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Interpreting Blood Test Results!

January Flower

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January Flower Rookie
January Flower
Posted

When i had my blood test done. The IgG was slightly raised. I know that this is an antibody level, but does it specifically relate to gluten? Or can it mean anything? Since it was raised could it be raised for any other reason? And what else would raise it?

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January Flower Rookie
January Flower
Posted
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anyone?

e&j0304 Enthusiast
e&j0304
Posted

It is my understanding that antigliadin IgG is much less specific for celiac than the antigliadin IgA. I think the only reason they test for the IgG is in case you are IgA deficient. If you aren't, then it really doesn't mean much. IgG can be raised by other various conditions (including crohn's) but if yours was only slightly elevated I woudn't be concerned about it. You can do a google search for what else can raise IgG and I'm sure you'll come up with something.

I asked a ped. GI last week if a raised IgA or IgG meant anything and he totally blew me off and stated that the only test he looks at is the tTG. I didn't really care for this dr. and his bedside manner was not good but I don't know if he's right about what he said or not.

Good luck finding answers.

confused Community Regular
confused
Posted
It is my understanding that antigliadin IgG is much less specific for celiac than the antigliadin IgA. I think the only reason they test for the IgG is in case you are IgA deficient. If you aren't, then it really doesn't mean much. IgG can be raised by other various conditions (including crohn's) but if yours was only slightly elevated I woudn't be concerned about it. You can do a google search for what else can raise IgG and I'm sure you'll come up with something.

I asked a ped. GI last week if a raised IgA or IgG meant anything and he totally blew me off and stated that the only test he looks at is the tTG. I didn't really care for this dr. and his bedside manner was not good but I don't know if he's right about what he said or not.

Good luck finding answers.

I am actually waiting to find out what they mean also, my son and husband both have high IgG levels, theirs are 2 to 3 times higher then the norm tho. Some people have stated that it can be other intolerances tho, just not celiac per se. My husbands i think is lactose intolerent tho, he just switched to soy milk and feels wonderful. My son im not sure about, i do know that lots of things do make his stomach hurt, but he is being stubborn on changing what he eats,

paula

happygirl Collaborator
happygirl
Posted

Did you have the full Celiac panel run?

Anti-gliadin antibodies (AGA) both IgA and IgG

Anti-endomysial antibodies (EMA) - IgA

Anti-tissue transglutaminase antibodies (tTG) - IgA

Total IgA level

What type of symptoms do you have? Was there reason to suspect Celiac? The AGA IgG could be indicative of a gluten intolerance that is not Celiac, but has similar symptoms.

e&j---your doc is misguided, as you thought.

From Dr. Green's website: Open Original Shared Link

"Several studies have demonstrated that reliance on either anti-tTG or endomysial antibody as a single test will underestimate the prevalence of celiac disease " (there is a reference page for studies to support that sentence, in case you are interested)

e&j0304 Enthusiast
e&j0304
Posted
e&j---your doc is misguided, as you thought.

From Dr. Green's website: Open Original Shared Link

"Several studies have demonstrated that reliance on either anti-tTG or endomysial antibody as a single test will underestimate the prevalence of celiac disease " (there is a reference page for studies to support that sentence, in case you are interested)

I am actually VERY interested in any further information you can provide. My husband was willing to have the blood test done after seeing his fathers results. However, now that this ped. GI basically laughed us off about it he no longer feels the need to get tested. My father-in-law had the whole celiac panel run and his antigliadin IgA was elevated. It was 66.7 and it should have been below 25. I am wondering why they even run the test if it isn't indicative of anything?? Of course this guy told me that he doesn't even run those tests because they, "Don't tell him anything." His total IgA serum was also elevated but I realize that that doesn't mean anything. His IgG was normal as was his tTG.

Thanks for any further insight. I had been researching this prior to that GI appointment but kind of stopped after going. This GI said he thinks my 2-year-old son has Rumination Disorder after we went to see him about his reflux. That diagnosis has been weighing heavily on my mind ever since and I forgot about the celiac stuff.

Thanks again,

Shannon

January Flower Rookie
January Flower
Posted
  • Author

I had the whole Celiac Screen done. And only my IgG was slightly raised. I had the test done becuase i kept getting D off and on. But eating gluten has helped a bit, but i think it might be a Lactose problem instead. I just ate some PIZZA last night after work, that was full of GLUTEN and i feel great! So what else could be wrong wtih me? I'm still having trouble with D.

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