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Looking For Reviews On Signet Diagnostic Corporation's Mrt Test.

Dada2hapas

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Dada2hapas Rookie
Dada2hapas
Posted

Just looking for input with LEAP. How does their immune response blood test work? Effective? Thanks. -D

Signet Diagnostic Corporation

3555 Fiscal Court Suites 8 & 9

Riviera Beach, FL 33404

Ph. 888-669-5327

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Skylark Collaborator
Skylark
Posted

Well, LEAP made the "dubious" list at Quackwatch.

Open Original Shared Link

Another abstract with a similar conclusion. The author notes that information on mediator release testing is only found on consumer sites.

Open Original Shared Link

There are a lot of scams right now with diagnostic tests, to the point that FDA is looking hard at companies like this. The other big scam allergy test is IgG4.

Dada2hapas Rookie
Dada2hapas
Posted
  • Author

Well, LEAP made the "dubious" list at Quackwatch.

Open Original Shared Link

Another abstract with a similar conclusion. The author notes that information on mediator release testing is only found on consumer sites.

Open Original Shared Link

There are a lot of scams right now with diagnostic tests, to the point that FDA is looking hard at companies like this. The other big scam allergy test is IgG4.

:) Thanks, I was aware of the paper on PubMed. Their philosophy seems to be different than mainstream medicine, but I wonder if part of the poor review is because their MRT test is proprietary. I don't know how their lab test is performed. Maybe useful to hear from folks who may have used it to their benefit, or even otherwise. LEAP claims to have helped thousands of patients successfully. Dr. Scot Lewey (who wrote pretty informative articles on celiac disease and celiac disease testing available here on celiac.com) seems to recommend it for his patients. However, there doesn't seem to be much consumer input available. Interesting.

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http://www.celiac.co...ewey/Page1.html

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Skylark Collaborator
Skylark
Posted

I'm so suspicious of testing services that refuse to establish (or at least provide) sensitivity and specificity measures for their tests.

You do realize allergists say the gold standard for food allergies is elimination, right? None of these tests "diagnose" food allergies or sensitivities. They can only guide what foods might be problematic if you're not willing to do lamb/rice/pears.

I personally think MRT, IgG4, Enterolab, and other consumer "diagnostic" services are creative ways to separate consumers from their $$ because Western medicine has people confused and overly attached to diagnostic test results.

Dada2hapas Rookie
Dada2hapas
Posted
  • Author

I'm so suspicious of testing services that refuse to establish (or at least provide) sensitivity and specificity measures for their tests.

You do realize allergists say the gold standard for food allergies is elimination, right? None of these tests "diagnose" food allergies or sensitivities. They can only guide what foods might be problematic if you're not willing to do lamb/rice/pears.

I personally think MRT, IgG4, Enterolab, and other consumer "diagnostic" services are creative ways to separate consumers from their $ because Western medicine has people confused and overly attached to diagnostic test results.

Lol. I don't disagree with you regarding LEAP. I just looked up their patents, interesting. Not "state of the art" as they advertise. I'm just surprised there has been so little commentary about it, controversial as it is.

  • 3 months later...
JaisonS Newbie
JaisonS
Posted

Lol. I don't disagree with you regarding LEAP. I just looked up their patents, interesting. Not "state of the art" as they advertise. I'm just surprised there has been so little commentary about it, controversial as it is.

A word of caution ; I spent hours researching The owner of the website QUACKWATCH ; Do it on Google and you will find that he is a physician whom license is revoked and tied big-time to large pharmaceutical industry with a lot of suspicion about his income and whom supporting his website since he is out of business . His business is to discredit everything that gives answer to disease other than mainstream medicine that is hooked on giving lifetime drugs. Do not take my word for it checj it out yourselves. Signet MRT follows strict testing procedures and is used by Functional Medicine , Anti-Aging medicine all over the US and abroad ( ask someone who used it ) ; also used by metabolic typing . Do your homework . research and get well informed. A lot of websites are out-there to discredit money making drug companies and their allied health care providers. I do not do forums a lot but happened to see this part . Good luck .

  • 1 month later...
MiDoc Newbie
MiDoc
Posted

Well, LEAP made the "dubious" list at Quackwatch.

Another abstract with a similar conclusion. The author notes that information on mediator release testing is only found on consumer sites.

There are a lot of scams right now with diagnostic tests, to the point that FDA is looking hard at companies like this. The other big scam allergy test is IgG4.

Yeah, that quackwatch guy, Open Original Shared Link, is no more reliable as a source of information than Glenn Beck. In one case that Open Original Shared Link and the "Open Original Shared Link" tried to file against an alternative health company, the judge found Open Original Shared Link to be "biased and unworthy of credibility".

I haven't tried the LEAP test with any patients, but have used a combined IgE/IgG4 with a lot of people and it usually helps find things that people feel better when they don't eat, so the idea that it is necessarily "a scam" isn't supported by my experience. However, it is not diagnostic for celiac disease.

In my experience, no test is 100%. An elimination diet with careful re-challenging after 2w off all common allergens is the best bet for finding food sensitivities. The blood tests give a short-cut so people can do a smaller challenge.

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Skylark Collaborator
Skylark
Posted

Interesting. Your experience directly contradicts this peer-reviewed evaluation of IgG4.

Open Original Shared Link

"In conclusion, food-specific IgG4 does not indicate (imminent) food allergy or intolerance, but rather a physiological response of the immune system after exposition to food components. Therefore, testing of IgG4 to foods is considered as irrelevant for the laboratory work-up of food allergy or intolerance and should not be performed in case of food-related complaints."

As for Quackwatch, have you actually read the website? It's common sense stuff, largely based on peer-reviewed research and not all written by Barrett. Try this classic one on homeopathy. It's a wonderful read. Open Original Shared Link

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