Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Interesting New Study


srthomas21

Recommended Posts

srthomas21 Explorer

a look at the new study published in the May issue of the British Journal of Nutrition: (3)

* 30 patient with diagnosed celiac disease were placed on a gluten-free diet for a one month period.

* Pre and post study analyses indicated that the number of friendly bacteria such as Bifidobacterium and Lactobacillus diminished after the removal of the glutenous foods.

* There was also an unwelcome increase in the number of pathogenic bacteria including Enterobacteriaceae and E. coli.

* In addition to the undesirable shift in the good-to-bad bacteria population, there was evidence of decreased gut-related immune system activity.


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Glamour Explorer

Why does good flora diminish after REMOVING glutinous food...you think it would get better without all the yeast food

Swimmr Contributor

Hmm that is kinda hard to digest *pun intended* :)

Um, yeah I would like to know why the good bacteria diminishes. Perhaps when we go gluten free, the good bacteria goes away because we aren't ingesting typically "good" things in the general sense. Even though our intestines cant absorb it...ummm so it leaves...and...yeah, I'm lost :blink:

That is not easy to rationalize.

Jestgar Rising Star

You'd need a more detailed description of the gluten-free diet. If it's a bunch of high carbohydrate replacement stuff, I could see that not being so good. If they replaced gluten food with whole food, maybe the result would be different.

srthomas21 Explorer

Here is the link to the full study

I think you have to pay $45 to get it though

Open Original Shared Link

Jestgar Rising Star
Here is the link to the full study

I think you have to pay $45 to get it though

Open Original Shared Link

The link you sent me stated that the experiment was done on 10 healthy adults.

They replaced gluten containing foods with equivalent ones certified as gluten-free.

the gluten-free diet had half the polysaccharides. Also other differences, but none significant.

In the discussion they state that the decrease of 3 types of beneficial bacteria could be directly related to the decrease in polysaccharides, which serve as a direct food source for bacteria in the distal colon.

It's also a one month study. What they measured could be a temporary effect from the change in diet. You'd need a longer study to find out if the change in gut flora composition is permanent. You'd also need to look at people with Celiac to find out if the same thing happens.

TownieHeather Newbie
The link you sent me stated that the experiment was done on 10 healthy adults.

They replaced gluten containing foods with equivalent ones certified as gluten-free.

the gluten-free diet had half the polysaccharides. Also other differences, but none significant.

In the discussion they state that the decrease of 3 types of beneficial bacteria could be directly related to the decrease in polysaccharides, which serve as a direct food source for bacteria in the distal colon.

It's also a one month study. What they measured could be a temporary effect from the change in diet. You'd need a longer study to find out if the change in gut flora composition is permanent. You'd also need to look at people with Celiac to find out if the same thing happens.

Somebody else posted this study too! I don't understand why it's getting so much press when it's looks so inconclusive to me - all that things that you pointed out Jestgar along with the fact that it was only 10 people!


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



srthomas21 Explorer

I think I linked to the wrong article but now I can't find the correct one.

The study I mentioned was done on 30 Celiac patients that were newly diagnosed. I wish I could find the correct link.

chiroptera Apprentice

I find this very interesting because I had NO problems with any food at all until I almost died from a severe c. difficile infection in 2003. My gut was ripped out but thank goodness I didn't have a complex toxic megacolon that burst. SO, for me anyways, the c. difficile (I believe) caused my problems with gluten and casein.

I am SO much better now off of those foods.

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      132,201
    • Most Online (within 30 mins)
      7,748

    Judy Wysocki
    Newest Member
    Judy Wysocki
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Xravith
      I'm very confused... My blood test came out negative, I checked all antibodies. I suppose my Total IgA levels are normal (132 mg/dl), so the test should be reliable. Still, I'm not relieved as I can't tolerate even a single biscuit. I need to talk to my doctor about whether a duodenal biopsy is necessary. But it is really possible to have intestinal damage despite having a seronegative results? I have really strong symptoms, and I don't want to keep skipping university lectures or being bedridden at home.
    • Scott Adams
      They may want to also eliminate other possible causes for your symptoms/issues and are doing additional tests.  Here is info about blood tests for celiac disease--if positive an endoscopy where biopsies of your intestinal villi are taken to confirm is the typical follow up.    
    • Scott Adams
      In the Europe the new protocol for making a celiac disease diagnosis in children is if their tTg-IgA (tissue transglutaminase IgA) levels are 10 times or above the positive level for celiac disease--and you are above that level. According to the latest research, if the blood test results are at certain high levels that range between 5-10 times the reference range for a positive celiac disease diagnosis, it may not be necessary to confirm the results using an endoscopy/biopsy: Blood Test Alone Can Diagnose Celiac Disease in Most Children and Adults TGA-IgA at or Above Five Times Normal Limit in Kids Indicates Celiac Disease in Nearly All Cases No More Biopsies to Diagnose Celiac Disease in Children! May I ask why you've had so many past tTg-IgA tests done, and many of them seem to have been done 3 times during short time intervals?    
    • trents
      @JettaGirl, "Coeliac" is the British spelling of "celiac". Same disease. 
    • JettaGirl
      This may sound ridiculous but is this supposed to say Celiacs? I looked up Coeliacs because you never know, there’s a lot of diseases related to a disease that they come up with similar names for. It’s probably meant to say Celiacs but I just wanted to confirm.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.