Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Blood Test Results...i'm Confused!

Baddfrog

Recommended Posts

Baddfrog Rookie
Baddfrog
Posted

Hello,

My GP Doc doesn't have much experience with Celiac, so he ran a blood test for me, but when I got confusing results he wasn't sure what was up. Can anyone help me with this please?

These were my test results

Gliadin IgG Antibodies <10 U/ml

Gliadin IgG Antibodies <5 U/ml

tTg IgA Auto = 62.5 U/ml

tTg IgG Auto < 6 U/ml

I'm confused...I've heard you can have false positives with tTg-IgA but 62.5 seems a bit high for a false positive...any thoughts?

Also, if it isn't Celiac is this symptomatic of Crohn's or Liver issues or....anything.

Thank you so much for your help,

Thanks,

Scott

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


ShayFL Enthusiast
ShayFL
Posted

Hi Scott,

We need to see "references ranges" to help you. There is always a possibility of a false POS and a false NEG with ANY test. Why? Individual biochemical makeup and proficiency of the lab technician running your labs.

Depending on the range, that is a high number from the ranges I have seen.

With those results, you should request to see a GI doctor and inquire about a biopsy.

Your doctor seems receptive.....so ask if he will run a Celiac genetic test. It doesnt dx Celiac, but is a piece to the puzzle.

Baddfrog Rookie
Baddfrog
Posted
  • Author

Sorry about that.

the reference ranges are

AGA IgA < 5 U/ml

AGA IgG < 10 U/ml

tTg IgA < 4 U/ml

So my AGA numbers seem Negative...but my tTg IgA seems strongly positive.

What is the Celiac genetic test...I'm not familiar with that.

ShayFL Enthusiast
ShayFL
Posted

They take either blood or a cheek cell swab and then test for DQ2 and DQ8 genes. Those are the two genes associated with Celiac.

You really should see a specialist next (GI Doctor).

I am assuming you have symptoms and that led you to the doctor and a Celiac test to begin with.

Even if EVERYTHING came back NEG (which yours didnt) a trial of a gluten-free diet can give startling results (as it did for me). I am not Celiac, but I AM gluten intolerant. No doubt about it. My bi-monthly migraines that plagued me for years went away within 2 weeks of the diet and have never come back. My trips to the bathroom are fewer and perfectly normal. And other symptoms are improving as well.

mftnchn Explorer
mftnchn
Posted

Scott, this is a positive, so yes, biopsy is next. Dom't go gluten free until after the biopst though. You might do some research on GI's, not all are this best with celiac.

happygirl Collaborator
happygirl
Posted

The tTG is one of the best tests out there for Celiac....if that's positive, there is a very, very high likelihood that you have Celiac. You don't have to be positive on all of them to have Celiac. Having a positive tTG is more diagnostic (Celiac wise) than only a positive AGA IgA or AGA IgG.

Some good, reputable websites, besides this one are:

www.celiacdisease.net

www.celiacdiseasecenter.columbia.edu

www.celiac.org

www.celiaccentral.org

They all have info on testing, as well. Good luck.

Baddfrog Rookie
Baddfrog
Posted
  • Author

Thank you all for your input.

I thankfully got an appt with a GI, based on a cancellation, for tomorrow morning!!...and he is the only one in Akron listed on celiac.com!! I can't help but speculate on some Divine intervention there.

I want to make sure that I ask the right questions.

Any thoughts?

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


mom4life Newbie
mom4life
Posted

Hi

i am new to Celiacs and blogging! So please be patient with me. I went into doc after a month of being sick for no reason. I tested positive on one of the blood tests(waiting for call back from doc to tell me which one). I was wondering why the advice was to wait to go gluten free until after the biopsy? Won't the damage be done already? My appt with GI specialist is not until nov. 11!! I don't really want to wait that long to feel better! Any advice? I am spending my day surfing these sights for information. Thank goodness for technology!!

leadmeastray88 Contributor
leadmeastray88
Posted
Hi

i am new to Celiacs and blogging! So please be patient with me. I went into doc after a month of being sick for no reason. I tested positive on one of the blood tests(waiting for call back from doc to tell me which one). I was wondering why the advice was to wait to go gluten free until after the biopsy? Won't the damage be done already? My appt with GI specialist is not until nov. 11!! I don't really want to wait that long to feel better! Any advice? I am spending my day surfing these sights for information. Thank goodness for technology!!

Hi mom4life,

Being gluten free for even a few days can make your biopsy turn out to be a false negative. The villi in many people's intestines can heal quickly so I wouldn't take any chances. The biopsy is the 'gold standard' for a Celiac diagnosis so I would urge you to keep eating gluten until the biopsy - trust me, it'll be worth it! That way, you'll never have a doubt in your mind years later that you're doing the right thing.

