Please help me determine my results - Low IGA and IGG

[adm0707]

Hi there,

 

Can you please help me determine my results? I'm so confused by everything I see online. I don't believe I had my total IGA test done. Here is all I see:

Antigliadin Abs, IgA

Deamidated Gliadin Abs, IgA - Range (0-19 = Negative) (20-30 = Weak Positive) (>30 Moderate to Strong Positive)

Results= 4

Antigliadin Abs, IgG

Deamidated Gliadin Abs, IgG - Range (0-19 = Negative) (20-30 = Weak Positive) (>30 Moderate to Strong Positive)

Results= 4 

Reticulin IgA Antibodies

Results= Negative

t-Transglutaminase (tTG) IgA - Range (0-3= Negative) (4-10 Weak Positive) (>10 Positive)

Results= <2

[tessa25]

All 4 tests look to be negative. I'm not a doc.

[cyclinglady]

That Reticulin test is pretty darn old and has been long replaced with the TTG, DGP and EMA.  Are you outside of the US?  Your doctor should probably test you for an IgA deficiency.  So, you can not rule out celiac disease yet.  

Here is a government site discussing that Reticulin is obsolete:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623418/

Consider trying to find a doctor who is celiac savvy:

http://www.cureceliacdisease.org/screening/

[adm0707]

2 hours ago, cyclinglady said:

That Reticulin test is pretty darn old and has been long replaced with the TTG, DGP and EMA.  Are you outside of the US?  Your doctor should probably test you for an IgA deficiency.  So, you can not rule out celiac disease yet.  

Here is a government site discussing that Reticulin is obsolete:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623418/

Consider trying to find a doctor who is celiac savvy:

http://www.cureceliacdisease.org/screening/

Thank you! I’m in the US. Do the rest of the tests I was tested for matter though? I saw that since I was tested for IgG that it should be enough confirmation, even if I am IgA deficient. 

Only 2% of Celiacs are igA deficient, right?

Edited March 9, 2019 by adm0707

[cyclinglady]

You are correct, only about 2% are IgA deficient. However, some celiacs are seronegative (never get a positive on the celiac panel).    Your doctor may want to do an endoscopy despite your results or have you trial the gluten-free diet.  This is a conversation you need to have with him or her.

What made you get tested?  

 

[adm0707]

Thank you for confirming :). A lot of what I see online is confusing. Besides the Reticulin test, the others I tested for should relevant, right? Especially the igG one? 

My doctor didn’t push me to get tested for Celiac. I was diagnosed with eosinophillic esophagitis and have had lots of nausea and regurgitation, so I wanted to rule out Celiac. I also got tested for it with the Entero Labs stool test (do people still use those?) about ten years ago and the igA was in the normal levels. 

Thank you for listening, by the way.

[cyclinglady]

With 80% of celiacs undiagnosed, it was good that you requested celiac testing.  ?  The other tests were all valid.  

Have you changed your diet or determined triggers for your EoE?  

 

Edited March 9, 2019 by cyclinglady