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Genetic Test

KenzMom

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KenzMom Rookie
KenzMom
Posted

Does anyone know the likelihood of a young child (almost 2) developing celiac (or possibly already have it but undiagnosed) if they have been diagnosed with gluten intolerance and carry DQ2 and DQ8?

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Judy3 Contributor
Judy3
Posted

Just my opinion but if the child has the genes AND has gluten intolerance already that is Celiac.

nvsmom Community Regular
nvsmom
Posted

30% of everyone on Earth has the DQ2 and / or the DQ8 genes but less than 1 % of the world has celiac disease.  Of that <1%, 97% of the celiacs have the DQ2 or DQ8 genes.  If my math is approximately right, that means that about 2-3% of that 30% will have celiac disease.  Chances are low, statistically speaking.

 

As a mom of children who have a gluten sensitivity, and a mother who has celiac disease, I'm assuming they have celiac disease and have made them gluten-free.  I found the option of continuing to feed them gluten, until one day they may get sick enough to give a positive test result, completely unacceptable.  Feeding us is inconvenient, but they are healthy.

 

She could have celiac disease but there is no way to know for sure unless she continues to eat gluten and you keep retesting.  :(  I wish there was a better way to test.

ravenwoodglass Mentor
ravenwoodglass
Posted

If she has been diagnosed with 'gluten intolerance' and has both the most commonly associated celiac genes she likely has celiac,IMHO. Testing on little ones is not very reliable, from what I understand, and she may have had a false negative. What celiac testing did she have and what were those results?

KenzMom Rookie
KenzMom
Posted
  • Author

She was also diagnosed with milk protein allergy-- although I've wondered if it was a true allergy...

Anyways, her biopsies were negative. Her bloodwork was very negative. They tested gliadin IGG & IGA, TTG IGA & IGG. And her IGA was at the bottom of the range. She was 21, range was 20-100.

I am a type 1 diabetic and do not have celiac disease. Her father does not have celiac disease but he has a distant cousin with celiac.

nvsmom Community Regular
nvsmom
Posted

I would declare her a celiac and live gluten-free too.

 

You and her dad should be tested every couple of years too.

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