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Dgp/iga Results Positive

patz

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patz Newbie
patz
Posted

Hi all, I just recvd panel back. All neg except the new GDP IGA came back 38. GDP IGG was neg. Doc wants me to see GI. With only one positive test but supposedly quite accurate can I assume celiac disease? I have bloating, gas, nausea and sometimes just don't feel well.

Mainly need to know if worth getting scoped on only one positive test. Help!!

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Wolicki Enthusiast
Wolicki
Posted

This is actually the first I have heard of this test. After reading this study:

Open Original Shared Link

I think that a biopsy is wise. It appears to be a very reliable indicator. Good luck!

  • 1 year later...
gfcolorado Newbie
gfcolorado
Posted

Hi all, I just recvd panel back. All neg except the new GDP IGA came back 38. GDP IGG was neg. Doc wants me to see GI. With only one positive test but supposedly quite accurate can I assume celiac disease? I have bloating, gas, nausea and sometimes just don't feel well.

Mainly need to know if worth getting scoped on only one positive test. Help!!

I just came across your post and realize it's been awhile so I'm not sure if you'll get this. I just had a positive only GDP biopsy and was wondering what your biopsy came back. Thanks!

Emsstacey Rookie
Emsstacey
Posted

gfcolorado, are you saying that only your deamidated gliadin was positive and your biopsy was positive, too?

I ask because my only antibody that came back positive was the deamidated gliadin at a 31. I did not get the scope because I had one done about 10 years ago looking for the same thing. I never did get the results, though, just told it was ok. I'm actually going to go pick them up this week to see for myself what they say.

Just curious! Thanks!

melissa222 Newbie
melissa222
Posted

I just got my results back I had deamidated gliadin antibodies at 36, along with a DQ8 gene (I got the genetic test at the same time). Other tests were negative. I have major celiac symptoms. I'm having the scope done next week. My GI Dr, who was recommended to me by a local celiac support group, said this test was a very strong indication that I do have celiac. From what I've read this test is very specific to celiac, and a valuable new test in detecting celiac in patients, like me, who have tested negative with the other tests.

Emsstacey Rookie
Emsstacey
Posted

Wow. It sounds like a lot more people with only the positive DGP. I guess that I need to go retest and find a GI. I would be very grateful if you update after your scope!

Skylark Collaborator
Skylark
Posted

DGP is considerably more sensitive than the other tests in the celiac panel.

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melissa222 Newbie
melissa222
Posted

My biopsy came back normal. Dr says it is not celiac but to try gluten free diet. I'm bummed because I thought I had hope to feel better.

ravenwoodglass Mentor
ravenwoodglass
Posted

My biopsy came back normal. Dr says it is not celiac but to try gluten free diet. I'm bummed because I thought I had hope to feel better.

Don't be bummed get on the diet. If your DGP was positive you do need to avoid all gluten. False negative biopsies are very common. Get on the diet strictly and you should be feeling better soon.

Skylark Collaborator
Skylark
Posted

My biopsy came back normal. Dr says it is not celiac but to try gluten free diet. I'm bummed because I thought I had hope to feel better.

You do have hope to feel better. My mom came back negative on antibodies and biopsy. She feels a heck of a lot better off gluten. With the DGP there is certainly something going on and you might be pleasantly surprised.

pain*in*my*gut Apprentice
pain*in*my*gut
Posted

My biopsy came back normal. Dr says it is not celiac but to try gluten free diet. I'm bummed because I thought I had hope to feel better.

My biopsy was normal, too. My GI doc dismissed me without any follow up to discuss my obvious Celiac symptoms. According to him (and a lot of docs), if the biopsy was negative, I don't have a problem. What an idiot. :angry:

When my rheumatologist took one look at my DGP levels, he said it was most certainly Celiac and to avoid gluten like the plague. :o DGP is very specific for Celiac, so in his opinion, it trumps the biopsy because of the false negative probability if the damage is patchy in the intestines.

I am now one month gluten free, and my stomach issues are 80% better than before! I think you will be pleasanly suprised by how good you will feel off of gluten! B)

gfcolorado Newbie
gfcolorado
Posted

gfcolorado, are you saying that only your deamidated gliadin was positive and your biopsy was positive, too?

I ask because my only antibody that came back positive was the deamidated gliadin at a 31. I did not get the scope because I had one done about 10 years ago looking for the same thing. I never did get the results, though, just told it was ok. I'm actually going to go pick them up this week to see for myself what they say.

Just curious! Thanks!

