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Details On Symptoms Linked To Celiac


Pegleg84

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Pegleg84 Collaborator

Hello,

My mother and sister were both recently diagnosed with Celiac Disease, and despite my negative blood test, I'm not ruling out the possibility that I could have it/develop it as well.

I've been doing a lot of reading on symptoms and there are a few I'd love some more information on:

1. Tooth enamel discolouration/defects: A lot of the symptoms lists include "enamel discolouration" as a possible sign of celiac. I'm only 25, don't smoke and don't drink much coffee, yet I could swear that my teeth are yellower than they should be. Also, since I was young I have had very "ridgy" teeth. My dentist has never commented on the colouration. Most descriptions of tooth enamel discolouration simply say that it gets worse with age, but what is normal for what ages? If anyone knows where to find information on this subject, that would be greatly appreciated.

2. Bruising: While reviewing the literature recently, another sign often listed is easy bruising. A while ago I would never have thought of this, but recently I've noticed that I have multiple bruises on my legs and arms despite not knowingly injuring myself. I though it could be from bumping into things at work, leaning against something for too long, or (who knows) accidentally being kicked in my sleep. However, if this is a possible warning sign, then i'd like to know more about it. Does any one have or know more about this problem?

3. Elevated Liver enzyme count: I havn't seen much about this one, but my mother (who hardly drinks a drop) has had an elevated liver enzyme count since she was about my age, and it has gone back to normal now that she is on the Diet full time (she's in her 50's now). In a recent blood test, my liver count was up as well. I've had it re-tested and havn't gotten my results back yet. Does anyone know about this?

Any information or experience you might be able to offer would be greatly appreciated.

thanks

Peggy


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Mother of Jibril Enthusiast
3. Elevated Liver enzyme count: I havn't seen much about this one, but my mother (who hardly drinks a drop) has had an elevated liver enzyme count since she was about my age, and it has gone back to normal now that she is on the Diet full time (she's in her 50's now). In a recent blood test, my liver count was up as well. I've had it re-tested and havn't gotten my results back yet. Does anyone know about this?

My alkaline phosphatase was elevated before I went on the gluten-free diet, but it's now back to normal (thank goodness!). Elevated liver enzymes indicate stress on the liver, gallbladder, and kidneys... probably from all the undigested gluten and other nutrients your intestines are having a hard time absorbing (due to the damaged villi).

gfb1 Rookie
Hello,

My mother and sister were both recently diagnosed with Celiac Disease, and despite my negative blood test, I'm not ruling out the possibility that I could have it/develop it as well.

[snip]

how were your mom/sis diagnosed?? what blood tests??

what about your dad?

Pegleg84 Collaborator
how were your mom/sis diagnosed?? what blood tests??

what about your dad?

My mom had positive blood test results right off, and recently had a clearly positive biopsy. My sister tested negative in the blood test, but they did a biopsy since she was having stomach ulcers, and also found damage to the villi.

My father passed away some years ago, so we don't know it he had it, but two of his siblings also have celiac. my mom's sister has it (as well as going through Thyroid cancer).

gfb1 Rookie
My mom had positive blood test results right off, and recently had a clearly positive biopsy. My sister tested negative in the blood test, but they did a biopsy since she was having stomach ulcers, and also found damage to the villi.

My father passed away some years ago, so we don't know it he had it, but two of his siblings also have celiac. my mom's sister has it (as well as going through Thyroid cancer).

sorry... but, you need to say which blood tests. further, if you are experiencing bruising -- for which anemia is one of the easiest/most common reasons -- it was probably included in your first round of blood tests (whether blood iron, hemoglobin, transferrin, rbs's or just packed cell volume (pcv)).

liver enzyme tests matter... ALT (alanine transaminase) and AST (aspartate transaminase) are typical for liver function tests. these exist in the hepatocytes (liver cells) themselves. ALP (alkaline phosphatase) is also measured -- but, for a different reason -- alp is found in the bile ducts and bone tissues.

mushroom Proficient
Hello,

2. Bruising: While reviewing the literature recently, another sign often listed is easy bruising. A while ago I would never have thought of this, but recently I've noticed that I have multiple bruises on my legs and arms despite not knowingly injuring myself. I though it could be from bumping into things at work, leaning against something for too long, or (who knows) accidentally being kicked in my sleep. However, if this is a possible warning sign, then i'd like to know more about it. Does any one have or know more about this problem?

