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Please Interpret Blood Results!

ptkds

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ptkds Community Regular
ptkds
Posted

Ok, so I got my dd's blood results as suggested by someone on here. So, someone please tell me what they mean!!! Here they are:

The first # is the result, and the second is the Referenc Range.

DD#1: Results Ref. Range

Endomysial IGA AB: <1:5 <1:5

Transglutaminase IGA AB: 6 <20

Gliadin IGG 35.8 <=25.0

Gliadin IGA 2.5 <=25.0

Reticulin IGA AB <1:5 <1:5

DD#2: Results Ref. Range

Endomysial IGA AB: <1:5 <1:5

Transglutaminase IGA AB: 6 <20

Gliadin IGG 45.6 <=25.0

Gliadin IGA 56.3 <=25.0

Reticulin IGA AB <1:5 <1:5

ONe dr told us that DD#2 was positive, then another said she was negative. But DD#1 has alot of Celiac disease symptoms. So, please help me ASAP! I am really confused!

Thanks,

ptkds

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Willow5 Rookie
Willow5
Posted

I know these results can be sooo confusing, here is how I would conclude. (Can't claim to be an expert and am not sure if I really got it all together - it is hard to figure out)!

Transglutaminase IGA AB shows intestinal damage. Even though it is under normal limits, it still shows up and I would take it to mean that there is some damage in process. The Gliadin IgA and IgG measure the reaction to the gluten protein. Your kids show a high in one or both areas. I saw it stated once that these tests are very much like a pregnancy test, no mater how high the results are you are still positive. You cant be a little pregnant either!

Test interpretatons will state that with the Ig's, there are % of likelyness to whether or not you are celiac, - well whatever - there is still gluten sensitivety going on!

So that is how I see it - if anyone else has clearer insite, I could use more info too!

I found with my kids that the best indication was their reaction to a gluten-free diet. Can't go back - have to keep this up!

Best wishes!

Nikki2003 Contributor
Nikki2003
Posted
Ok, so I got my dd's blood results as suggested by someone on here. So, someone please tell me what they mean!!! Here they are:

The first # is the result, and the second is the Referenc Range.

DD#1: Results Ref. Range

Endomysial IGA AB: <1:5 <1:5

Transglutaminase IGA AB: 6 <20

Gliadin IGG 35.8 <=25.0

Gliadin IGA 2.5 <=25.0

Reticulin IGA AB <1:5 <1:5

DD#2: Results Ref. Range

Endomysial IGA AB: <1:5 <1:5

Transglutaminase IGA AB: 6 <20

Gliadin IGG 45.6 <=25.0

Gliadin IGA 56.3 <=25.0

Reticulin IGA AB <1:5 <1:5

ONe dr told us that DD#2 was positive, then another said she was negative. But DD#1 has alot of Celiac disease symptoms. So, please help me ASAP! I am really confused!

Thanks,

ptkds

I think it means negative for celiac. The transglutaminase IGA is the celiac test and they look neg.

That's just my opinion though.

Celina

happygirl Collaborator
happygirl
Posted

They are both indicative of having a problem with gluten.

They are ALL used for Celiac, not just the tissue transg, although it is a highly suggestive one. Please do not pass along incorrect information. It is a Celiac PANEL, not just one blood test.

Where do you live? I would recommend finding a dr. who is knowledgable about Celiac.

I'm sure others will chime in.

Rachel--24 Collaborator
Rachel--24
Posted
I think it means negative for celiac. The transglutaminase IGA is the celiac test and they look neg.

That's just my opinion though.

Celina

I believe this is innacurrate.

As Happygirl posted....the tTG is only one part of the panel. Many Celiacs do not have a positive tTG...many do not have a positive biopsy as well. tTG is specific for damage. A negative tTG indicates that damage is likely very minimal or that damage has not yet occurred.

This is a good sign....meaning that if the girls have Celiac, you have caught this early on....before alot of damage has occurred.

I think its possible that both girls have Celiac. The testing points to dd#2 most likely having it since her anti-gliadin IgA was very high....along with the IgG.

DD#1 could have it as well but only her IgG came back positive and IgG can be elevated for reasons other than Celiac. These tests arent 100% accurate. The best test of all is dietary response. If DD#1 is having symptoms....these may very well resolve on the diet.

They are both clearly having an immune response to gluten. If you cant get a definate answer from the testing or from the doctors.....try putting both girls on the diet and you will get an answer.

Jestgar Rising Star
Jestgar
Posted

You might also want to consider having total IgA done to check for deficiencies.

Nikki2003 Contributor
Nikki2003
Posted
They are both indicative of having a problem with gluten.

They are ALL used for Celiac, not just the tissue transg, although it is a highly suggestive one. Please do not pass along incorrect information. It is a Celiac PANEL, not just one blood test.

Where do you live? I would recommend finding a dr. who is knowledgable about Celiac.

I'm sure others will chime in.

Sorry about the info. That is what I got from the results she had. All her other tests were neg. and the Ttg was the only positive one. I just thought that that was the one that was to be positive for celiac. Guess I was wrong,sorry.

Celina

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tarnalberry Community Regular
tarnalberry
Posted

Here's the thing... all the IgA's were negative, and IgG's were positive, but you don't have a total IgA test for either to tell you whether or not the standard reference ranges are valid for either girl! So those 'negative' IgA results may not *in actuality* be negatives. They need a total IgA test in order to properly read those results.

chrissy Collaborator
chrissy
Posted

i can just about guarantee you they are not IgA deficient-----their numbers would most likely be ALOT lower than theirs are. my son is IgA deficient, and he hardly even registered on testing. TTG showing, but still in the normal range, does not indicate damage. raised levels of AGA can indicate other things than celiac. if it were me, i would not assume that my children had celiac disease based on thosed test results----i would want to investigate things more.

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