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Dapsone And Pregnancy!


fortuna

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fortuna Newbie

Hi,

I have DERMATİTİS hERPETİFORMİS and I have been taking Dapsone for 8 years. I'm a pregnant 6 weeks now. My dermatolog proposed stop to take dapson but she was not sure. She said you should don take it during first 4 months.

I have stopped it for 6 days but my everywhere covered lesions. I have itching so much. I can't sleep, go to work...I am very very sad.

I consulted another doctors. Most of them say you can take, some of them say you should not take it.

What can I do? Please say something. Maybe you took dapson while you are pregnant. Everything is good for your babies. Please help me!


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lovegrov Collaborator

Are you gluten free? If not, that's what you really need to do.

richard

fortuna Newbie
Are you gluten free? If not, that's what you really need to do.

richard

Yes, I do this diet exactly but my lesions still continue without Dapsone :(

Esra

ItchyMeredith Contributor

I am sorry to tell you that Dapasone is a class C drug.

Pregnancy Category C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans.

It is also an L4 class (bad) for breastfeeding.

As long as you are pregnant or nursing you should not take the drug. Early pregnancy is the most fragile as the organs are forming. Most doctors only recommend class A and B drugs.

Are you getting accidentally glutened? Do you have a lot of iodine in your diet? Some people have their rash worsened by foods that contain iodine like iodized salt or seafood. NSAID drugs like Advil can make it worse in some people too.

I am sorry you have to go through this. I know how intense the itching can be. I really hope you figure this out!

Good luck.

  • 1 month later...
jhow32000 Rookie

OMG, NO!!! You should not be taking this, esp during the most important trimester in your babies development. All you have to do is google Dapsone and you'll see that the research either contraindicates the Dapsone during preg/lact or says they are not sure it is safe. I know the DH is painful but you have to suck it up for your baby. My sister is experiencing the exact same issue right now and has decided against potentially harming her baby and will suffer through the flare ups. I would not go back to a doc that told you to take that stuff through the first 4 months of your pregnancy.

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    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
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