Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Enterolab

OBXMom

Recommended Posts

OBXMom Explorer
OBXMom
Posted

Can anyone tell me if it is worse to have both elevated Fecal Antigliadin & Fecal Antitissue Transglutaminase, rather than just the first? We got our Enterolab results today, and I'm comparing my daughter and myself.

Fecal Antigliadin IgA - Hers - 182, Mine - 16

Fecal Antitissue Transglutaminase IgA - Hers 103, mine -normal range (8)

I know when you are positive, you are positive, but don't her higher numbers, plus the double positive, indicate her system is having more problems right now?

Also, I am embarassed to admit I need help with the genetic info. I have read a number of posts, but I can't figure out which part of the numbers you turn into the DQ1 & 2 and so on.

Hers: HLA - DQB1, Allele 1 0201

HLA-DQB1, Allele 2, 202

HLA-DQ 2,2 (Subtype 2,2)

Mine HLA-DQB1, Allele 1, 202

HLA-DQB1, Allele 2, 0603

HLA-DQ 2,1 (Subtype 2,6)

Thank you for any help. All evening I've been trying to figure this out, and I feel like the little engine that could (I think I can, I think I can . . .)

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


holiday16 Enthusiast
holiday16
Posted

Did you happen to figure out the gene part yet? My son had the same DQ2 (0202) and it took me a while to figure out how it was different from the DQ2 (0201). Wikipedia helped alot, but wow is it confusing!!!

fedora Enthusiast
fedora
Posted

hi,

Your daughter has the celiac gene DQ2. This is also known as DQ2.5. It is HLA - DQB1, Allele 1 0201

It can cause full blown celiac. She must have got this from her dad.

The other gene is DQ2.2. It is HLA-DQB1, Allele 2, 202. I has half of the celiac gene DQ2. It is definately a gluten intolerant gene and in some instances it can cause full blown celiac. She got this gene from you.

You have the same DQ2.2 gene. so you have half the celiac gene which sometimes(rarely) manifests as full blown celiac.

DQ6 your other gene is seen in gluten intolerant patients.

The difference in the antibody levels is your daughter has antibodies against her own body tissue(the ttg antibodies). This is worse. Yours may have gotten higher over time.

You both are reacting to gluten. Did you get the malabsorption test done too?

Hope she is feeling better.

neesee Apprentice
neesee
Posted

Here's a little extra info. Open Original Shared Link

OBXMom Explorer
OBXMom
Posted
  • Author

Thank you all for your help. I hadn't figured it out yet, and finally called Enterolab today, and was promised a callback in 48 hours, which didn't thrill me. But now I really don't need them, thanks to you. But it is just so complicated, isn't it?

Fedora, we did do the malabsorption test, and we were both o.k. there. However, my daughter was also positive for anti-casein (cow's mlk) at 108 units, with <10 being normal. I didn't realize that she had antibodies against her own tissue, thank you for explaining that, although I have to admit it sounds scary. I'm wondering if she might have a leaky gut.

Thanks again, now I can go back and read all the stuff with the genes abbreviated and know which we are.

fedora Enthusiast
fedora
Posted

OBXMom

Thank is great that your malabsorption was fine. Mine was too. I was gluten and casein intolerant. I also had ttg antibodies against my own tissue. This is how the auto immune damage is done. Has their dad been checked? They had to have gotten the celiac gene from him.

I am awaiting my DD enterolab results. I am officially impatient today. It has been over 2 weeks.

nora-n Rookie
nora-n
Posted

Here is the wiki:

Open Original Shared Link

enterolab reporting which kind of DQ2 beta chain they found, is a bit new, i did not read postings of reports like taht last year.

The latest news are also that some other labs test for the alpha chains, to find the half genes, which also predispose for celiac. Enterolab does not test for them, but Kimball genetics does, but they do not test for anything but DQ2 or 8, so some peole might end up to have to order two sets of genetic tests, one from enteroplab and one from Kimball genetics...

Open Original Shared Link

Open Original Shared Link

nora

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


OBXMom Explorer
OBXMom
Posted
  • Author
OBXMom

Thank is great that your malabsorption was fine. Mine was too. I was gluten and casein intolerant. I also had ttg antibodies against my own tissue. This is how the auto immune damage is done. Has their dad been checked? They had to have gotten the celiac gene from him.

