Inflammation and Menier’s disease link?

[nataliallano]

Thanks Trents I'm strict with my gluten-free diet now. I just don't feel any better. I'm going to get tested for vitamins and minerals to see if I need some supplements. For sure I got some damage that doctors call Menier's and the only way they treat it is with medicine that does damage my body more than it helps. 

 

[trents]

How long have you been strictly gluten free? Certainly, it would be good to look into vitamin and mineral deficiencies and supplementation. The B vitamins, magnesium and D3 are all very important to neurological health. Unfortunately, it can be difficult to reverse gluten-induced neurological damage damage if it has gone on for a long time. 

[Scott Adams]

The most common nutrient deficiencies associated with celiac disease that may lead to testing for the condition include iron, vitamin D, folate (vitamin B9), vitamin B12, calcium, zinc, and magnesium.  Unfortunately many doctors, including my own doctor at the time, don't do extensive follow up testing for a broad range of nutrient deficiencies, nor recommend that those just diagnosed with celiac disease take a broad spectrum vitamin/mineral supplement, which would greatly benefit most, if not all, newly diagnosed celiacs.

 

 

 

[nataliallano]

Thanks Scott I will definitely check my vitamins and minerals to see what I am missing so then I can supplement. I was very concern about my Meniers syntoms and i tryed to find some alive. Now im just realizing that my celiac is provably the root cause of my Meniers none of the 12 doctors I saw told me anything about this. 

This web site is so helpful, thanks to people like you we can get answers. 

[knitty kitty]

On 6/29/2025 at 9:30 AM, MagsM said:

I have copied in a summary of my latest bloodwork from ChatGPT below. My GP will not refer for any further investigation and given that I do not have gastric distress symptoms it doe seem that I do not have classic Celiac but may have some malabsorption issues. I am now considering just going forward with a gluten free regimen and tracking symptoms. I will see the Consultant Otolaryngologist tomorrow and will share these results. I have already ordered the B-Complex and Benfotiamine and will start that regimen soon. Any feedback and your amazing expertise truly appreciated...

Key Immunological and Nutritional Findings

Test Result Normal Range Interpretation

Tissue Transglutaminase IgA.   <0.2 U/mL.      <7.0 =            Negative   Strongly negative — rules out celiac disease

Endomysial Antibodies (IgA).    <10                                         Negative   Supports absence of celiac disease

Total IgA                                       1.94 g/L            0.65–4.21.   Normal

IgG / IgM                                      8.47 / 2.04 g/L                      Normal.      Normal immune status

✅ These results do not indicate immunodeficiency. IgA is sufficient to make celiac testing valid, and IgG/IgM are in normal range.

⚠️ Nutritional / Absorption Concerns

TestResultNormal RangeInterpretation

Folate (B9)        3.1 ng/mL.          3.1–20.5.       Low-normal — borderline deficient

Total Protein.    63 g/L.                 64–83          Slightly low

Ferritin.              33 ng/mL.           15–150.        Normal, but low-normal; could reflect depleted stores

📌 This constellation of results suggests possible subtle malabsorption, suboptimal nutrient intake, or a functional GI issue — even in the absence of celiac disease.

🔄 Implications for Ménière’s and Autoimmunity

While there's no evidence of classic autoimmune disease or celiac, subtle immune dysregulation and non-celiac gluten sensitivity (NCGS) cannot be ruled out.
Your symptoms and lab pattern could still fit with an immune-mediated or inflammatory trigger for Ménière’s flares.
Borderline nutrient deficiencies (folate, protein) may affect inner ear function or neuronal stability, indirectly exacerbating symptoms.
Nutrient absorption issues might stem from subclinical GI inflammation, dysbiosis, or food sensitivities.

💬 Suggested Talking Points for Consultant

Could a functional immune or inflammatory mechanism be driving Ménière’s in the absence of overt autoimmunity?
Does a trial of immunomodulatory therapy (e.g., steroids, antihistamines) make sense if flares persist despite dietary changes?
Would referral to a GI specialist or dietitian be appropriate, given borderline folate, protein, and symptom profile?
Continue gluten-free diet trial for 4–6 weeks to assess symptomatic improvement, even in absence of celiac serology.
Explore possibility of non-IgE food sensitivities or mast cell activation, especially if symptoms are episodic and food-triggered.

 

 

 

@MagsM

Did your doctor do the DGP IgG and DGP IgA tests or the tTg IgG test.  It looks like he just tested total IgG.  

Were you taking any medications or over the counter stuff before the test?  Some can suppress the immune system and cause false negatives.  

Edited July 29, 2025 by knitty kitty
Typo correction