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Difference Between New And Old Anti Gliadin Tests

MyHandful

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MyHandful Newbie
MyHandful
Posted

My rheumatologist recently blood tested me for celiac disease. The only test I tested postive on was the AGA-IGA test. He told me that it meant I most likely had celiac disease. But I did some research and found that while this test is really sensitive it's not very specific. Then I discovered I had the newer anti gliadin test done with deamidation. I found a website that said the newer tests are a little more specific for celiac disease. Does anyone know if that is true or what the difference is between the two tests? I have an endoscopy schedule for May 18th and the GI doctor thinks it will most likely come back negative, but he is going to take tissue from 5 different spots. I have been having lots of health problems that I really don't think could ALL be caused by celiac disease so I am hoping the biopsy will come back negative.

Thanks!

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JennyC Enthusiast
JennyC
Posted

Tissue transglutaminase (tTG) deaminates the gluten peptide, so a deaminated anti-gliadin test is more specific for celiac disease. Celiac may not be the only issue at hand, but celiac can cause a lot of health issues.

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