I am awaiting my DD enterolab results. I am officially impatient today. It has been over 2 weeks.

Hi Fedora,

My husband says he will just do a gluten free trial with us, but I wonder if he would be more convinced if we tested him, too. His only symptoms are bad allergies and skin rashes (not DH.)

I have to tell you, I checked Enterolab constantly to make sure the results weren't posted while we waited, and the day that I thought was 3 weeks I called. They said they were exactly at 3 weeks (starting count the day after they received the kit) and that it would come at the end of the next day. They meant it - I got them at about 5:00 pm. Maybe you will be luckier than we were, but if I were you I wouldn't expect it early. . .

OBXMom Explorer
OBXMom
Posted
  • Author

Thank you, Nora, I will pore over these. I wish I could absorb all of this more quickly. I really appreciate the help.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,807
    • Most Online (within 30 mins)
      7,748
    MoonBear
    Newest Member
    MoonBear
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • KathyR37
      New here

      By KathyR37 · Posted

      Thank you for your response. I have already learned about the info you sent but i appreciate your effort. I am the only one in my family cursed by this disease. I have to cook for them too. I make sure that my utensils are free of gluten and clean after using them for other food. I use non-porous pots and pans and  gloves when cooking for them. One huge problem I have is a gag reflex out of this world and if something doesn't taste good it is not going down. Most commercially made breads and such taste like old cardboard.Pastas are about the same. I did find one flour that I like and use it regularly, but it is so expensive! All gluten free food is way more expensive. I only eat twice a day because I cannot afford to buy all that. We live on a very low income so my food purchases are quite limited.
    • Scott Adams
      New here

      By Scott Adams · Posted

      What you've described—the severe weight loss, the cycle of medications making things worse, and the profound fear of eating before leaving the house—is a heavy burden to carry for 15 years. It is absolutely not your fault. While everyone's journey with celiac is different, the struggles with the learning curve, social isolation, and dietary grief are feelings many in the community know all too well. Your question about whether you should just eat what you want and manage the symptoms is a heartbreaking one, born from years of frustration. It's crucial to know that the diarrhea is a sign of ongoing damage to your small intestine from gluten, and simply managing the symptom with Imodium doesn't stop that internal harm or the risk of other complications. The fact that you are still getting sick within an hour of eating, even while trying to be gluten-free, is a huge red flag that something isn't right. This could be due to cross-contamination in your kitchen (e.g., using a shared toaster, colander, or condiment jars), hidden gluten in foods, or the possibility of another concurrent condition like refractory celiac disease. Don't give up!  This article has some detailed information on how to be 100% gluten-free, so it may be helpful (be sure to also read the comments section.):    
    • KathyR37
      New here

      By KathyR37 · Posted

      I am new here but celiac disease is not new to me. I was diagnosed with it at age 60. At the time I weighed a whopping 89 pounds. I was so ignorant to celiac so I buried myself in learning all about it and looking for food I could eat. I lost so much weight and stayed sick all the time. So to combat the sickness I was give all sorts of meds for loose bowels and vomiting. All that just made me sicker. Eventually I chucked it all and went back to eating like I had all my life. Now I am from the south and biscuits and gravy are a big part of our food, as are breaded foods, pasta, and sandwich bread. Through the years I would try to do the gluten free thing again and am doing it now. It has not helped any. Within and hour of eating I have to run to the bathroom. I am now 75 and am wondering if I should just forget it and eat what I like, take Immodium and live the best I can. I cannot eat before going anywhere for fear of embarrassing myself. Family and church dinners are out of the question unless I eat and run straight home. I am so frustrated I just want to sit down and cry or throw something. Does everyone go through all this?
    • Scott Adams
      Celiac attack confusion and anxiety

      By Scott Adams · Posted

      This article, and the comments below it, may be helpful:    
    • nanny marley
      Manitol and mri

      By nanny marley · Posted

      Oh yes I can understand the tiredness after going threw all that, must be exhausting especially on the mind I have high aniexty so I can understand that , I wish there more easier ways for people to get help , I had a MRI on my spine some years ago without anything it was really quick and no prep , I understand the need for  them to see better with the bowel ,but you think they would use something a little less traumatic  for ibd sufferers on the bowels by now ,I hope your feeling better today 🙏
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.