Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Pernicious Anemia And Omeprazole (prilosec)

foodiegurl

Recommended Posts

foodiegurl Collaborator
foodiegurl
Posted

I had my dr run tests last week on iron and b12 to see how they were. I have always been low in iron, but was not sure about b12.

I spoke to her today...and yes, I have low b12 ( i don't know specific numbers), and she wants me to test for pernicious anemia by taking the parietal antibody test (?), and then I will go back t her next week. She is not a GI dr...(my GI dr basically won't do anything with me until i get a biopsy..grrr...but I am doing it in 2 weeks, and then switching to a Dr at Univ of Chicago.)

Anyway....I assume she is checking the antibodies to know what is causing the low B12. Obviously, I know Celiac on its own can cause low B12, also I have been a vegetarian for about 5 years, but I do have fish about once a week.

Also, I have been taking omeprazole (prilosec) for 4 months straight...could this of effected my B12, or would this not be enough time to have an impact?

Are there a lot of people on here with Celiac and pernicious anemia?

Thanks!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


foodiegurl Collaborator
foodiegurl
Posted
  • Author

no one knows anything about this? :(

ravenwoodglass Mentor
ravenwoodglass
Posted

There are a lot of us on here that have had low B12 levels prediet because the damage from celiac can keep us from absorbing B12 from our food or supplements. Not all doctors will test for PA, as was the case with my neuro, who I saw prediagnosis, he simply told me to take sublingual B12 tablets, these bypass the damaged gut and are absorbed through the mucous membranes directly into the bloodstream and thus to the brain. If your levels are very low then they can give injections to get levels up quickly although for myself the tablets worked very well and quite fast on their own. PA is a failure of the body to produce something called intrinsic factor, many times again caused by the gut damage as that is where intrinsic factor is produced.

The best, and most likely only way, to tell if this was an effect of the med would be to check what your levels were before the med was started, if they had tested your levels prevously. A comparison with your present levels would then be of some value. You may also find that you no longer need the prilosec after you start the diet. Do check with your doctor or pharmacist to see if you should taper off the med. In some cases with acid blockers and that type of drug you can have a rebound effect if they are stopped suddenly.

I am glad to hear you are seeing the GI in a couple of weeks and getting the biopsy done. Hopefully they let you know that you must be on a full gluten diet until the biopsy is done. Please bear in mind that there are false negatives on biopsy even if on a full gluten diet. As soon as you get the procedure done you can begin the diet and your body may give you the answer before you go back for the results. I hope things improve for you soon.

foodiegurl Collaborator
foodiegurl
Posted
  • Author

I have actually been fully gluten-free for 3 months now, and the biopsy is more to check for the h.pylori, I also have, rather than the celiac. I am not going to eat gluten again!

I did not get tested before I started the prilosec, even though I requested to be :( I always ask to have my vitamins checked since I don't eat meat, but for some reason, she didn't do it last time, so I only have this test to go on.

What scares me the most is pernicious anemia...meaning "fatal" anemia :( :( This is not something I want :( I mean, gosh, I m, not even tired, or out of energy, I feel fine, so I could I have something fatal???

ravenwoodglass Mentor
ravenwoodglass
Posted
I have actually been fully gluten-free for 3 months now, and the biopsy is more to check for the h.pylori, I also have, rather than the celiac. I am not going to eat gluten again!

I did not get tested before I started the prilosec, even though I requested to be :( I always ask to have my vitamins checked since I don't eat meat, but for some reason, she didn't do it last time, so I only have this test to go on.

What scares me the most is pernicious anemia...meaning "fatal" anemia :( :( This is not something I want :( I mean, gosh, I m, not even tired, or out of energy, I feel fine, so I could I have something fatal???

