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celiac ttg test


Jane07

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Jane07 Enthusiast

i like someone advice for someone.

how long should it take for my ttg to be normal. it gone down alot it still not in the normal range.

how long did take?


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Scott Adams Grand Master

For most celiacs it takes 6 months or more to see a big decline in tTg levels, but some people take longer.

This study indicates that a majority of celiacs don't recover until 5 years after diagnosis and starting a gluten-free diet:

However, it's also possible that what the study really shows is the difficulty in maintaining a 100% gluten-free diet. I suspect that if you looked closely at the diets of those who did not recover within 2 years might be that their diets were not 100% gluten-free. Perhaps they ate out more often, or didn't understand all of the hidden ingredients where gluten can hide. Either way, it shows how difficult recovery from celiac disease can be for most people.

According to this study:

Quote

After an average of 11 months on a gluten-free diet, 81% of patients with celiac disease and positive tissue transglutaminase IgA (tTG-IgA) at baseline will revert to negative tTG-IgA (SOR: C, disease-oriented evidence from retrospective cohort study). The intestinal mucosa of adult patients with celiac disease will return to normal after following a gluten-free diet for 16 to 24 months in only 8% to 18%. However, in children after 2 years, 74% will have a return to normal mucosa (SOR: C, diseaseoriented evidence from longitudinal studies).

 

 

Jane07 Enthusiast

its been more then a year should i be worried im really trying it gone down alot . has anyone else had this issue not a normal score after a year?

maybe i just need to wait a bit more.

Scott Adams Grand Master

If your levels have not gone down at all in a year, it's possible that your diet is not 100% gluten-free. Do you eat outside your home, for example in restaurants? If so, this is a common source of contamination. 

This article has some detailed information on how to be 100% gluten-free, so it may be helpful (be sure to also read the comments section.):

 

Also, for some people, there are other causes of elevated tTg-IgA antibodies:

 

Jane07 Enthusiast

they have gone down but they are not at the normal area . i been really trying to be healthy i was just wondering if at  a year if they should be normail. 

it seems like it could take longer thanks

RMJ Mentor

My TTG IgA was down to normal in a year, but my DGP IgA took SIX years! 

 

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