Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Confused About Enterolab Test And Need For "gluten Challenge"


terin514

Recommended Posts

terin514 Newbie

Hi Everyone -

First of all, SO happy to have found this site. I am proceeding with Enterolab testing after years of "IBS" diagnoses and living with all of the symptoms of Celiac... and growing up in a family of people with "weak stomachs".

I have been gluten-free for about 2 - 3 weeks now and feel SO much better that I know I'll be gluten-free even if the Enterolab results do not come back positive (although I suspect they will). I guess, like many others, I'd just like the validation of the results.

But, on to my question:

The Enterolab instructions say to NOT change your way of eating (i.e. do not do a gluten challenge) before you take the test... However, I see many posts on this site recommending a gluten challenge before a test. Can someone clear this up for me? Is there something different about the Enterolab tests?

I am excited to do the test, but wondering if I should order up a couple pizzas this week (although I hate to even think of doing that - the thought of the bloating, C/D, pain, irritability and fatigue make me want to just go forth without the challenge).

Your help is VERY much appreciated!

:D


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



ang1e0251 Contributor

For an endoscopy or blood panel you need to eat gluten because one tests for antibodies and you need to eat the gluten for there to be antibodies. The other is a look at your small intestine where biopsies are taken. Again for the damage to be present you need to be producing antibodies and you must be eating gluten for that to happen.

I believe Enterolab is the gene testing which doesn't change no matter what you eat. Someone correct me if there is more to it than that.

terin514 Newbie

Thanks for the reply and the info. I thought that Enterolab did test for the antibodies... I'm doing the full panel PLUS the gene test.

Can someone let me know if there is a difference between the antibody tests, and why Enterolab would recommend NOT changing your diet or doing a gluten challenge prior to the full test?

Thanks again!

luciddream928 Explorer
Thanks for the reply and the info. I thought that Enterolab did test for the antibodies... I'm doing the full panel PLUS the gene test.

Can someone let me know if there is a difference between the antibody tests, and why Enterolab would recommend NOT changing your diet or doing a gluten challenge prior to the full test?

Thanks again!

Hi Terin! Welcome to the forum, glad you found us : ) This is a wonderful community and really supportive...

I went through Enterolab about a year ago and found them to be super helpful every time I called with questions. I did the stool panel and the genetic cheek swab. You can just call their main number and ask them what they recommend. I don't think you need to do a gluten challenge before the test, but it's been a while since I've taken it. From what I've read and heard, it doesn't matter whether you eat gluten or not because the things that they test for stay in the body for a long time. Something about the stool test being sensitive to gluten intolerance. It says it on their website in the FAQ section.

I'd call though, maybe their protocol has changed. Their number is 972.686.6869. Good luck with your test!

terin514 Newbie

Thanks again! I will call to make sure - I really appreciate everyone's help!

:D

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      132,210
    • Most Online (within 30 mins)
      7,748

    BJ OConnor
    Newest Member
    BJ OConnor
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • trents
      NCGS does not cause damage to the small bowel villi so, if indeed you were not skimping on gluten when you had the antibody blood testing done, it is likely you have celiac disease.
    • Scott Adams
      I will assume you did the gluten challenge properly and were eating a lot of gluten daily for 6-8 weeks before your test, but if not, that could be the issue. You can still have celiac disease with negative blood test results, although it's not as common:  Clinical and genetic profile of patients with seronegative coeliac disease: the natural history and response to gluten-free diet: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606118/  Seronegative Celiac Disease - A Challenging Case: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441776/  Enteropathies with villous atrophy but negative coeliac serology in adults: current issues: https://pubmed.ncbi.nlm.nih.gov/34764141/  Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.
    • Xravith
      I'm very confused... My blood test came out negative, I checked all antibodies. I suppose my Total IgA levels are normal (132 mg/dl), so the test should be reliable. Still, I'm not relieved as I can't tolerate even a single biscuit. I need to talk to my doctor about whether a duodenal biopsy is necessary. But it is really possible to have intestinal damage despite having a seronegative results? I have really strong symptoms, and I don't want to keep skipping university lectures or being bedridden at home.
    • Scott Adams
      They may want to also eliminate other possible causes for your symptoms/issues and are doing additional tests.  Here is info about blood tests for celiac disease--if positive an endoscopy where biopsies of your intestinal villi are taken to confirm is the typical follow up.    
    • Scott Adams
      In the Europe the new protocol for making a celiac disease diagnosis in children is if their tTg-IgA (tissue transglutaminase IgA) levels are 10 times or above the positive level for celiac disease--and you are above that level. According to the latest research, if the blood test results are at certain high levels that range between 5-10 times the reference range for a positive celiac disease diagnosis, it may not be necessary to confirm the results using an endoscopy/biopsy: Blood Test Alone Can Diagnose Celiac Disease in Most Children and Adults TGA-IgA at or Above Five Times Normal Limit in Kids Indicates Celiac Disease in Nearly All Cases No More Biopsies to Diagnose Celiac Disease in Children! May I ask why you've had so many past tTg-IgA tests done, and many of them seem to have been done 3 times during short time intervals?    
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.