PA would not be 'fatal' if the levels are brought up to normal which is easy to do once the subnormal levels are found. Try not to worry even if it is PA and not celiac related (and it is likely related to your celiac) it is treatable through the shots or sublingual tablets. It would only be fatal if it was undiagnosed for a very, very long time. If your not feeling tired or having nerve related issues like parathesias (pins and needles sensations in hands and feet) it will be easily treatable. If you are having nerve issues it is still something that can be resolved. My parasthesias disappeared within a couple weeks and the nerve damage I had repaired itself on supplements although it take take a while for me to regain stuff like reflexes in my legs.

foodiegurl Collaborator
foodiegurl
Posted
  • Author
PA would not be 'fatal' if the levels are brought up to normal which is easy to do once the subnormal levels are found. Try not to worry even if it is PA and not celiac related (and it is likely related to your celiac) it is treatable through the shots or sublingual tablets. It would only be fatal if it was undiagnosed for a very, very long time. If your not feeling tired or having nerve related issues like parathesias (pins and needles sensations in hands and feet) it will be easily treatable. If you are having nerve issues it is still something that can be resolved. My parasthesias disappeared within a couple weeks and the nerve damage I had repaired itself on supplements although it take take a while for me to regain stuff like reflexes in my legs.

I really don't think I have symptoms...lately, I have only been sleeping 7 hours a day, since i stay up late, wake up early, keep up with my 4-year old all day, and keep her social calendar full. I rarely ever nap, and by the time I do get to bed at midnight or later, I lay in bed reading for 30 min or so. So, I definitely feel like I have energy. If i had PA would I be more tired?

Lisa Mentor
Lisa
Posted

Open Original Shared Link

If your vitamin B12 level becomes low, you may develop fatigue from anemia. B12 is needed for healthy nerves, so you also may develop numbness or skin pain, tingling or weakness.

If you have been on acid blockers for more than a few years, or if you have symptoms that suggest possible vitamin B12 deficiency, then your doctor can test your vitamin B12 supply by checking a blood sample.

If you are being treated for B12 deficiency and you are taking an acid blocker, it is best to get your vitamin supplement in the form of a monthly injection, instead of a pill.

Anti-acid medicines in both the H2 blocker proton pump inhibitor groups can occasionally cause headache, diarrhea, abdominal pain or nausea. H2 blockers may cause drowsiness, dizziness or memory complaints, particularly in older adults. These problems go away if the medicine is discontinued.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,961
    • Most Online (within 30 mins)
      7,748
    Noa
    Newest Member
    Noa
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Scott Adams
      Does anyone here also have Afib

      By Scott Adams · Posted

      If black seed oil is working for his Afib, stick to it, but if not, I can say that ablation therapy is no big deal--my mother was out of the procedure in about 1 hour and went home that evening, and had zero negative effects from the treatment. PS - I would recommend that your husband get an Apple watch to monitor his Afib--there is an app and it will take readings 24/7 and give reports on how much of the time he's in it. Actual data like this should be what should guide his treatment.
    • Jacki Espo
      Covid caused reoccurrence of DH without eating gluten

      By Jacki Espo · Posted

      This happened to me as well. What’s weirder is that within a couple hours of taking paxlovid it subsided. I thought maybe I got glutened but after reading your post not so sure. 
    • Mari
      New Celiac Mama in My 30s

