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Please Help Me Understand Gliadin Ab Igg 90 Results


dannyutah

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dannyutah Newbie

Hi folks, any help here would be so greatly appreciated. Here is my story, about 6 years ago I experienced some massive stress and shortly there after had some extremely unpleasent stomach problems mostly nausea, strange yellowish foul smelling stool, tiredness and weight loss but also on several occasions a reaction that included shortness of breath followed by extreme vomiting. This lead me to the doctor and a 2 month long stomach condition that was later written off as stress induced IBS after having every test in the book. However at one point I was told I had tested positive for Celiac, this was later dropped after my Gastro Dr took a biopsy and said test results weren't strong. I've been better since but never really the same. For a short time I was on the gluten free diet but after feeling better I stopped it since my gastro doc said don't worry about it.

Well here I am today feeling really really tired with weight loss and having some similar stomach movements as before, all after a massive stress issue. I've had a CT scan which showed nothing and all other tests seem fine except for a Epstein Bar positive that looks to be long past its infectious period. So anyway I asked my doc about that Celiac test from years before and she gave me the results which I never looked at before. Needless to say it looks like I need to look more into this.

GLIADIN AB IGA = 9

GLIADIN AB IGG =90

I am really puzzled by this IGG 90 score, thats a strong positive from what I'm reading here on the test results. From what I've read this 90 should be pretty definitive that I have an intolerance to gluten or at the least a strong allergy to it. Can anyone enlighten me with thoughts. I've read that some people only experience their gluten intolerance after stress, is this possible?

Dan


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Lisa Mentor

Dan,

Here is a link that might be of interest to you: Open Original Shared Link

For those of us with Celiac Disease, a gluten reaction can occur when ever gluten is ingested.

Often times, the disease itself can be triggered by stress, surgery, pregnancy or illness. Once it's triggered, it is with you for life. It certainly was with me. During a period of high stress my Celiac Disease was triggered, although I had no clue what was wrong at the time.

You found a great site here, with tremendous information.

dannyutah Newbie

Thanks for the response, I visited the page in your link. I'm still confused a bit. I see that the IGG score being strong isn't enough to predict Celiac, but I guess I can assume my body doesn't like gluten if I do have a strong IGG count? Can anyone tell me if a IGG score of 90 is very strong or can that be just a mild reaction?

dogle Apprentice
Hi folks, any help here would be so greatly appreciated. Here is my story, about 6 years ago I experienced some massive stress and shortly there after had some extremely unpleasent stomach problems mostly nausea, strange yellowish foul smelling stool, tiredness and weight loss but also on several occasions a reaction that included shortness of breath followed by extreme vomiting. This lead me to the doctor and a 2 month long stomach condition that was later written off as stress induced IBS after having every test in the book. However at one point I was told I had tested positive for Celiac, this was later dropped after my Gastro Dr took a biopsy and said test results weren't strong. I've been better since but never really the same. For a short time I was on the gluten free diet but after feeling better I stopped it since my gastro doc said don't worry about it.

Well here I am today feeling really really tired with weight loss and having some similar stomach movements as before, all after a massive stress issue. I've had a CT scan which showed nothing and all other tests seem fine except for a Epstein Bar positive that looks to be long past its infectious period. So anyway I asked my doc about that Celiac test from years before and she gave me the results which I never looked at before. Needless to say it looks like I need to look more into this.

GLIADIN AB IGA = 9

GLIADIN AB IGG =90

I am really puzzled by this IGG 90 score, thats a strong positive from what I'm reading here on the test results. From what I've read this 90 should be pretty definitive that I have an intolerance to gluten or at the least a strong allergy to it. Can anyone enlighten me with thoughts. I've read that some people only experience their gluten intolerance after stress, is this possible?

Dan

Dan, I don't know whether you might have celiac disease or not. There is a normal range for gliadin antibodies and if your results are higher than that, then you should get an IgA antibody and antiendomysium AB. This goes like this: if you are found to have normal IgA blood antibodies levels, and then, the antiendomysial antobody comes negative your might not have celiac disease but if it does result in a positive level you are celiac. I have read that antiendomysial antibody is the most specific test (high specificity means no other disease can show positive antiendomysial antibodies, so it is almost unique for celiac disease) however, the sensibility is quite low (sensibility is the power of the test to dectect the disease) since you might have IgA deficiency. I hope this helps you.

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    • Scott Adams
      If your tTg-IgA was 28 and positive is at 3, you are nearly 10x over the positive marker, so the most likely explanation by far would be celiac disease. I also do not understand why your doctor would not want to run the blood test, which is the normal first step in the diagnosis process.
    • xxnonamexx
      Is there a digestive enzyme that helps build a healthier gut? I see people taking them but not sure what really works
    • trents
      So the tTG-IGA at 28 is positive for celiac disease. There are some other medical conditions that can cause elevated tTG-IGA but this is unlikely. There are some people for whom the dairy protein casein can cause this but by far the most likely cause is celiac disease. Especially when your small bowel lining is "scalloped". Your Serum IGA 01 (aka, "total IGA") at 245 mg/dl is within normal range, indicating you are not IGA deficient. But I also think it would be wise to take your doctor's advice about the sucraid diet and avoiding dairy . . . at least until you experience healing and your gut has had a chance to heal, which can take around two years. After that, you can experiment with adding dairy back in and monitor symptoms. By the way, if you want the protein afforded by dairy but need to avoid casein, you can do so with whey protein powder. Whey is the other major protein in dairy.
    • jenniber
      hi, i want to say thank you to you and @trents   . after 2 phone calls to my GI, her office called me back to tell me that a blood test was “unnecessary” and that we should “follow the gold standard” and since my biopsy did not indicate celiac, to follow the no dairy and sucraid diet. i luckily have expendable income and made an appt for the labcorp blood test that day. i just got my results back and it indicates celiac disease i think 😭   im honestly happy bc now i KNOW and i can go gluten free. and i am SO MAD at this doctor for dismissing me for a simple blood test that wouldn’t have cost her anything !!!!!!!!!!! im sorry, im so emotional right now, i have been sick my whole life and never knew why, i feel so much better already   my results from labcorp:   Celiac Ab tTG TIgA w/Rflx Test Current Result and Flag Previous Result and Date Units Reference Interval t-Transglutaminase (tTG) IgA 01 28 High U/mL 0-3 Negative 0 - 3 Weak Positive 4 - 10 Positive >10 Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy. Immunoglobulin A, Qn, Serum 01 245 mg/dL 87-352
    • JoJo0611
      Thank you this really helped. 
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