When I was originally tested 3 years ago, all my tests (TTG, EMA, DGP) were positive and so was my biopsy. This time, only my DGP was positive. My TTG and EMA were negative. I think I'm going to get another endoscopy just to see what's going on. If I do, I'll let you know.

gfcolorado Newbie
gfcolorado
Posted

My biopsy was normal, too. My GI doc dismissed me without any follow up to discuss my obvious Celiac symptoms. According to him (and a lot of docs), if the biopsy was negative, I don't have a problem. What an idiot. :angry:

When my rheumatologist took one look at my DGP levels, he said it was most certainly Celiac and to avoid gluten like the plague. :o DGP is very specific for Celiac, so in his opinion, it trumps the biopsy because of the false negative probability if the damage is patchy in the intestines.

I am now one month gluten free, and my stomach issues are 80% better than before! I think you will be pleasanly suprised by how good you will feel off of gluten! B)

I think there is so much they still don't know about Celiac and Gluten Sensitivity and the DGP test. When I went to a Celiac conference about 3 years ago, they hardly talked about Gluten sensitivity. When I went last year, the top Celiac researchers all talked about it. Most doctors say that you don't have Celiac until your biopsy is positive and no one really knows at what point you become positive. I had really bad stomach aches my whole life but wasn't diagnosed with Celiac until I was 43. My biopsy was positive and my stomach aches are gone but would I have tested positive when I was a kid or 10 years prior? I don't know but going off of gluten would have made my stomach aches go away and might have prevented villous atrophy and other auto immune diseases.

Thanks everyone for sharing your info!

  • 2 weeks later...
melissa222 Newbie
melissa222
Posted

Yall were right! After about 11 days gluten free my energy levels picked up and I have felt incredible...more energy, anxiety is gone, more focus...I have not felt this good in years. Now I'm going to patiently wait for my physical problems to improve! It's almost miraculous. To think had I not figured this out on my own, I would've lived out the rest of my life completely miserable. Doctors are grossly mis/uneducated about this!! All the time n money spent on Dr visits and tests, when the whole time it was food. :/ I consider myself lucky. So many suffer so much longer and never know how poisonous gluten can be. It should come with a warning label!

Skylark Collaborator
Skylark
Posted

That's wonderful news! I'm so glad to hear you're feeling better. Thanks a lot for coming back to update us and share your good news!

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    • Mari
      My only proof

      By Mari · Posted

      Years  ago a friend and I drove north into Canada hoping to find a ski resort open in late spring,We were in my VW and found a small ski area near a small town and started up this gravelled road up a mountain. We  got about halfway up and got stuck in the mud. We tried everything we could think of but an hour later we were still stuck. Finally a pickup came down the road, laughed at our situation, then pulled the VW free of the mud. We followed him back to the ski area where where he started up the rope ski lift and we had an enjoyable hour of skiing and gave us a shot of aquavit  before we left.It was a great rescue.  In some ways this reminds me of your situation. You are waiting for a rescue and you have chosen medical practitioners to do it now or as soon as possible. As you have found out the med. experts have not learned how to help you. You face years of continuing to feel horrible, frustrated searching for your rescuer to save you. You can break away from from this pattern of thinking and you have begun breaking  away by using some herbs and supplements from doTerra. Now you can start trying some of the suggestions thatother Celiacs have written to your original posts.  You live with other people who eat gluten foods. Cross contamination is very possible. Are you sure that their food is completely separate from their food. It  is not only the gluten grains you need to avoid (wheat, barley, rye) but possibly oats, cows milk also. Whenever you fall back into that angry and frustrated way of thinking get up and walk around for a whild. You will learn ways to break that way of thinking about your problems.  Best wishes for your future. May you enjpy a better life.  
    • marion wheaton
      Are Lindt chocolate balls gluten free?

      By marion wheaton · Posted

      Thanks for responding. I researched further and Lindt Lindor chocolate balls do contain barely malt powder which contains gluten. I was surprised at all of the conflicting information I found when I checked online.
    • trents
      Are Lindt chocolate balls gluten free?

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      @BlessedinBoston, it is possible that in Canada the product in question is formulated differently than in the USA or at least processed in in a facility that precludes cross contamination. I assume from your user name that you are in the USA. And it is also possible that the product meets the FDA requirement of not more than 20ppm of gluten but you are a super sensitive celiac for whom that standard is insufficient. 
    • BlessedinBoston
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      No,Lindt is not gluten free no matter what they say on their website. I found out the hard way when I was newly diagnosed in 2000. At that time the Lindt truffles were just becoming popular and were only sold in small specialty shops at the mall. You couldn't buy them in any stores like today and I was obsessed with them 😁. Took me a while to get around to checking them and was heartbroken when I saw they were absolutely not gluten free 😔. Felt the same when I realized Twizzlers weren't either. Took me a while to get my diet on order after being diagnosed. I was diagnosed with small bowel non Hodgkins lymphoma at the same time. So it was a very stressful time to say the least. Hope this helps 😁.
    • knitty kitty
      My only proof

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