      By Mari · Posted

      Hi Tiffany. Thank you for writing your dituation and  circumstancesin such detail and so well writte, too. I particularly noticed what you wrote about brain for and feeling like your brain is swelling and I know from my own experiences that's how it feel and your brain really does swell and you get migraines.    Way back when I was in my 20s I read a book by 2 MD allergist and they described their patient who came in complaining that her brain, inside her cranium, was swelling  and it happened when she smelled a certain chemical she used in her home. She kept coming back and insisting her brain actually swelled in her head. The Drs couldn't explain this problem so they, with her permission, performed an operation where they made a small opening through her cranium, exposed her to the chemical then watched as she brain did swell into the opening. The DRs were amazed but then were able to advise her to avoid chemicals that made her brain swell. I remember that because I occasionally had brain fog then but it was not a serious problem. I also realized that I was becoming more sensitive to chemicals I used in my work in medical laboratories. By my mid forties the brain fog and chemicals forced me to leave my  profession and move to a rural area with little pollution. I did not have migraines. I was told a little later that I had a more porous blood brain barrier than other people. Chemicals in the air would go up into my sinused and leak through the blood brain barrier into my brain. We have 2 arteries  in our neck that carry blood with the nutrients and oxygen into the brain. To remove the fluids and used blood from the brain there are only capillaries and no large veins to carry it away so all those fluids ooze out much more slowly than they came in and since the small capillaries can't take care of extra fluid it results in swelling in the face, especially around the eyes. My blood flow into my brain is different from most other people as I have an arterial ischema, adefectiveartery on one side.   I have to go forward about 20 or more years when I learned that I had glaucoma, an eye problem that causes blindness and more years until I learned I had celiac disease.  The eye Dr described my glaucoma as a very slow loss of vision that I wouldn't  notice until had noticeable loss of sight.  I could have my eye pressure checked regularly or it would be best to have the cataracts removed from both eyes. I kept putting off the surgery then just overnight lost most of the vision in my left eye. I thought at the I had been exposed to some chemical and found out a little later the person who livedbehind me was using some chemicals to build kayaks in a shed behind my house. I did not realize the signifance  of this until I started having appointments with a Dr. in a new building. New buildings give me brain fog, loss of balance and other problems I know about this time I experienced visual disturbances very similar to those experienced by people with migraines. I looked further online and read that people with glaucoma can suffer rapid loss of sight if they have silent migraines (no headache). The remedy for migraines is to identify and avoid the triggers. I already know most of my triggers - aromatic chemicals, some cleaning materials, gasoline and exhaust and mold toxins. I am very careful about using cleaning agents using mostly borax and baking powder. Anything that has any fragrance or smell I avoid. There is one brand of dishwashing detergent that I can use and several brands of  scouring powder. I hope you find some of this helpful and useful. I have not seen any evidence that Celiac Disease is involved with migraines or glaucoma. Please come back if you have questions or if what I wrote doesn't make senseto you. We sometimes haveto learn by experience and finding out why we have some problems. Take care.       The report did not mention migraines. 
    • Mari
      My only proof

      By Mari · Posted

      Hi Jmartes71 That is so much like my story! You probably know where Laytonville is and that's where I was living just before my 60th birthday when the new Dr. suggested I could have Celiacs. I didn't go on a gluten challange diet before having the Celiac panel blood test drawn. The results came back as equivical as one antibody level was very high but another, tissue transaminasewas normal. Itdid show I was  allergic to cows milk and I think hot peppers. I immediately went gluten free but did not go in for an endoscopy. I found an online lab online that would do the test to show if I had a main celiac gene (enterolab.com). The report came back that I had inherited a main celiac gene, DQ8, from one parent and a D!6 from the other parent. That combination is knows to sym[tons of celiac worse than just inheriting one main celiac gene. With my version of celiac disease I was mostly constipated but after going gluten-free I would have diarrhea the few times I was glutened either by cross contamination or eating some food containing gluten. I have stayed gluten-free for almost 20 years now and knew within a few days that it was right for me although my recovery has been slow.   When I go to see a  medical provide and tell them I have celiacs they don't believe me. The same when I tell them that I carry a main celiac gene, the DQ8. It is only when I tell them that I get diarrhea after eating gluten that they realize that I might have celiac disease. Then they will order th Vitamin B12 and D3 that I need to monitor as my B12 levels can go down very fast if I'm not taking enough of it. Medical providers haven't been much help in my recovery. They are not well trained in this problem. I really hope this helps ypu. Take care.      
    • knitty kitty
      Does anyone here also have Afib

      By knitty kitty · Posted

      Fascinating.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.