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Half Dq2 And Celiacs ?

whitefairy30

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whitefairy30 Rookie
whitefairy30
Posted

Hi all.

 

Just want to know if there are anyone who just diagnosed with HLA DQB1*0201, without DQA1*0501 and celiacs. 

 

Thanks. 

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LauraTX Rising Star
LauraTX
Posted

Yes, you can have one copy of the DQ2 gene (referred to as heterozygous) and get Celiac disease.  That gene is not one where you have to have two copies for it to present itself, so having one means Celiac can be a possibility.  Of course, having the gene alone does not mean you have Celiac disease, you do need to get other testing done to see if Celiac disease is active.

whitefairy30 Rookie
whitefairy30
Posted
  • Author

Yes I know that. 

I'd just curious if there are person with this genetic type and get celiacs :)

LauraTX Rising Star
LauraTX
Posted

Yes, there are people with this genetic type that have celiac disease.  Go to the main page of the forum and search "one copy of dq2" and there will be many threads to read through that may give you the information you need.

whitefairy30 Rookie
whitefairy30
Posted
  • Author

Thanks. :)

whitefairy30 Rookie
whitefairy30
Posted
  • Author

I read a lot but I have some questions:

 

My lab report only this: 

 

DQA1*0501: negative

DQB1*0201: positive

DQB1*0302: negative

 

Here I read in so many post speak about DQ1, DQ3, DQ4, DQ5, DQ6, etc. 

 

I think my lab tested only this 3 combination for research of celiacs predisposition (DQ2 / DQ8).

 

I'd like to go in another laboratory and done other more accurate analysis. 

 

Maybe I have other positive gene and I don't know.

 

I don't know what gene I should test, what do you think ? 

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