking extreme precautions, because I do not believe you are under a doctor's care for your experimentations.  I have seen people completely "bake" their brains on drugs to the point they need to be kept in an institution.  Look at Ozzy Osbourne, he can't really speak anymore, but his family is wealthy enough to have servants care for some of the extreme behavior.  Don't forget his wife admits to a few times he has tried to kill her.

 

There has been research in a home, were a gluten free diet improved some mental disorders and most here have experienced a withdrawal period removing gluten from the diet.   

 

You might wan to look further into the "gut - brain connection theories"  or first brain? gut/mind

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      131,776
    • Most Online (within 30 mins)
      7,748

    peskywabbit
    Newest Member
    peskywabbit
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Scott Adams
      The following two lists are very helpful for anyone who is gluten sensitive and needs to avoid gluten when shopping. It's very important to learn to read labels and understand sources of hidden gluten, and to know some general information about product labelling--for example in the USA if wheat is a possible allergen it must be declared on a product's ingredient label like this: Allergens: Wheat.      
    • trents
      Tammy, in the food industry, "gluten free" doesn't mean the same thing as "no gluten". As Scott explained, the FDA (Food and Drug Administration) allows food companies to use the "gluten-free" label as long as the product does not contain more than 20 ppm (parts per million) of gluten. This number is based on studies the FDA did years ago to determine the reaction threshold for those with celiac disease. And the 20 ppm figure works for the majority of celiacs. There are those who are more sensitive, however, who still react to that amount. There is another, stricter standard known as "Certified Gluten Free" which was developed by a third party organization known as GFCO which requires not more than 10 ppm of gluten. So, when you see "GFCO" or "Certified Gluten Free" labels on food items you know they are manufactured with a stricter standard concerning gluten content. Having said all that, even though you may read the disclaimer on a food item that says the spices may contain wheat, barley or rye (the gluten grains), you should be able to trust that the amount of gluten the spices may contain is so small it allows the total product to meet the requirements of gluten free or certified gluten free labeling. I hope this helps.
    • Tammy Pedler
      As soon as I see gluten free I read the labels. I always find stuff that I cannot have on the products them selfs. Like spices, when the labels says  everything listed and then after like say garlic salt then the next thing is spices. When it says that that can contain wheat and other things I can’t have.. 
    • Scott Adams
      While hypoglycemia isn't a direct, classic symptom of celiac disease, it's something that some individuals with well-managed celiac disease report, and there may be a few plausible explanations for why the two could be connected. The most common theory involves continued damage to the gut lining or nutrient deficiencies (like chromium or magnesium) that can impair the body's ability to regulate blood sugar effectively, even after gluten is removed. Another possibility is delayed stomach emptying (gastroparesis) or issues with the hormones that manage blood sugar release, like glucagon. Since your doctors are puzzled, it may be worth discussing these specific mechanisms with a gastroenterologist or endocrinologist. You are certainly not alone in experiencing this puzzling complication, and it highlights how celiac disease can have long-term metabolic effects beyond the digestive tract.
    • trents
      Paracetamol, aka, acetaminophen (Tylenol) just does not do anything for me as far as pain relief. It does help with fevers, though.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.