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Celiac and Levaquin or PFC Chemicals


RVLori

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RVLori Rookie

I was diagnosed with Celiac 6 years ago, microscopic colitis 11 years ago.  In April 2016 I had my appendix out.  I was put on Levaquin and another antibiotic.  About a week later my bowel symptoms improved so much, I thought I found the cure, have your appendix out.  About 5 weeks later things went down fast.  I have had severe diarrhea since.  Finally went to the gastro in December.  Yes, he asked more then once how long I had the diarrhea for, but prior to being diagnosed Celiac I had it for years, so I didn't think much about it.  He first put be on Budesonide EC 3 MC Cap treatment from December until sometime in April when I  started weaning off of it.  My symptoms then returned as bad, if not worse then before starting treatment.  So back to gastro.  I asked to be put back on the Budesonide, and in passing told him I just found out I had been exposed to PFC Chemicals in Oscoda Michigan, not thinking much about it.  He put me on Apriso (mesalamine).  I wasn't thrilled, because I knew the Budesonide worked.  He said you should not be on it for more than a year.  I had 8 more months before hitting a years, but the samples were free and the other stuff is expensive.  When I got home I looked up Apriso.  It is used to treat Ulcerative Colitis.  I've never been diagnosed with that.  More research on PFC Chemicals, and it is linked to causing Ulcerative Colitis.  So the Levaquin threw me into a tailspin, and now I may be finding out I have more problems from PFC Chemicals than one would hope.  It is just starting to hit the news that the stuff is everywhere, and in some places in very high concentrations.  Good luck to all.


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    • MogwaiStripe
      I had to rush to the hospital last week due to anaphylactic shock from taking a dose of an antibiotic. Received EpiPen, steroids, antihistamines, zofran (all injected/IV). When I woke up the next day, ALL of the rashes I've had that started since going gluten free were cleared up. EVEN THE dermatitis herpetiformis was gone. Has anyone else experienced this or happen to know why that would happen? The meds they gave me were all meds that I've taken to try to resolve the rashes, but they never worked in pill form. I'm wondering if it the addition of the epi that helped, it if injected steroids and antihistamines were what did the job.
    • Dr. Gunn
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    • trents
      What Dr. Gunn states is essentially true. It is a rule out measure. But be aware that to possess either of the two primary genes that have been identified with celiac disease (or both) doesn't necessarily mean that you have or will develop celiac disease. Almost 40% of the general population carries one or both but only about 1% of the general population will develop active celiac disease. It remains latent until triggered by some stress event which may or may not occur. So, there is a genetic component to celiac disease but there is also an epigenetic component. 
    • Dr. Gunn
      Have you had celiac genetic risk testing? A celiac genetic test is accurate with or without gluten in your diet. If you don't carry the celiac risk genes you can effectively rule out celiac disease for life. 
    • Scott Adams
      Based on those results alone, it’s not possible to say you have celiac disease. The test that is usually most specific for celiac, tTG-IgA, is negative in your results, and the endomysial antibody (EMA) is also negative, which generally argues against active celiac disease. However, your deamidated gliadin IgA is elevated, and your total IgA level is also high, which can sometimes affect how the other antibody tests behave. Another important factor is that you were reducing gluten before the test, which can lower antibody levels and make the results less reliable. Because of that, many doctors recommend a gluten challenge (eating gluten regularly for several weeks) before repeating blood tests or considering an endoscopy if symptoms and labs raise concern. It would be best to review these results with a gastroenterologist, who can interpret them in context and decide whether further testing is needed.
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