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Nash (nonalcoholic Steatohepatis) & Celiac


Gerri

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Gerri Explorer

Hi I new here,

I have been diagnosed with NASH, and I have been following a gluten free diet. I asked my gastro, if there was a connection with NASH and Celiac disease. I really didn't get a answer. I have many stomach problems, Ankylosing Spondylitis gene (HLA B27+), leaky gut, acid reflux, constipation, small bowel crohns, diabetes, many allergies, small amount fluid around heart, mild COPD, asthma, lactose intolerant and the list goes on.

When I started watching the gluten I ate, my bowels movements were lot softer. My severe obstructed sleep apnea, became controlled.

I am wondering if I should go back and ask my doctor to test me for Celiac disease.

Gerri


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mommida Enthusiast

I haven't had time to research an article that states a link directly to NASH, but there is a direct link to diabetes.

Many Celiacs have test results with elevated liver enzymes. There is a link to auto-immune liver disease. (I don't know the name, but my daughter's ped. gastro. warned me about it. It could be NASH for all I know.)

You have enough reseasons to be tested for Celiac, but you would have to eat gluten. If you feel better on a gluten free diet, do you really want to start eating gluten for testing?

CaraLouise Explorer

I had elevated liver enzymes before I went gluten free and then after going gluten free they went back down. However, that was about 3 1/2 years ago and then last fall I was having blood work done and they were slightly elevated again. I was working around gluten, but still had a gluten free diet and I am no longer working around gluten. I was wondering if anyone experienced the same thing and more about liver disease (I do not drink alcohol or do any of the other causes of liver disease). Any input is appreciated! Also, how long should I wait to be retested?

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    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
    • Scott Adams
      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
    • Seaperky
      I found at Disney springs and Disney they have specialist that when told about dietary restrictions they come and talk to you ,explain cross contamination measures tsken and work with you on choices. Its the one place I dont worry once I've explained I have celiac disease.  Thier gluten free options are awesome.
    • Churley
      Have you tried Pure Encapsulations supplements? This is a brand my doctor recommends for me. I have no issues with this brand.
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