Biopsy Results

[PixeI]

So I had a blood test and this is what I got:

Tissue Transglutaminase Immunoglobulin A (IgA): 25 U/mL

Abnormal <=14 ... though when I talked to the Dr he said it's supposed to be 1.  He then told me I had celiac disease.  I told him I can't have celiac disease.  He said he would do an endoscopy and colonoscopy.

He has been on vacation forEVER and it now just dawned on me that I have the results, I just don't know what they  mean.


In the OR notes, it says: "The second and third parts of the duodenum looked normal; however, the first part of the duodenum had some bumpiness to it that could reflect celiac disease."

And here is the surgical pathology notes.  I see 'patchy villous blunting', 'attenuated surface epithelium' and 'intraepithelial lymphocytosis, in keeping with lymphocytic colitis'

....So does this mean I have lymphocytic colitis instead of celiac disease?  There is a note of 'celiac?' in the Clinical History section but ... that's because they don't have my clinical history.  Do they not know?  I thought this was the gold standard of diagnosis?  I have been waiting for a month to get an answer back..... I can't wait any more..........

Please help if you can.


------------

 

DIAGNOSIS 1. Terminal ileum biopsy; Small bowel mucosa, no diagnostic abnormality.

2, 4, 5. Ascending, transverse, descending colon biopsies: Colonic mucosa, attenuated surface epithelium, intraepithelial lymphocytosis, in keeping with lymphocytic colitis.

3. Hepatic flexure polyp: Tubular adenoma, negative for high-grade dysplasia.

6. Rectum polyp: Tubulovillous adenoma, negative for high-grade dysplasia.

7,8. Duodenum 2,3 part biopsies: Duodenal mucosa, no diagnostic abnormality.

9. Duodenal cap biopsy: Duodenal mucosa, patchy villous blunting, no increase in intraepithelial lymphocytes, see comment.

10. Gastric antrum biopsy: Gastric antral mucosa, mild chronic gastritis, no activity, negative for H. pylori and intestinal metaplasia.

11. Gastric antrum ulcer biopsy: Antral type mucosa, reactive gastropathy with erosion, negative for H. pylori, intestinal metaplasia and dysplasia.

12. Gastric body biopsy: Gastric oxyntic mucosa, no significant abnormality, negative for H. pylori and intestinal metaplasia.

13. GE junction biopsy: Gastric cardia type mucosa, mild foveolar hyperplasia, negative for intestinal metaplasia and dysplasia.

CLINICAL HISTORY ? micro/collag colitis, ?adenomas ? celiac ? H Pylori ? ulcer ? reflux

[trents]

It seems clear to me, both from the antibody blood test and from the endoscopy, that you have celiac disease and you may also have colitis. There is a statistically higher incidence of IBS and colitis among the celiac population than is found outside the celiac population.

[Scott Adams]

I'm curious why you would say this to your doctor: "I told him I can't have celiac disease"? Both your test results that you've shared here, and your own doctor have indicated that you likely do have celiac disease.

[PixeI]

1 hour ago, Scott Adams said:

I'm curious why you would say this to your doctor: "I told him I can't have celiac disease"? Both your test results that you've shared here, and your own doctor have indicated that you likely do have celiac disease.

Hey, sorry!

The doctor caught me completely by surprise.  I was just going in for a colonoscopy to screen for cancer (it runs in my family) and I didn't know he did a ttg iga test at that point.  Just before I was about to get sedated for the colonoscopy (which didn't WORK, btw!  I was awake and lucid for the whole thing!) he goes 'Oh by the way, you have celiac disease."

I was taken aback and said "No I don't!  I can't have celiac!  All I eat is bread and pasta!"

He said "Well now we're also going to do an endoscopy to confirm.  Let's check to be sure."

Then he went on vacation for a month and a half.  So I've just been left with this partial information on my own and going bananas.  In the meantime I have continued to eat gluten.  I just want to know if I actually have it or not.

[PixeI]

2 hours ago, trents said:

It seems clear to me, both from the antibody blood test and from the endoscopy, that you have celiac disease and you may also have colitis. There is a statistically higher incidence of IBS and colitis among the celiac population than is found outside the celiac population.

Okay, thank you so much for looking.  I suppose I can throw all hope that I don't have celiac out the window now then and start focusing on going gluten free.  Much appreciated!

[trents]

You have already had both kinds of diagnostic procedures done (antibody and scoping/biopsy) and there are no more diagnostic tools left to check for celiac disease. Everything points to the fact that you are a celiac. Any more holding out would amount to denial. Start the gluten-free diet.