Hang in there! You're on the right track.

Good luck!

-Kim

cat3883 Explorer
cat3883
Posted

Is that Akron Ohio you are from? If so I am from that area and am newly diagnosed. There is a 4 hour seminar at the Mustard Seed this Saturday from noon-4 in Fairlawn. I am curious to see who you doc is. Mine is Dr Vencat.

Baddfrog Rookie
Baddfrog
Posted
  • Author
Is that Akron Ohio you are from? If so I am from that area and am newly diagnosed. There is a 4 hour seminar at the Mustard Seed this Saturday from noon-4 in Fairlawn. I am curious to see who you doc is. Mine is Dr Vencat.

Hey Cat

Dr. Vencat is my Doc and I just met him today....I'm going in for a biopsy on Wednesday to confirm Celiac. I'm planning on going to the Mustard Seed on Saturday. How fortuitous (pretty sure I've never written that word before) is the timing on that!

I just read an article in the Beacon regarding a restaurant called the Bistro of Green that is serving gluten free dishes. I'm going to check that out once the biopsy is done.

What do you think of Dr. Vencat? Has he done a good job for you?...and how long have you been diagnosed? biopsy?

-Scott

cat3883 Explorer
cat3883
Posted

OMG My biopsy is Wednesday!! I was diagnosed about 3 weeks ago. He could tell by my bloodwork and then did the genetic test and it came back positive. He is a wonderful easy to talk to doctor. My husband and friends have gone to them for their colonoscopy. I am also having one of those done on Wed. since I am 49. I am the "overweight" celiac patient. I gained about 30 pounds over the last few years and it wont come off. I strength train and do cardio 5 days a week and my weight just wont budge. I also have depression, migraines, and fatigue. My family physician ran all kinds of bloodwork on me and that is where this celiac diagnosis began. You are in very good hands. I hope the seminar at the Mustard Seed is very informative because as you know I must start the gluten free diet on Wed!!!

There is also a place on Cleveland Ave in North Canton called the Rasin Rack that has alot of gluten free products. Good luck on Wednesday. And maybe we will meet on Saturday.

Cheryl

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. knitty kitty
      - knitty kitty replied to rei.b's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      14

      High DGP-A with normal IGA

      @rei.b, I understand how frustrating starting a new way of eating can be. I tried all sorts of gluten-free processed foods and just kept feeling worse. My health didn't improve until I started the low histamine AIP diet. It makes a big difference. Gluten fits into opioid receptors in our bodies. So, removing gluten can cause withdrawal symptoms...
    2. captaincrab55
      - captaincrab55 replied to lmemsm's topic in Gluten-Free Foods, Products, Shopping & Medications
      11

      Finding gluten free ingredients

      Imemsm, Most of us have experienced discontinued, not currently available or products that suddenly become seasonal. My biggest fear about relocating from Maryland to Florida 5 years ago, was being able to find gluten-free foods that fit my restricted diet. I soon found out that the Win Dixie and Publix supper markets actually has 99% of their gluten-free...
    3. rei.b
      - rei.b replied to rei.b's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      14

      High DGP-A with normal IGA

      Okay well the info about TTG-A actually makes a lot of sense and I wish the PA had explained that to me. But yes, I would assume I would have intestinal damage from eating a lot of gluten for 32 years while having all these symptoms. As far as avoiding gluten foods - I was definitely not doing that. Bread, pasta, quesadillas (with flour tortillas) and...
    4. knitty kitty
      - knitty kitty replied to rei.b's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      14

      High DGP-A with normal IGA

      So you're saying that you think you should have severe intestinal damage since you've had the symptoms so long? DGP IgG antibodies are produced in response to a partial gluten molecule. This is different than what tissue transglutaminase antibodies are produced in response to. TTg IgA antibodies are produced in the intestines in response to...
    5. rei.b
      - rei.b replied to rei.b's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      14

      High DGP-A with normal IGA

      I was tested for celiac at the same time, so I wasn't taking naltrexone yet. I say that, because I don't. The endoscopy showed some mild inflammation but was inconclusive as to celiac disease. They took several biopsies and that's all that was shown. I was not given a Marsh score.
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      132,132
    • Most Online (within 30 mins)
      7,748
    Exhausted-momma
    Newest Member
    Exhausted-momma
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Who's Online (See full list)

