High CRP

[koalaemily]

Pre diagnosis my crp was 32 and my abdominal pain was every  couple mos and last a a day or two and now after going gluten free for over 4 mos my crp only went down to 23. my antibodies went down significantly too..from 99 to 17. My problem is my abdominal pain has worsened and become more frequent. i had ct scans in the past like 4 mos ago and everything came back normal. IBD panel negative. my calopectin levels in stool were mildly elevated. Can anyone shed some light on what could be going on? i am feeling worse after going gluten free than when i was consuming gluten. Im also concerned about how high my crp is still. 

 

[koalaemily]

Just now, koalaemily said:

Pre diagnosis my crp was 32 and my abdominal pain was every  couple mos and last a a day or two and now after going gluten free for over 4 mos my crp only went down to 23. my antibodies went down significantly too..from 99 to 17. My problem is my abdominal pain has worsened and become more frequent. i had ct scans in the past like 4 mos ago and everything came back normal. IBD panel negative. my calopectin levels in stool were mildly elevated. Can anyone shed some light on what could be going on? i am feeling worse after going gluten free than when i was consuming gluten. Im also concerned about how high my crp is still. 

 

for reference my pain is midline from epigastric are down to navel. The pain is mainly at night and middle of the night hours and when laying down.

[trents]

Have you been diagnosed with celiac disease? You don't really say.

[koalaemily]

Yes I am diagnosed celiac since September

[trents]

Have you been checked for H. Pylori? Peptic ulcers? GERD? Hiatal hernia? Pancreatitis? 

[koalaemily]

My lipase and liver enzymes were all good. Nothing showed up on the endoscopy and biopsy normal. The small intestine biopsy only showed mild inflammation changes( no villous atrophy yet- early celiac diagnosis due to elevated blood antibodies TTG IGG ( 99) and those minor changes seen in biopsy. H pylori negative in stool sample. I'm really at a lost. The pain is mainly at night too.

[trents]

So, you say you had a TTG IGG score of 99. Did they also do the TTG IGA antibody test for celiac disease? The TTG IGA is usually the front line test done, combining good specificity for celiac disease with good sensitivity. TTG IGG is typically a secondary test done when total IGA is low or if someone has already been practicing a low gluten diet. It isn't as specific for celiac disease. By the way, when you list test scores you should also include reference ranges since with the celiac antibody tests there are no industry standard ranges. Each lab uses there own scales.

[koalaemily]

My immunoglobulin a was on the lower end ( 65)..normal range I think is above 50 or so. So possibly low normal since the range is pretty big.  My tgg iga was 7.6 which is considered normal ( below 15) by quest. Other resources I have saw state anything above 5.7 is positive for celiac. All antibody levels have gone down significantly since going gluten free but abdominal pain is worse. My tgg iga is now 2.7 and the tgg igg is 17. My CRP is what is concerning me since I haven't ingested gluten in over 5 mos and symptoms namely my gastric pain is worse and crp remains pretty high at 23.4. Upper Normal range is below 10 but ideally below 1 in a healthy individual without underlying disease.