Peggy

If you google "easy bruising" here on the forum you will find a lot of entries. Many of us have ended up with these purple blotches, especially on hands and legs, without recalling any injury. (I have several right now; still haven't been able to stop this from happening.) The official MD response--you have thin skin!

mimommy Contributor
Hello,

My mother and sister were both recently diagnosed with Celiac Disease, and despite my negative blood test, I'm not ruling out the possibility that I could have it/develop it as well.

I've been doing a lot of reading on symptoms and there are a few I'd love some more information on:

1. Tooth enamel discolouration/defects: A lot of the symptoms lists include "enamel discolouration" as a possible sign of celiac. I'm only 25, don't smoke and don't drink much coffee, yet I could swear that my teeth are yellower than they should be. Also, since I was young I have had very "ridgy" teeth. My dentist has never commented on the colouration. Most descriptions of tooth enamel discolouration simply say that it gets worse with age, but what is normal for what ages? If anyone knows where to find information on this subject, that would be greatly appreciated.

2. Bruising: While reviewing the literature recently, another sign often listed is easy bruising. A while ago I would never have thought of this, but recently I've noticed that I have multiple bruises on my legs and arms despite not knowingly injuring myself. I though it could be from bumping into things at work, leaning against something for too long, or (who knows) accidentally being kicked in my sleep. However, if this is a possible warning sign, then i'd like to know more about it. Does any one have or know more about this problem?

3. Elevated Liver enzyme count: I havn't seen much about this one, but my mother (who hardly drinks a drop) has had an elevated liver enzyme count since she was about my age, and it has gone back to normal now that she is on the Diet full time (she's in her 50's now). In a recent blood test, my liver count was up as well. I've had it re-tested and havn't gotten my results back yet. Does anyone know about this?

Any information or experience you might be able to offer would be greatly appreciated.

thanks

Peggy

My 8 yr. old has white marks on the enamel of her teeth that appeared at the time of her very worst symptoms before diagnosis.

Also, her liver enzymes were very elevated for many months--a mystery we never solved. The count was at one point 715, slowly going to 500, then 300 (Idon't know what 'normal' is.) Her new GI said that in all likelyhood this was due to the presence of a virus, which also caused the onset of celiac symptoms. I am looking at my notes from a conversation w/ the ped. that took place during the time when they were testing her for everything under the sun, and I had written that the ped. said she had the anitbodies for a pretty nasty virus called CMV (cytomegola (sp?) virus). That doesn't necessarily mean she had it, only that she had been exposed to it.

When I was young--say 20 years ago--I had epstein barr virus (the virus that causes mono) and my own liver enzymes were through the roof.

If I'm not mistaken, heart issues may cause elevated liver counts, and a potassium deficiency will too.


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    • Scott Adams
      This is a very common question, and the most important thing to know is that no, Guinness is not considered safe for individuals with coeliac disease. While it's fascinating to hear anecdotes from other coeliacs who can drink it without immediate issues, this is a risky exception rather than the rule. The core issue is that Guinness is brewed from barley, which contains gluten, and the standard brewing process does not remove the gluten protein to a level safe for coeliacs (below 20ppm). For someone like you who experiences dermatitis herpetiformis, the reaction is particularly significant. DH is triggered by gluten ingestion, even without immediate gastrointestinal symptoms. So, while you may not feel an instant stomach upset, drinking a gluten-containing beer like Guinness could very well provoke a flare-up of your skin condition days later. It would be a gamble with a potentially uncomfortable and long-lasting consequence. Fortunately, there are excellent, certified gluten-free stouts available now that can provide a safe and satisfying alternative without the risk.
    • MogwaiStripe
      Interestingly, this thought occurred to me last night. I did find that there are studies investigating whether vitamin D deficiency can actually trigger celiac disease.  Source: National Institutes of Health https://pmc.ncbi.nlm.nih.gov/articles/PMC7231074/ 
    • Butch68
      Before being diagnosed coeliac I used to love Guinness. Being made from barley it should be something a coeliac shouldn’t drink. But taking to another coeliac and they can drink it with no ill effects and have heard of others who can drink it too.  is this everyone’s experience?  Can I drink it?  I get dermatitis herpetiformis and don’t get instant reactions to gluten so can’t try it to see for myself. 
    • trents
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    • Scott Adams
      I will assume you did the gluten challenge properly and were eating a lot of gluten daily for 6-8 weeks before your test, but if not, that could be the issue. You can still have celiac disease with negative blood test results, although it's not as common:  Clinical and genetic profile of patients with seronegative coeliac disease: the natural history and response to gluten-free diet: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606118/  Seronegative Celiac Disease - A Challenging Case: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441776/  Enteropathies with villous atrophy but negative coeliac serology in adults: current issues: https://pubmed.ncbi.nlm.nih.gov/34764141/  Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.
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