  • Upcoming Events

  • Posts

    • knitty kitty
      High DGP-A with normal IGA

      By knitty kitty · Posted

      @rei.b,  I understand how frustrating starting a new way of eating can be.  I tried all sorts of gluten-free processed foods and just kept feeling worse.  My health didn't improve until I started the low histamine AIP diet.  It makes a big difference.   Gluten fits into opioid receptors in our bodies.  So, removing gluten can cause withdrawal symptoms and reveals the underlying discomfort.  SIBO can cause digestive symptoms.  SIBO can prevent vitamins from being absorbed by the intestines.  Thiamine insufficiency causes Gastrointestinal Beriberi (bloating, abdominal pain, nausea, diarrhea or constipation).  Thiamine is the B vitamin that runs out first because it can only be stored for two weeks.  We need more thiamine when we're sick or under emotional stress.  Gastric Beriberi is under recognised by doctors.  An Erythrocyte Transketolace Activity test is more accurate than a blood test for thiamine deficiency, but the best way to see if you're low in thiamine is to take it and look for health improvement.  Don't take Thiamine Mononitrate because the body can't utilize it well.  Try Benfotiamine.  Thiamine is water soluble, nontoxic and safe even at high doses.  I thought it was crazy, too, but simple vitamins and minerals are important.  The eight B vitamins work together, so a B Complex, Benfotiamine,  magnesium and Vitamin D really helped get my body to start healing, along with the AIP diet.  Once you heal, you add foods back in, so the AIP diet is worth doing for a few months. I do hope you'll consider the AIP diet and Benfotiamine.
    • captaincrab55
      Finding gluten free ingredients

      By captaincrab55 · Posted

      Imemsm, Most of us have experienced discontinued, not currently available or products that suddenly become seasonal.   My biggest fear about relocating from Maryland to Florida 5 years ago, was being able to find gluten-free foods that fit my restricted diet.  I soon found out that the Win Dixie and Publix supper markets actually has 99% of their gluten-free foods tagged, next to the price.  The gluten-free tags opened up a  lot of foods that aren't actually marked gluten-free by the manufacture.  Now I only need to check for my other dietary restrictions.  Where my son lives in New Hartford, New York there's a Hannaford Supermarket that also has a gluten-free tag next to the price tag.  Hopefully you can locate a Supermarket within a reasonable travel distance that you can learn what foods to check out at a Supermarket close to you.  I have dermatitis herpetiformis too and I'm very sensitive to gluten and the three stores I named were very gluten-free friendly.  Good Luck 
    • rei.b
      High DGP-A with normal IGA

      By rei.b · Posted

      Okay well the info about TTG-A actually makes a lot of sense and I wish the PA had explained that to me. But yes, I would assume I would have intestinal damage from eating a lot of gluten for 32 years while having all these symptoms. As far as avoiding gluten foods - I was definitely not doing that. Bread, pasta, quesadillas (with flour tortillas) and crackers are my 4 favorite foods and I ate at least one of those things multiple times a day e.g. breakfast with eggs and toast, a cheese quesadilla for lunch, and pasta for dinner, and crackers and cheese as a before bed snack. I'm not even kidding.  I'm not really big on sugar, so I don't really do sweets. I don't have any of those conditions.  I am not sure if I have the genes or not. When the geneticist did my genetic testing for EDS this year, I didn't think to ask for him to request the celiac genes so they didn't test for them, unfortunately.  I guess another expectation I had is  that if gluten was the issue, the gluten-free diet would make me feel better, and I'm 3 months in and that hasn't been the case. I am being very careful and reading every label because I didn't want to screw this up and have to do gluten-free for longer than necessary if I end up not having celiac. I'm literally checking everything, even tea and anything else prepacked like caramel dip. Honestly its making me anxious 😅
    • knitty kitty
      High DGP-A with normal IGA

      By knitty kitty · Posted

      So you're saying that you think you should have severe intestinal damage since you've had the symptoms so long?   DGP IgG antibodies are produced in response to a partial gluten molecule.  This is different than what tissue transglutaminase antibodies are  produced in response to.   TTg IgA antibodies are produced in the intestines in response to gluten.  The tTg IgA antibodies attack our own cells because a structural component in our cell membranes resembles a part of gluten.  There's a correlation between the level of intestinal damage with the level of tTg antibodies produced.  You are not producing a high number of tTg IgA antibodies, so your level of tissue damage in your intestines is not very bad.  Be thankful.   There may be reasons why you are not producing a high quantity of tTg IgA antibodies.  Consuming ten grams or more of gluten a day for two weeks to two months before blood tests are done is required to get sufficient antibody production and damage to the intestines.  Some undiagnosed people tend to subconsciously avoid lots of gluten.  Cookies and cakes do not contain as much gluten as artisan breads and thick chewy pizza crust.  Anemia, diabetes and thiamine deficiency can affect IgA antibody production as well.   Do you carry genes for Celiac?  They frequently go along with EDS.
    • rei.b
      High DGP-A with normal IGA

      By rei.b · Posted

      I was tested for celiac at the same time, so I wasn't taking naltrexone yet. I say that, because I don't. The endoscopy showed some mild inflammation but was inconclusive as to celiac disease. They took several biopsies and that's all that was shown. I was not given a Marsh score.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.